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Brain Machine Interfaces
 
 

Brain Machine Interfaces, 1st Edition

Implications for Science, Clinical Practice and Society

 
Brain Machine Interfaces, 1st Edition,Jens Schouenborg,Martin Garwicz,Nils Danielsen,ISBN9780444538154
 
 
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Progress in Brain Research

Schouenborg   &   Garwicz   &   Danielsen   

Elsevier Science

9780444538154

9780444538161

296

235 X 191

Features contributions from pioneers and leading scientists in the field of BMI and motor systems physiology, including spinal cord, basal ganglia and motor cortex

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Key Features

  • Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Description

This volume follows on from the symposium "Brain Machine Interfaces - Implications for science, clinical practice and society", held on August 26th-29th 2010 in Ystad, Sweden, and features contributions from pioneers and leading scientists in the field of BMI and motor systems physiology, including spinal cord, basal ganglia and motor cortex. The wide range of topics covered include implants for mind control of prostheses and in robotics, clinical and experimental research on Deep Brain Stimulation (DBS) for the treatment of Parkinson’s disease, depression and Alzheimer’s disease, cochlear implants, retinal implants, novel flexible micro- and nano-electrode implants, safety aspects including acute and chronic tissue reactions to implants and on ethical issues in DBS. Program and abstracts from the individual contributors can be found on http://www.med.lu.se/nrc/bmi_symposium.

Readership

Neuroscientists, psychologists, neurologists

Jens Schouenborg

Affiliations and Expertise

Lund University, Sweden

Martin Garwicz

Affiliations and Expertise

Lund University, Sweden

Nils Danielsen

Affiliations and Expertise

Lund University, Sweden

Brain Machine Interfaces, 1st Edition

Series Editors

List of Contributors

Preface

Chapter 1: Making the lifetime connection between brain and machine for restoring and enhancing function

Introduction

Methods

Results

Discussion

Chapter 2: Out of the frying pan into the fire—the P300-based BCI faces real-world challenges

Introduction

P300

Classification

BCI applications

Influences on BCI performance

Nonvisual P300-based BCI systems

BCI faces the real-world challenge: user experiences with state-of-the-art technology

Conclusion

Chapter 3: Toward a whole-body neuroprosthetic

Introduction

Whole-body neuroprosthetic

BMI components

Large-scale neuronal recordings

BMI decoders

Bimanual control

Bipedal locomotion

Posture and balance

Functional electrical stimulation

Sensorized neuroprosthetic

A whole-body exoskeleton

Chapter 4: Biocompatible multichannel electrodes for long-term neurophysiological studies and clinical therapy—Novel concepts and design

The physiological state

State of the art

A widened concept of biocompatibility

Novel electrode constructs and implantation procedures

Concluding remarks

Chapter 5: Deep brain stimulation

Deep brain stimulation: A genuine brain-device interface

New brain electrode interfaces

Three-dimensional array of electrodes: 3D high-frequency stimulation for field shaping

From DBS to ECoG recording: Brain–machine interface neuroprosthetics for deficit compensation

Conclusion

Chapter 6: Deep brain stimulation

Introduction

Conclusion

Chapter 7: Development of neuromodulation treatments in a large animal model—Do neurosurgeons dream of electric pigs?

Introduction

The Göttingen minipig as a neurobiological research animal

Neuroimaging in the Göttingen minipig

Neurosurgery in the Göttingen minipig

Neural and stem cell transplantation in the Göttingen minipig

Deep brain stimulation in the Göttingen minipig

Spinal cord stimulation in the Göttingen minipig

Conclusion and perspectives

Chapter 8: A few examples of the contribution of animal research in rodents for clinical application of deep brain stimulation

Introduction

Nonmotor functions in PD

DBS for psychiatric disorders

General conclusion

Chapter 9: Cochlear implants

Introduction

Present-day cochlear implants

Importance of brain function in determining outcomes

A “top-down” or “cognitive neuroscience” approach to implant designs

Questions raised by the top-down approach

Chapter 10: Multimodal, longitudinal assessment of intracortical microstimulation

Introduction

Background

Experimental overview

Behavioral thresholds

Impedance

Histology

Conclusion and future work

Chapter 11: The functional consequences of chronic, physiologically effective intracortical microstimulation

Introduction

Methods

Results

Discussion

Chapter 12: Reducing surface area while maintaining implant penetrating profile lowers the brain foreign body response to chronically implanted planar silicon microelectrode arrays

Introduction

Methods

Results

Discussion

Conclusion

Chapter 13: Can histology solve the riddle of the nonfunctioning electrode?

General background

Implant size

Fixation mode

Functional distance

Implantation time

Implant size versus fixation mode over time

Relation between neurons and reactive cell capsule

Strategies for a tethered design

Conclusions

Chapter 14: Changes in CNS structures after spinal cord lesions

Reorganization of cortical areas after incomplete SCI

Reorganization of descending pathways after incomplete SCI

Changes in the spinal circuitry after SCI

Chapter 15: Modeling the potentiality of spinal-like circuitry for stabilization of a planar arm system

Introduction

Methods

Results

Discussion

Chapter 16: Advances in the use of electrical stimulation for the recovery of motor function

Introduction

Command channel for the MNP

Physiological-like electrical stimulation

Artificial control for MNPs: Cloning biological control

Sensor systems

Conclusions

Chapter 17: Intraspinal microstimulation for the recovery of function following spinal cord injury

Introduction

Use of intraspinal microstimulation for restoring leg movements

The movements recruited by ISMS

The stability of ISMS implants

Moving toward clinical application

Conclusions

Chapter 18: Interfacing neurons with carbon nanotubes:

Introduction

The biocompatibility of CNT-based substrates and the impact of CNTs on nerve cell signaling

CNTs as interfaces for neuronal stimulation and recording: improving electrode performance by CNTs

The impact of CNTs on neuronal morphology and growth

Conclusions

Chapter 19: Nanomodified surfaces and neurite outgrowth

Introduction

Methods

Results and discussion

Conclusions

Chapter 20: Direct local polymerization of poly(3,4-ethylenedioxythiophene) in rat cortex

Introduction

Materials and methods

Results and discussion

Conclusions

Subject Index

Volume in series

 
 
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