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The EGF Receptor Family

Biologic Mechanisms and Role in Cancer

  • 1st Edition - December 19, 2003
  • Editor: Graham Carpenter
  • Language: English
  • eBook ISBN:
    9 7 8 - 0 - 0 8 - 0 4 7 2 5 8 - 4

The enormity of the literature on growth factors, plus the breadth of the biological disciplines and technical expertise required prohibits a comprehensive review by even a… Read more

The EGF Receptor Family

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The enormity of the literature on growth factors, plus the breadth of the biological disciplines and technical expertise required prohibits a comprehensive review by even a multi-disciplinary panel of authors. To provide an alternative that is feasible for authors and digestible by readers, this review compendium consists of a collection of articles, each covering an aspect of teh ErbB/EGF field. This compilation features articles on growth factor ligands, neuregulins, and individual receptors. The second part of the book concentrates on the biological context of the ErbB receptors, particularly in mammary development and in cancer. It concludes with a discussion of the genetic systems that have enabled significant advances in research in this area.