Key Features
* Presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases
* Includes analysis of the role of the brain in the adaptive responses to disease
* Evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases
Readership
Neuroscientists, Immunologists, Pathologists, Pharmacologists, Internists, Veterinarians, Physiologists, Biologists
The Brain and Host Defense, 1st Edition
I. INTRODUCTION
1 - The hypothalamus is the central organ of immunoregulation; István Berczi, Barry Arnason;
II. DEVELOPMENT AND FUNCTION OF THE NEUROIMMUNE SYSTEM
2 - Leech Neuroimmune Signaling; Aurelie Tasiemski and Michel Salzet
3 - Morphogenesis of the Hypothalamus and Hypophysis; Kosuke Kawamura
4 - A Novel Genus of Specialized Anti-Inflammatory and Pro-Resolution Lipid Mediators; Gerard Bannenberg and Charles N. Serhan
5 - Neural and Non-Neural Stem Cells as Novel Therapeutic Modalities for Brain Injury; Ronen R. Leker and Éva Mezey
6 - The Role of the Toll-like Receptors in Neuropathology; Catherine E. Downes and Peter J. Crack
7 - Cytokines and the Immune-Neuroendocrine Network; Silvia G. Correa, Claudia E. Sotomayor and María Cecilia Rodríguez-Galán
8 - Orexin Containing Neurons and the Immune System; Natalia S. Novikova and Helen A. Korneva
9 - Central Pathways of Immunoregulation; Kathyrn M. Buller
10 - Brain Responses to Antigenic Challenges; Helen A. Korneva, Natalia S. Novikova
III. IMMUNOREGULATION BY THE NERVOUS SYsTEM
11 - Immunoregulation by the Nervous System: Role of the Endocrine System; Christopher John
12 - Conditioning of Immune Reactions; Laura Y. Gorczynski, Reginald M. Gorczynski
13 - Gender Issues in Host Defense; Matthias W. Wichmann and Martin K. Angele
IV. HOW THE BRAIN DEFENDS ITSELF
14 - Glial Cells in Brain Defense Mechanisms; Mami Noda
15 - Immunologic Privilege and the Brain; M. Kelly Nicholas and Rimas Lukas
16 - Immune Aspects of the Blood-Brain Barrier; Thomas E. Liggett and Roumen Balabanov
17 - Neuroprotective Activities of CD4+CD25+ Regulatory T Cells; Ashley D. Reynolds, David K. Stone, R. Lee Mosley, Howard E. Gendelman
V. THE ROLE OF THE BRAIN IN HOST DEFENSE IN DISEASE STATES
18 - Fever as a Host Defense Mechanism; Clark M. Blatteis
19 - Leukocytes as Mediator of Pain and Analgesia; Dagmar Hackel, Alexander Brack and Heike L. Rittner
20 - Tumor Necrosis Factor as Neuroinflammatory Mediator in Alzheimer’s Disease and Stroke. Molecular Mechanisms and Neuroinflammatory Imaging; Ulrich L.M. Eisel, Nikoletta Dobos, Rudi Dierckx, Paul Luiten and Jacob Korf
21 - Multiple Sclerosis and Depression – a Neuroimmunological Perspective; Barry G. Arnason
22 - Infection and Sepsis; Valentin A. Pavlov, Luis Ulloa, Christine N. Metz
23 - Restoration of Neuroimmune Disturbances in Rats by Extra High Frequency Electromagnetic Irradiation of the Skin; Elena G. Rybakina, Vernon J. Rogers, and Natalia S. Novikova
