Co Editors-in-Chief::A.J. van Wijnen





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Aims & Scope

Gene publishes papers that focus on the regulation, expression, function and evolution of genes in all biological contexts, including all prokaryotic and eukaryotic organisms, as well as viruses.

Gene strives to be a very diverse journal and topics in all fields will be considered for publication. Although not limited to the following, some general topics include:

• DNA Organization, Replication & Evolution -Focus on genomic DNA (chromosomal organization, comparative genomics, DNA replication, DNA repair, mobile DNA, mitochondrial DNA, chloroplast DNA).
• Expression & Function - Focus on functional RNAs (microRNAs, tRNAs, rRNAs, mRNA splicing, alternative polyadenylation)
• Regulation - Focus on processes that mediate gene-read out (epigenetics, chromatin, histone code, transcription, translation, protein degradation).
• Cell Signaling - Focus on mechanisms that control information flow into the nucleus to control gene expression (kinase and phosphatase pathways controlled by extra-cellular ligands, Wnt, Notch, TGFbeta/BMPs, FGFs, IGFs etc.)
• Profiling of gene expression and genetic variation - Focus on high throughput approaches (e.g., DeepSeq, ChIP-Seq, Affymetrix microarrays, proteomics) that define gene regulatory circuitry, molecular pathways and protein/protein networks.
• Genetics - Focus on development in model organisms (e.g., mouse, frog, fruit fly, worm), human genetic variation, population genetics, as well as agricultural and veterinary genetics.
• Molecular Pathology & Regenerative Medicine - Focus on the deregulation of molecular processes in human diseases and mechanisms supporting regeneration of tissues through pluripotent or multipotent stem cells.

Gene encourages submission of novel manuscripts that present a reasonable level of analysis, functional relevance and/or mechanistic insight. Gene also welcomes papers that have predominantly a descriptive component but improve the essential basis of knowledge for subsequent functional studies, or provide important confirmation of recently published discoveries.

The primary criteria for acceptance are that the work is original and scientifically sound. The journal appreciates that standards of novelty are arbitrary, differ among disciplines and geographic locations, as well as change with time. In partnership with Editors, Referees and Authors, the journal will promote the revision of papers to ensure that accepted papers are reasonably complete and competitive with concurrent submissions in a given field.


