Molecular Biology, 2nd Edition,David Clark,Nanette Pazdernik,ISBN9780123785947
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Molecular Biology, 2nd Edition

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Imprint: ACACL

ISBN: 9780123785947

Pages: 928

Dimensions: 276 X 216

The second edition of Clark and Pazdernik’s Molecular Biology examines the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers.

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Key Features

  • NEW: "Focus On Relevant Research" sections integrate primary literature from Cell Press and focus on helping the student learn how to read and understand research to prepare them for the scientific world.
  • NEW: Academic Cell Study Guide features all articles from the text with concurrent case studies to help students build foundations in the content while allowing them to make the appropriate connections to the text.
  • NEW: Animations provided include topics in protein purification, transcription, splicing reactions, cell division and DNA replication and SDS-PAGE
  • Updated chapters on Genomics and Systems Biology, Proteomics, Bacterial Genetics and Molecular Evolution and RNA
  • Updated ancillary package includes flashcards, online self quizzing, references with links to outside content and PowerPoint slides with images.
  • Fully revised art program

Description

The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. The second edition of Molecular Biology, winner of a 2013 Texty Award from the Text and Academic Authors Association, reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. This volume effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community.

Readership

Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture

David Clark

BA (honors)Christ's College Cambridge, 1973 PhD University of Brsitol (England), 1977

Dr. Clark has taught courses in Molecular Biology and Bacterial Physiology and Biochemistry at Southern Illinois University since 1981. Research into the Regulation of Alcohol Fermentation in E. coli has been funded by the U.S. Department of Energy, Office of Basic Energy Sciences from 1982 till present. Supervised 11 master’s and 7 PhD students Published approximately 70 articles in scientific journals Previously published work includes "Molecular Biology Made Simple and Fun" coauthored with Lonnie Russell. (Cache River Press, Vienna, IL, First edition, 1997 and Second edition, 2000)

Affiliations and Expertise

Southern Illinois University, Carbondale, Illinois, USA

View additional works by David P. Clark

Nanette Pazdernik

Affiliations and Expertise

School of Medicine at Washington University, St. Louis, Missouri, USA

View additional works by Nanette J. Pazdernik

Molecular Biology, 2nd Edition

Unit 1: Basic Chemical and Biological Principles

Ch1 Cells and Organisms

Ch2 Basic Genetics

Ch3 DNA, RNA, and Protein

Ch4 Genes, Genomes, and DNA

Ch5 Manipulation of Nucleic Acids

Unit 2: The Genome

Ch6 Polymerase Chain Reaction

Ch7 Cloning Genes for Analysis

Ch8 DNA Sequencing

Ch9 Genomics & Systems Biology

Unit 3: The Central Dogma of Molecular Biology

Ch10 Cell Division and DNA Replication

Ch11 Transcription of Genes

Ch12 Processing of RNA

Ch13 Protein Synthesis

Ch14 Protein Structure & Function

Ch15 Proteomics: Global Analysis of Proteins

Unit 4: Regulating Gene Expression

Ch16 Regulation of Transcription in Prokaryotes

Ch17 Regulation of Transcription in Eukaryotes

Ch18 Regulation at RNA Level

Ch19 Analysis of Gene Expression (Transcriptome)

Unit 5: Subcellular Life Forms

Ch20 Plasmids

Ch21 Viruses

Ch22 Mobile DNA

Unit 6: Changing the DNA Blueprint

Ch23 Mutations and Repair

Ch24 Recombination

Ch25 Bacterial Genetics

Ch26 Molecular Evolution

Quotes and reviews

"This book reflects the massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves."--ANTICANCER RESEARCH 33: 745-746 (2013), February 2013
"This comprehensive text gives students and researchers a sound and practical knowledge of molecular biology. Consisting of 28 lucidly written chapters, this book presents basic concepts, recent updates, methodological principles and applications in this central biology discipline. The authors have adopted an interesting pedagogic approach to ensure smooth delivery of the presented information. This involved the use of nicely-designed meaningful illustrations, highlighting key concepts in each chapter, and raising review and conceptual questions. There is also a novel feature of ‘Focus on Relevant Research’ sections relating pertinent research articles to key concepts in the text. These sections illustrate how the development of frontier research in molecular biology is based upon the proper understanding of its prime concepts. This second edition of the text is accompanied by an online study guide, which contains useful material including review questions, and references to relevant articles. I would highly recommend this informative, well-presented book to students and researchers seeking sound and practical updated knowledge in molecular biology."--
Science Progress

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Molecular Biology