Parkinson's Disease and Related Disorders, Part II

Parkinson's Disease and Related Disorders, Part II, 1st Edition

Parkinson's Disease and Related Disorders, Part II, 1st Edition,William Koller,Eldad Melamed,ISBN9780444528933





189 X 246

This volume is part of the Handbook of Clinical Neurology series, the world’s most comprehensive source of information in neurology. Now in its third generation, the series has an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology.

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Key Features

* A comprehensive resource on new advancements in the field of Parkinson’s research and related neurodegenerative diseases
* Important information on dramatic pharmacological advances in the management of Parkinson’s disease
* A platform to stimulate new research and better understanding of these common and disabling neurological disorders


This volume provides comprehensive information on Parkinson’s disease and related disorders, a group of diseases that are among the most common in the field of neurodegenerative study.

Through a high-level presentation of new research regarding these diseases, this handbook will give clinicians and neuroscientists alike a better understanding of the dramatic pharmacological advances made in the management of Parkinson’s disease, and the profound observations that have altered the medical community’s approach to other degenerative disorders of the nervous system.

Practitioners, researchers, and medical personnel will gain exciting insights into recent developments that form the basis for new therapeutic strategies and management protocols for the various neurological disorders that present with Parkinsonism.


Neurologists and research neuroscientists

William Koller


Affiliations and Expertise

Department of Neurology, UNC-Chapel Hill, NC, USA

Eldad Melamed


Affiliations and Expertise

Department of Neurology, Rabin Medical Center, Petaq Tiqva, Israel

Parkinson's Disease and Related Disorders, Part II, 1st Edition

Section 5: Treatment of Parkinson's disease
Physical therapy in Parkinson’s disease. Neuroprotection in Parkinson’s disease: clinical trials. Levodopa. Dopamine agonists. Monoamine oxidase A and B inhibitors in Parkinson’s disease. Anticholinergic medications. Antiglutamatergic drugs in the treatment of Parkinson’s disease. Investigational drugs. The importance of patients groups and collaboration
Section 6: Complications of therapy
Motor and non-motor fluctuations. Levodopa-induced dyskinesias in Parkinson’s disease. Treatment induced mental changes in Parkinson’s disease.
Section 7 Surgical treatment
Ablative surgery for the treatment of Parkinson’s disease. Deep brain stimulation. Transplantation. Gene therapy approaches for the treatment of Parkinson’s disease.
Section 8: Other parkinsonian disease syndromes
Multiple system atrophy. Progressive supranuclear palsy. Corticobasal degeneration. Infectious basis to the pathogenesis of Parkinson’s disease. Toxic causes of Parkinson’s disease. Drug induced parkinsonism. Vascular parkinsonism. Old age and Parkinson’s disease. Other degenerative processes. Hydrocephalus and structural lesions. Calcification of the basal ganglia. Trauma and Parkinson’s disease. Psychogenic parkinsonism. Parkinsonism and dystonia. Dementia with Lewy bodies. Myoclonus and parkinsonism.
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