Biological Inorganic Chemistry

Biological Inorganic Chemistry, 2nd Edition

A New Introduction to Molecular Structure and Function

Biological Inorganic Chemistry, 2nd Edition,Robert Crichton,ISBN9780444537829






235 X 191

New revised edition of this bestseller, which teaches the importance of metals in biology, the environment and medicine.

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Key Features

  • Winner of a 2013 Textbook Excellence Awards (Texty) from the Text and Academic Authors Association
  • Readable style, complemented by anecdotes and footnotes
  • Enables the reader to more readily grasp the biological and clinical relevance of the subject
  • Color illustrations enable easy visualization of molecular mechanisms


The revised and expanded second edition of Biological Inorganic Chemistry, winner of a 2013 Texty Award from the Text and Academic Authors Association, presents an introduction to this exciting and dynamic field. An increasing understanding of the importance of metals in biology, the environment and medicine, and the multiple roles of metal ions in biological systems, has given rise to biological inorganic chemistry as a field of study.

The book begins with an overview of the concepts, both chemical and biological, required for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis, are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten, chromium and selected non-metals. The final five chapters provide a tantalizing view of the roles of metals in brain function, biomineralization, and a brief illustration of their importance in both medicine and the environment.


This book provides an ideal introduction for scientists studying the importance of metals in biology, medicine and environmental sciences and for students following courses in inorganic biochemistry, bioinorganic chemistry or inorganic chemistry. It is designed for:
  Researchers: Because it is clearly written and gives a homogeneous view of the subject Chemistry, biology, microbiology, plant science, medical research (preclinical and clinical) environmental research
  Students: Chemists / biologists following courses or taking an advanced topic in Inorganic chemistry, bioinorganic chemistry, biological inorganic chemistry. chemical biology, medicine and environmental sciences
  Consultants: To have access to important information collected in one volume. Pharmacological industry, foodstuffs and agro-industries, environmental applications

Robert Crichton

Unité de Biochimie, Université Catholique de Louvain, Louvain-la-Neuve, Belgium Prof. Crichton, originally from the UK, is well known in the inorganic biology community and is invited to speak at many international conferences. He has published 3 books in this area (others on biochemistry of iron and metal-based neruodegeneration) and has taught over 750 doctoral and post-doctoral students. The book contains an essential distillation of the knowledge and material he had used to teach and lecture over many years.

Affiliations and Expertise

Unité de Biochimie, Université Catholique de Louvain, Louvain-la-Neuve, Belgium

Biological Inorganic Chemistry, 2nd Edition

Introduction and Principles
1. An overview of metals in biology
2. Basic coordination chemistry for biologists
3. Biological ligands for metal ions
4. Structural and molecular biology for chemists
5. An overview of intermediary metabolism and bioenergetics
6. Methods which can be used to study metals in biology
7. Metal assimilation pathways
8. Transport, storage and homeostasis of metal ions
Metals and key non-metals in biology
9. Sodium and potassium
10. Magnesium
11. Calcium
12. Zinc
13. Iron
14. Copper
15. Nickel and cobalt
16. Manganese
17. Molybdenum, vanadium, tungsten and chromium
18. Selected non-metals in biology
Metals in medicine, health and the environment
19. Biomineralisation
20. Metals in brain function
21. Metals and neurodegeneration
22. Metals in medicine and metals as drugs
23. Metals in the environment - Man-made environmental pollution

Quotes and reviews

"…a fine scholarly text written in a reader-friendly style to describe the various roles of metals in biological systems, human health, and the environment…The material of the second edition of this book has been updated, and new chapters have been included…I would highly recommend it to all interested biology, and biochemistry students and researchers."--Science Progress, February 18, 2014
"Crichton…offers this detailed and extensively illustrated text on inorganic components of biochemistry. Three introductory chapters explain the basic importance of metals in biology and orient biologists to coordination chemistry and chemists to molecular biology, respectively. General features of metal function are covered, including common ligands, their role in metabolism, assimilation and transport, and methods of study."--Reference & Research Book News, December 2013
"At first blush, inorganic biochemistry might sound like an oxymoron, but that is not the case here…Crichton’s book will be useful resource for students or researchers who want to understand the exciting world of inorganic biochemistry."--CHOICE, October 2012, Vol. 50, No. 02
"Robert Crichton has blended an element-centric approach to the subject with a biological thread that is engaging and helpful in exploring the topics in detail. The text is both accessible and detailed, but pitched at undergraduate level."--Chemistry World

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