Laboratory Investigation of Endocrine Disorders

2nd Edition - May 17, 1983
Authors: Michael R. Wills, Bill Havard
Language: English
eBook ISBN:
9 7 8 - 1 - 4 8 3 1 - 8 2 6 0 - 5

Laboratory Investigation of Endocrine Disorders, Second Edition serves as a basic guide to the available endocrine laboratory tests. This book discusses the developments in the… Read more

Purchase options

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

Laboratory Investigation of Endocrine Disorders, Second Edition serves as a basic guide to the available endocrine laboratory tests. This book discusses the developments in the understanding of the mechanisms involved in the pathogenesis of endocrine disorders. Organized into 9 chapters, this edition begins with an overview of the control of thyroid hormone secretion. This text then explains the role of hypothalamus in the control of the activities of the functionally distinct anterior and posterior lobes of the pituitary gland. Other chapters consider the disorders of calcium homeostasis and their investigation with specific reference to hypocalcemia and hypercalcemia. This book discusses as well the adrenal cortical function. The final chapter deals with the normal steady-state regulation of calcium, which includes diet, physiological mechanisms, and hormones. This book is a valuable resource for laboratory-based scientists, both the medical and the non-medical. Senior clinical students and medical practitioners will also find this book useful.

1. Thyroid Disorders Physiology Specimens and Normal Range Values Total Serum Thyroxine (T4) Total Serum Tri-Iodothyronine (T3) Free Binding Capacity (FBC) Free Thyroxine Index (FTI) Thyrotrophin (TSH) In Vivo Tests 99mTc Uptake Thyroid Scan Thyrotrophin-Releasing Hormone (TRH) Test Other Tests Thyroid Antibodies in Thyroiditis Thyroid-Stimulating Antibodies (TSAB) Cholesterol Diagnostic Considerations Hypothyroidism Hyperthyroidism Investigation of Thyroid Status in Patients after Treatment of Hyperthyroidism Investigation of Thyroid Status in Patients after Treatment of Hypothyroidism 2. Hypothalamic-Anterior Pituitary Disorders Physiology Specimens and Normal Range Values Growth Hormone Follicle-Stimulating and Luteinizing Hormones Prolactin Adrenocorticotrophin Dynamic Tests LH-RH Test Combined Test Diagnostic Considerations Hypopituitarism Growth Hormone Excess Galactorrhoea Precocious Puberty3. Hypothalamic-Pituitary-Adrenocortical Axis Physiology Specimens and Normal Range Values Plasma Cortisol Urine for Steroids Normal Range Values Dynamic Tests Tetracosactrin Dexamethasone Suppression Tests Metyrapone Test Diagnostic Considerations Adrenocortical Hyperplasia (Cushing's Syndrome) Adrenocortical Hypofunction4. Hypothalamic-Posterior Pituitary Disorders Physiology Specimens and Normal Range Values Diagnostic Considerations Diabetes Insipidus Inappropriate ADH Syndrome5. Adrenal Cortical Disorders Physiology Specimens and Normal Range Values Plasma Cortisol Plasma Renin and Aldosterone Plasma 17-α-Hydroxyprogesterone Urine Pregnanetriol Urine 11-Oxygénation Index Diagnostic Considerations Primary Adrenocortical Hypofunction (Addison's Disease) Secondary Adrenocortical Hypofunction Congenital Adrenal Hyperplasia Primary Hyperaldosteronism (Conn's Syndrome) Secondary Hyperaldosteronism Hypoaldosteronism6. Disorders of the Adrenal Medulla Physiology Specimens and Normal Range Values Plasma Urine Diagnostic Considerations Phaeochromocytoma7. Ovarian Disorders Physiology Gametogenesis Secretion of Oestrogens Specimens and Normal Range Values Oestradiol-17-ß Progesterone Pregnanediol Urine Total Oestrogens in the Non-Pregnant Urine Total Oestrogens in Pregnancy Dynamic Tests Clomiphene Stimulation Test LH-RH Test Human Menopausal Gonadotrophin Stimulation Clinical Considerations Amenorrhoea Infertility Hyperprolactinaemic Hypogonadism Precocious Puberty Hirsuties and Virilism8. Testicular Disorders Physiology Specimens and Normal Range Values Plasma LH and FSH Plasma Testosterone Urine 17-Oxosteroids Dynamic Tests Clomiphene Stimulation Test HCG Stimulation Test Diagnostic Considerations Infertility Hypogonadism Precocious Puberty9. Disorders of Calcium Homeostasis Physiology Specimens and Normal Range Values Calcium (Total) Calcium (Ionized) Plasma Phosphorus Phosphate Excretion Tests Magnesium Serum Proteins and Albumin Alkaline Phosphatase Parathyroid Hormone 25-Hydroxyvitamin D and 1,25 Dihydroxycholecalciferol Calcitonin Urine Calcium Urine Hydroxyproline Urine Cyclic AMP Dynamic Tests Cortisone Suppression Test Diagnostic Considerations Hypercalcaemia HypocalcaemiaAppendix Normal Reference Values and Factors for the Conversion of Conventional to Si Units