Molecular biologists, geneticists, biotechnologists

Abstracting and Indexing

BIOSIS, Chemical Abstracts, Current Contents/Life Sciences, EMBASE, EMBiology, MEDLINE®, Pascal et Francis (INST-CNRS), Reference Update, Science Citation Index, Scopus
Editor-in-Chief: A.J. van Wijnen Dept. of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA, Scientific Editor M. Jendrysik Elsevier Inc., 600 Technology Square, Cambridge, MA 02139, USA, Founding/Honorary Editor: W. Szybalski University of Winconsin Medical School, Madison, WI, USA, Executive Editors: S. Cool Inst. of Medical Biology, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove; #06-06 Immunos, 138648 Singapore, Singapore, R. Cordaux UMR CNRS 6556, Ecologie Evolution Symbiose, Université de Poitiers, 40 avenue du Recteur Pineau, 86022 Poitiers, France, J.-M. Deragon Lab. Génome et Développement des Plantes (LGDP), UMR5096 CNRS/UPVD, Université de Perpignan, 58, avenue Paul Alduy, 66860 Perpignan, France, A.M. Engel Dept. of Epidemiology, Tulane Cancer Center, Tulane University, 1430 Tulane Avenue, New Orleans, LA 70112-2699, USA, T. Gojobori Ctr. for Information Biology, National Institute of Genetics, 1111 Yata, 411-8540 Mishima, Shizuoka, Japan, B. Keats Research School of Biological Sciences, Australian National University (ANU), Canberra, ACT 0200, Australia, M. Montecino Dept. de Biologia Molecular, Fac. de Ciencias Biologicas, Universidad de Concepción, Casilla 160-C, Concepcion, Chile, A. Rynditch Dept. of Molecular Oncogenetics, Inst. of Molecular Biology and Genetics, Ukrainian National Academy of Sciences (NAS), 150 Zabolotnogo str., 03143 Kiev, Ukraine, M. Schartl Biocenter, Physiologische Chemie I, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg, Germany, S. Stifani Montreal Neurological Inst., McGill University, 3801 rue University, Montreal, H3A 2B4, Canada, A. Su Dept. of Molecular & Experimental Medicine & Immunology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037-1000, USA, G. Theißen Lehrstuhl für Genetika, Friedrich-Schiller-Universität Jena, Philosophenweg 12, 07743 Jena, Germany, J.P.T.M. van Leeuwen Dept. of Internal Medicine, Erasmus MC: Universitair Medisch Centrum Rotterdam, Dr Molenwaterplein 50, 3015 GE Rotterdam, Netherlands, C. Vieira-Heddi Bât. Grégor Mendel, UMR CNRS 5558 - LBBE, Université Claude Bernard - Lyon I, 43 bd du 11 novembre 1918, 69622 Villeurbanne, France, J.J. Westendorf Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA, Editorial Board M.L. Allende Santiago, Chile, S. Arhondakis Athens, Greece, K. Blyth Glasgow, UK, H. E. Boudreau Bethesda, MD, USA, A. Canario Faro, Portugal, A. Charest Boston, MA, USA, S. Chuva de Sousa Lopes Leiden, Netherlands, O. Coqueret Angers, France, J. Davie Winnipeg, MB, Canada, D. Doenecke Gottingen, Germany, R.J. Duronio Chapel Hill, NC, USA, J. M. Enserink Oslo, Norway, M. Galindo Santiago, Chile, X. Graña Philadelphia, PA, USA, M. F. Hansen Farmington, CT, USA, J. R. Hawse Rochester, MN, USA, S.W. Herke Baton Rouge, LA, USA, R. Herrera Miami, FL, USA, E. Hesse Boston, MA, USA, M. Hurley Farminghton, CT, USA, T. Ip Worcester, MA, USA, K. Ito Nagasaki, Japan, I. Kalajzic Farmington, CT, USA, A. Keller Würzburg, Germany, S. Kikuchi Tsukuba, Ibaraki, Japan, P. Kloen AZ, Amsterdam, Netherlands, D. A. Kramerov Moscow, Russian Federation, C. J. Lengner Philadelphia, PA, USA, D. T. Leong Singapore, Singapore, C. LePoole Maywood, IL, USA, L. Ling Singapore, Singapore, Y. Loh Cambridge, MA, USA, P. J. Marie Paris, France, L. Mariño-Ramírez Bethesda, MD, USA, E. Martinez Riverside, CA, USA, W.F. Marzluff Chapel Hill, NC, USA, T. A. McCaffrey Washington, DC, USA, L. McCauley Ann Arbor, MI, USA, E. Mirkin Cambridge, MA, USA, D.L. Mykles Fort Collins, CO, USA, S. Nathan Singapore, Singapore, J. Neil Glasgow, UK, A. Nepveu Montreal, QC, Canada, N. Normanno Naples, Italy, M. Osato Singapore, Singapore, C. Perez Santiago 7, Chile, S. Pervaiz Singapore, Singapore, M. Plohl Zagreb, Croatia, J. N. Post Enschede, Netherlands, J. Pratap Chicago, IL, USA, S. V. Razin Moscow, Russian Federation, I. T. Rebustini Boston, USA, A.P. Rooney Peoria, IL, USA, H.-M. Ryoo Jung-Gu, Dae-gu, South Korea, H. I. Sampen Chicago, IL, USA, E. Seto Tampa, FL, USA, M.B. Soares Chicago, IL, USA, S. Song Beijing, China, J. Squire Kingston, Canada, R. St. Arnaud Montreal, QC, Canada, Y.&
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