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Chemistry, Biochemistry, and Pharmacological Activity of Prostanoids
Including the Proceedings of a Symposium on the Chemistry and Biochemistry of Prostanoids Held at The University of Salford, England, 10-14 July 1978
1st Edition - January 1, 1979
Editors: Stanley M. Roberts, Feodor Scheinmann
Language: English
eBook ISBN:9781483146034
9 7 8 - 1 - 4 8 3 1 - 4 6 0 3 - 4
Chemistry, Biochemistry, and Pharmacological Activity of Prostanoids contains the proceedings of a symposium on the Chemistry and Biochemistry of Prostanoids held at the University…Read more
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Chemistry, Biochemistry, and Pharmacological Activity of Prostanoids contains the proceedings of a symposium on the Chemistry and Biochemistry of Prostanoids held at the University of Salford, England on July 10-14, 1978. Separating 29 papers of the symposium as chapters, this book begins with a description of prostanoids in health and disease and recent developments in the synthesis of antisecretory prostaglandins. Other topics discuss synthesis of some novel 11-deoxyprostaglandins; bicycles, tricycles and prostaglandin synthesis; chemical and biological studies on new prostanoids; and isolation and characterization of enzymes involved in prostaglandin biosynthesis. Structure activity relationships of prostaglandins and a biochemical background of caloric restriction therapy of obesity are also explained.
Contents
Preface,Introduction to Nomenclature,and Acknowledgments
Prostanoids in Health and Disease
Recent Developments in the Synthesis of Antisecretary Prostaglandins
Synthesis of Some Novel 11-Deoxyprostaglandins
Synthesis and Bronchial Dilator Activity of Some Novel Prostaglandin Analogues
Bicycles, Tricycles and Prostaglandin Synthesis
The Total Synthesis of(±)Prostaglandin
Chemical and Biological Studies on New Prostanoids
A Method for the Inversion of Configuration of Alcohols
The Synthesis of Compounds Formed in the Arachidonic Acid
Cascade and Agents Which Modulate their Production
On the Existence of the Existence of 6(9α)-Oxido-11α,15(S)-dihydroxyprosta-7(8),(E)13-dienoic Acid
Novel Metabolite of Arachidonic Acid
Bicyclo[3,2,0] heptan-2-ones; a Photochemical Route to Prostanoid Synthons
The Synthesis of Cyclopentenolone Precursors to Prostaglandins from Furan Derivatives
A General Synthesis of the Prostaglandins from Butadiene and Levulinic Acid
A New Stereoselective Synthesis of Prostaglandins
Biologically Active 11-Deoxyprostaglandins
Thromboxane-like Activity of Prostanoids with Aromatic Substituents at C-16 and C-17
Biosynthesis of Prostaglandins and Thromboxanes
Isolation and Chracterization of Enzymes involved in Prostaglandin Biosynthesis
15-Deoxy-16-hydroxyprostaglandins.Synthesis and Bronchodilator Activity
Prostacyclin Formation and Effects
Synthesis and Stereochemistry of Stable Prostacyclin Analogues
Synthesis and Biological Properties of Prostacyclins and Prostaglandin Endoperoxide Analogs
The 6(9)Oxy Cyclase Pathway of Prostaglandin Endoperoxide Metabolism
The Gastric Antisecretory Properties of Some Prostaglandin Analogues
Structure Activity Relationships of Prostaglandins
The Cleavage of Silyloxy-groups by Boron Trifluoride Etherate
15-Deoxy-16-hydroxy-PGE1 Carbinols. Synthesis and Biological Activity
A Biochemical Background of Calory Restriction Therapy of Obesity: Lipid Peroxide Mobilization
The Synthesis and Biological Properties of 9α,11α-Trithiocarbonate of 9α,llα-Bisdeoxy-PGF2. A Mimic of Prostaglandin Endoperoxide
Author Index
Subject Index
No. of pages: 420
Language: English
Edition: 1
Published: January 1, 1979
Imprint: Pergamon
eBook ISBN: 9781483146034
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