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Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environme… Read more
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Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Stem Cell Manufacturing
discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product.The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders.
Primary audience: Academic and industrial researchers, bioprocess engineers, chemical and biochemical engineers. Graduate students and academics working in the area of Stem Cells and as a teaching book. Secondary: Chemists, biochemists and biologists working on stem cell research would also be interested in this book
1. Genetic Engineering in Stem Cell Manufacturing
2. Biomechanics in Stem Cell Manufacturing
3. Bioreactor Engineering Fundamentals for Stem Cell Manufacturing
4. Microcarrier Culture Systems for Stem Cell Manufacturing
5. Novel Single-Use Bioreactors for Scale up of Anchorage-Dependent Cell Manufacturing for Cell Therapies
6. Bioreactors and Downstream Processing for Stem Cell Manufacturing
7. Cell production system based on flexible modular platform
8. Microfluidic Devices for the Culture of Stem Cells
9. Enrichment and Separation Technologies for Stem Cell-Based Therapies10. Expansion and Characterization Considerations for the Manufacturing of Stem Cells
11. Storage and Delivery of Stem Cells for Cellular Therapies12. Business Models for Manufacture of Cellular Therapies
13. Stem cells for the regeneration of chronic wounds: a translational perspective
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Dr. Cláudia Lobato da Silva is Assistant Professor at the Department of Bioengineering, IST-UTL, Lisboa, Portugal, and is co-author of 32 scientific articles published in international peer-reviewed journals and 4 book chapters. Her research interests include expansion of human stem cells, namely hematopoietic and mesenchymal stem cells, cellular therapies with human adult stem cells, isolation and purification of stem cells, and bioreactors for stem cell culture. At IST-UTL, Dr. Cláudia Lobato da Silva is the faculty responsible for the courses “Cell and Tissue Engineering” (since 2008/2009) and “Stem Cell Bioengineering” (since 2010/2011), whose attendees include MSc students in Biological Engineering and Biomedical Engineering. Recently, Dr. Cláudia Lobato da Silva was appointed as Associate Editor of BMC Biotechnology.
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