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Amino Acids, Proteins and Cancer Biochemistry
1st Edition - January 1, 1960
Author: Jesse P. Greenstein
Editor: John T. Edsall
Language: English
eBook ISBN:9781483270531
9 7 8 - 1 - 4 8 3 2 - 7 0 5 3 - 1
Amino Acids, Proteins, and Cancer Biochemistry focuses on the contributions of Jesse P. Greenstein to biological chemistry, including kinetics, protein mixtures, metabolism,…Read more
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Amino Acids, Proteins, and Cancer Biochemistry focuses on the contributions of Jesse P. Greenstein to biological chemistry, including kinetics, protein mixtures, metabolism, tumors, and biosynthesis. The selection first offers information on quantitative nutritional and in vivo metabolic studies with water-soluble, chemically defined diets and internal hydrogen bonding in ribonuclease. Discussions focus on the effects of deuterium on transition temperature, kinetics of deuterium-hydrogen exchange, applications of chemically denned diets, formulation of water-soluble, chemically defined diets, and large-scale preparation of optically pure amino acids. The manuscript then examines the chromatographic evaluation of protein mixtures and observations on the activation of amino acids and biosynthesis of peptide bonds, including synthesis of phenylacetylglutamine and benzoylglycine, studies on amino acyl adenylates, and synthesis of glutamine. The publication ponders on free amino acids and related substances in normal and neoplastic tissues; nucleic acids of normal tissues and tumors; and carbohydrate metabolism in ascites tumor and HeLa cells. Topics include carbohydrate metabolism of ascites tumor cells, comparative biochemistry of glycolysis, DNA and the genetic concept of cancer, and constancy of free amino acid patterns of tissues. The selection is a valuable source of data for biochemists and researchers interested in amino acids, proteins, and cancer biochemistry.
ContributorsPrefaceJesse Philip Greenstein, 1902-1959Quantitative Nutritional and In Vivo Metabolic Studies with Water-Soluble, Chemically Defined DietsInternal Hydrogen Bonding in RibonucleaseConsiderations of the Structure and Function of Carboxypeptidase AChromatographic Evaluation of Protein MixturesObservations on the Activation of Amino Acids and the Biosynthesis of Peptide BondsEnzyme Activities and Tumor ProgressionFree Amino Acids and Related Substances in Normal and Neoplastic TissuesThe Nucleic Acids of Normal Tissues and TumorsCarbohydrate Metabolism in Ascites Tumor and HeLa CellsA Digital Computer Representation of Chemical and Spectroscopic Studies on Chemical Control of Ascites Tumor Cell MetabolismBibliography of the Published Work of Jesse P. GreensteinAuthor IndexSubject Index
No. of pages: 254
Language: English
Edition: 1
Published: January 1, 1960
Imprint: Academic Press
eBook ISBN: 9781483270531
JE
John T. Edsall
Affiliations and expertise
Biological Laboratories
Harvard University
Cambridge, Massachusetts
JG
Jesse P. Greenstein
Affiliations and expertise
National Cancer Institute, US. Public HealthService, Bethesdu, Maryland
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