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Linkage Thermodynamics of Macromolecular Interactions

  • 1st Edition, Volume 51 - May 20, 1998
  • Editors: Enrico Di Cera, Frederic M. Richards, David S. Eisenberg, Peter S. Kim
  • Language: English
  • Hardback ISBN:
    9 7 8 - 0 - 1 2 - 0 3 4 2 5 1 - 8
  • eBook ISBN:
    9 7 8 - 0 - 0 8 - 0 5 8 2 2 4 - 5

This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage… Read more

Linkage Thermodynamics of Macromolecular Interactions

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This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.