Nuclear Receptors in Development

Nuclear Receptors in Development, 1st Edition

Nuclear Receptors in Development, 1st Edition,ISBN9780444528735

Elsevier Science




229 X 152

The latest research in the development of nuclear receptors

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Key Features

* Provides a compilation of reviews of several nuclear receptor subfamilies - such as TRs, PPARs, RARs, the orphan receptors COUP-TFs, RORs, and Ftz-F1 in embryonic and postnatal development.
* Offers a detailed section on retinoid receptor signaling
* Covers the role of co-repressors and co-activators in modulation of nuclear receptor functions


A superb compilation of reviews from leading experts in the field of nuclear receptors, volume 16 in the Advances in Developmental Biology series covers the role of different nuclear receptor subfamilies in development, physiology and metabolism. This volume brilliantly reviews how genetic defects in the function of nuclear receptors leads to various developmental defects. Receptors discussed include: thyroid receptors, peroxisome proliferators activated receptors, and retinoic acid receptors. Additionaly, this volume offers an indespesable chapter on the orphan receptors Ftz-F1, COUPs, and RORs in embryonic and postnatal development.


Developmental and cell biologists

Nuclear Receptors in Development, 1st Edition

1. Developmental Roles of the Thyroid Hormone Receptor ¦¡ And ¦¢ Genes
Lily Ng and Douglas Forrest

2. PPARs in fetal and early post-natal development
Nicolas Rotman, Liliane Michalik, B¨¦atrice Desvergne, Walter Wahli

3. Regulation of murine embryonic patterning and morphogenesis by retinoic acid signaling
Tracie Pennimpede, Don Cameron, and Martin Petkovich

4. Molecular mediators of retinoic acid signalling during development
Karen Niederreither and Pascal Doll¨¦

5. Hindbrain development and retinoids
Joel C. Glover, Jean-S¨¦bastien Renaud, Xavier Lampe, and Filippo M. Rijli

6. Retinoid receptors in vertebral patterning
Charlotte Rhodes and David Lohnes

7. Mouse Embryocarcinoma F9 cells and Retinoic Acid: A model to study the molecular mechanisms of endodermal differentiation
Ga¨¦tan Bour, Reshma Taneja and C¨¦cile Rochette-Egly

8. The Ftz-F1 family: orphan nuclear receptors regulated by novel protein-protein interactions
Leslie Pick, W. Ray Anderson, Jeffrey Shultz and Craig Woodard

9. Role of Chicken Ovalbumin Upstream Promoter-Transcription Factor I in
the Development of Nervous System
Ke Tang, Fu-Jung Lin, Sophia Y. Tsai and Ming-Jer Tsai

10. Retinoid-related Orphan Receptors (RORs): Roles in Cellular Differentiation and Development
Anton M. Jetten and Joung Hyuck Joo

11. Hairless, a nuclear receptor corepressor essential for skin function
Catherine C. Thompson and Gerard M. J. Beaudoin

12. Nuclear receptor transcriptional coactivators in development and metabolism
Janardan K. Reddy, Dongsheng Guo, Yuzhi Jia, Songtao Yu, and M. Sambasiva Rao
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