Nanobiomaterials in Medical Imaging

Applications of Nanobiomaterials

1st Edition - April 13, 2016
Editor: Alexandru Grumezescu
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 4 1 7 3 6 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 4 1 7 3 8 - 9

Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss r… Read more

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Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques.

The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered.

This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.

List of contributors
Preface of the series
Preface
- About the Series (Volumes I–XI)
- About Volume VIII
Chapter 1. Specifically targeted imaging using functionalized nanoparticles
- Abstract
- 1.1 Introduction
- 1.2 Functionalized Quantum Dots for Imaging
- 1.3 Functionalized Iron Oxide Nanoparticles for Imaging
- 1.4 Functionalized Silver Nanoparticles for Imaging
- 1.5 Conclusions
- References
Chapter 2. Photon and electron interactions with gold nanoparticles: A Monte Carlo study on gold nanoparticle-enhanced radiotherapy
- Abstract
- 2.1 Introduction
- 2.2 Gold Nanoparticle-Enhanced Radiotherapy
- 2.3 Monte Carlo Simulation
- 2.4 Photon and Electron Interactions
- 2.5 Conclusions
- Acknowledgments
- References
Chapter 3. Quantum dots: Dynamic tools in cancer nanomedicine
- Abstract
- 3.1 Introduction
- 3.2 Characteristic Features of Quantum Dots
- 3.3 Composition of Quantum Dots
- 3.4 Architecture of Multifunctional Quantum Dots
- 3.5 Synthesis and Functionalization of QDs
- 3.6 Quantum Dots in Cancer Therapy
- 3.7 Quantum-Dot-Based Photodynamic Therapy (PDT)
- 3.8 Toxicity Concerns
- 3.9 Future Prospects
- 3.10 Conclusions
- References
Chapter 4. Basics to different imaging techniques, different nanobiomaterials for image enhancement
- Abstract
- 4.1 Introduction
- 4.2 Basics of Different Imaging Techniques
- 4.3 Imaging Agents
- 4.4 Different Nanobiomaterials for Image Enhancement
- 4.5 Miscellaneous
- 4.6 Conclusions and Outlook
- References
Chapter 5. Design of plasmonic probes through bioconjugation and their applications in biomedicine: From cellular imaging to cancer therapy
- Abstract
- 5.1 Introduction
- 5.2 Optical Properties of Metal Nanoparticles
- 5.3 Synthesis and Functionalization of Plasmonic Nanoparticles
- 5.4 Applications in Biomedicine
- 5.5 Conclusions
- Acknowledgments
- References
Chapter 6. Multifunctional nanocarriers for codelivery of nucleic acids and chemotherapeutics to cancer cells
- Abstract
- 6.1 Introduction
- 6.2 Design of Multifunctional Delivery Systems for Drug–Gene Coadministration
- 6.3 Multifunctional Nanomaterials for Codelivery of Drug–Nucleic Acid Combinations
- 6.4 Conclusions and Future Perspectives
- References
Chapter 7. Targeting and imaging of cancer cells using nanomaterials
- Abstract
- 7.1 Introduction
- 7.2 Quantum Dots
- 7.3 Dendrimers
- 7.4 Magnetic Nanoparticles (MNPs)
- 7.5 Colloidal Gold Nanoparticles
- 7.6 Carbon-Based Nanomaterials
- 7.7 Liposomal Nanocarriers
- 7.8 Conclusions and Future Directions
- References
Chapter 8. Multimodal inorganic nanoparticles for biomedical applications
- Abstract
- 8.1 Introduction
- 8.2 Types of Multimodal Inorganic Nanoparticles
- 8.3 Toxicological Considerations and Surface Modification of Multimodal Inorganic Nanoparticles
- 8.4 Biomedical Applications of Multimodal Inorganic Nanoparticles
- 8.5 Summary and Future Outlook
- Acknowledgments
- References
Chapter 9. Iron oxide nanomaterials for functional imaging
- Abstract
- 9.1 Introduction
- 9.2 Iron Oxide Nanoparticles as Contrast Agents in Noninvasive Imaging Diagnosis
- 9.3 Functionalized Iron Oxide Nanoparticles for Imaging Diagnosis
- 9.4 Conclusions
- References
Chapter 10. Nanobiomaterials involved in medical imaging technologies
- Abstract
- 10.1 Introduction
- 10.2 Medical Imaging Technology
- 10.3 Nanobiomaterials in Medical Imaging
- 10.4 Conclusions
- References
Chapter 11. Applications of carbon dots in biosensing and cellular imaging
- Abstract
- 11.1 Introduction
- 11.2 CDs as Fluorescent Probes for Sensing of Biomolecules
- 11.3 CDs as Fluorescent Probes for Imaging of Biomolecules and Cells
- 11.4 Conclusions and Perspectives
- References
Chapter 12. Inorganic nanobiomaterials for medical imaging
- Abstract
- 12.1 Introduction
- 12.2 Solid Silica Nanoparticles (SNPs)
- 12.3 Gold Nanoparticles (AuNPs)
- 12.4 Iron Oxide Nanoparticles
- 12.5 Quantum Dots (QDs)
- 12.6 Conclusions
- References
Chapter 13. Nanobiomaterials in X-ray luminescence computed tomography (XLCT) imaging
- Abstract
- 13.1 Introduction
- 13.2 XLCT Imaging System
- 13.3 XLCT Reconstruction Methods
- 13.4 Future Directions in XLCT
- 13.5 Conclusions
- Acknowledgments
- References
Chapter 14. Multifunctional carbon nanotubes in cancer therapy and imaging
- Abstract
- 14.1 Introduction
- 14.2 Carbon Nanotubes
- 14.3 Transcellular Trafficking Mechanism of f-CNTs
- 14.4 CNTs in Cancer Therapy
- 14.5 CNTs in Imaging
- 14.6 Conclusions
- Acknowledgments
- References
Chapter 15. Functionalized carbon nanotubes and their promising applications in therapeutics and diagnostics
- Abstract
- 15.1 Introduction
- 15.2 Origin and Historical Perspective of CNT
- 15.3 Classification of CNTs
- 15.4 Methods for Preparation of CNTs
- 15.5 Functionalization of CNTs
- 15.6 Characterization of CNTs
- 15.7 Cellular Trafficking of CNTs
- 15.8 Applications of CNTs
- 15.9 Role of CNTs in Diagnostics
- 15.10 Toxicity Consideration of CNTs
- 15.11 Biodistribution of CNTs
- 15.12 Regulatory Considerations
- 15.13 Conclusions
- References
Index

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Alexandru Grumezescu