Description
Enantioselective synthetic methods are not only in the forefront of chemical and pharmaceutical research but activity in this area is constantly increasing. It is stimulated by the urgency to obtain drugs or compounds of medicinal interest as single anantiomers, and the keeness to synthesize natural products in nonracemic form. This volume presents seven chapters from pioneers and authorities in this rapidly expanding field.
Readership
For scientists and researchers in the field of asymmetric synthesis.
Advances in Asymmetric Synthesis, Volume 3, 1st Edition
Preface (A. Hassner).
Asymmetric synthesis of &Bgr;-amino acids and &Bgr;-lactum derivatives via cunjugate addition of metal amides (Y. Yamamoto
et al.).
Enantioselective deprotonation of cyclic ketones
(M. Majewski).
Stereoselective addition of chiral &agr;-aminoorganometallics to aldehydes (R.E. Gawley).
Asymmetric access to functional, structurally diverse molecules exploiting five-membered heterocyclic silyloxy dienes (G. Casiraghi
et al.).
Asymmetric catalysis using heterobimetallic compounds
(M. Shibasaki, H. Sasai).
Palladium-catalyzed enantioselective allylic substitution reactions (S.J. Sesay, J.M.J. Williams).
New achievements in asymmetric synthesis of organophosphorous compounds (O.I. Kolodiazhnyi).