Assessing Nanoparticle Risks to Human Health

Assessing Nanoparticle Risks to Human Health, 1st Edition

Assessing Nanoparticle Risks to Human Health, 1st Edition,Gurumurthy Ramachandran,ISBN9781437778632


G Ramachandran   

William Andrew

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The book will take a systematic look at nanoparticle risks within the paradigm of risk assessment, consider the limitations of this paradigm in dealing with the extreme uncertainties regarding many aspects of nanoparticle exposure and toxicity, and suggest new methods for assessing and managing risks in this context. It will consider the occupational environment where the potential for human exposure is the greatest as well as the issues relevant to occupational exposure assessment (e.g., the exposure metric) and the evidence from toxicological and epidemiological studies.

A chapter will be devoted to how conventional risk assessment can be carried out for a candidate nanoparticle (e.g., carbon nanotubes), and the limitations that arise from this approach. We will propose several alternate methods in another chapter including screening assessments and adapting the rich methodological literature on the use of experts for risk assessment. Another chapter will deal with non-occupational populations, their susceptibilities, and life-cycle risk assessments. There will be a chapter on current risk management and regulatory oversight frameworks and their adequacy. This chapter will also include a discussion of U.S. and E.U. approaches to risk assessment, as well as corporate approaches.

Gurumurthy Ramachandran

Gurumurthy Ramachandran is a Professor in the Division of Environmental Health Sciences, University of Minnesota, USA

Affiliations and Expertise

Division of Environmental Health Sciences, University of Minnesota, USA

Assessing Nanoparticle Risks to Human Health, 1st Edition

  1. Introduction
  2. Assessing Exposures to Nanoparticles in the Occupational Environment
  3. Nanotoxicology and human health effects of Nanoparticles
  4. Risk Assessment Case Study for Example Engineered Nanoparticles
  5. Using Expert Judgment for Risk Assessment
  6. Non-Occupational Population Risks and their Management
  7. Oversight and Regulation of Risks

Quotes and reviews

"This is a very thought-provoking and knowledgeable book for all those interested in how exposure risks may be assessed and managed, particularly of materials which are so widely used, but the safety of which, so little is known."--BTS Winter 2012, Issue 41, page 32-33


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