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The Human IgG Subclasses

Molecular Analysis of Structure, Function and Regulation

  • 1st Edition - October 15, 1990
  • Editor: Farouk Shakib
  • Language: English
  • eBook ISBN:
    9 7 8 - 1 - 4 8 3 2 - 8 7 2 0 - 1

This book features contributions from internationally renowned scientists from Europe and the USA covering aspects of immunoglobulin subclasses from a molecular and mechanistic… Read more

The Human IgG Subclasses

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This book features contributions from internationally renowned scientists from Europe and the USA covering aspects of immunoglobulin subclasses from a molecular and mechanistic approach. The first section presents a detailed discussion of the molecular structure and segmental flexibility of IgG subclasses, including how this controls their effector function. Structure-function relationships are fully developed in the second section by means of a functional approach to the study of complement activation and opsonization by IgG subclasses. The final section contains a generous account of the regulation of IgG subclass expressions.