PART I: MOLECULAR IMAGING
1. Fluorine-18 Chemistry for Molecular Imaging with Positron Emission Tomography
Frédéric Dollé, Dirk Roeda, Bertrand Kuhnast, and Marie-Claire Lasne
2. Application of 18F-PET Imaging for the Study of Alzheimer’s Disease
Kjell Någren and Juha O. Rinne
3. 18F-Labeled PET-Tracers for Cardiological Imaging
Klaus Kopka, Stefan Wagner, Michael Schäfers, Andreas Faust, Otmar Schober, and Günter Haufe
4. [18F]-Labeled PET and PET/CT Compounds in Oncology
Ken Herrmann and Bernd Joachim Krause
5. Non-Invasive Physiology and Pharmacology Using 19F Magnetic Resonance
Jian-Xin Yu, Weina Cui, Dawen Zhao, and Ralph P. Mason
PART II: BIOMEDICAL MATERIALS
6. Fluoride-Based Bioceramics
Christian Rey, Christèle Combes, Christophe Drouet, and Hocine Sfihi
7. Fluoride in Dentistry and Dental Restoratives
John W. Nicholson and Beata Czarnecka
8. Fluorinated Biomaterials for Cardiovascular Surgery
Charles Baquey, Marie-Christine Durrieu, and Robert G. Guidoin
9. Fluorinated Molecules in Eye Surgery: Experimental and Clinical Benefit of a Heavy Silicone Oil Oxane Hd® (Mixture of Silicone Oil and RMN3 Fluorine Olefin) in the Treatment of Retinal Detachment
I. Rico-Lattes, J. C. Quintyn, V. Pagot-Mathis, X. Benouaich, and A. Mathis
10. Biocompatibility of Highly Fluorinated Liquids Used in Ophthalmic Surgery
Dirk-Henning Menz and Joachim H. Dresp
11. Perfluorochemical-Based Oxygen Therapeutics, Contrast Agents, and Beyond
Marie Pierre Krafft and Jean G. Riess
12. Exposure of Humans to Fluorine and Its Assessment
Maja Ponikvar
PART III: PHARMACEUTICALS
13. Biological Impacts of Fluorination: Pharmaceuticals Based on Natural Products
Jean-Pierre Bégué and Danièle Bonnet-Delpon
14. Synthesis and Pharmacological Properties of Fluorinated Prostanoids
Yasushi Matsumura
15. Synthesis and Biochemical Evaluation of Fluorinated Monoamine Oxidase Inhibitors
Kenneth L. Kirk, Shinichi Yoshida, and Günter Haufe
16. Fluoroolefin Dipeptide Isosteres: Structure, Syntheses, and Applications
John T. Welch
17. Molecular Interactions of Fluorinated Amino Acids in a Native Polypeptide Environment
Mario Salwiczek, Christian Jäckel, and Beate Koksch
18. Biological Fluorination in Streptomyces cattleya: The Fluorinase
Hai Deng, Fang-Lu Huang, James H. Naismith, David O′Hagan, Jonathan B. Spencer, and Xiaofeng Zhu