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Spinal Cord Injury

Spinal Cord Injury, 1st Edition

Handbook of Clinical Neurology Series

Spinal Cord Injury, 1st Edition,Joost Verhaagen,John McDonald,ISBN9780444521378

Verhaagen   &   McDonald   





262 X 192

A comprehensive and detailed overview of the latest science of spinal cord injury, diagnosis and treatment

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Key Features

*Comprehensive coverage of the latest scientific understanding of spinal cord injuries
*Detailed coverage of current treatment best practices and potential future treatments
*Connects leading edge research programs to future treatment opportunities 


Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury. Advances in neuroimaging, surgical treatment and application of electrical stimulation are dramatically impacting the treatment and outcome of these injuries. It provides a clear introduction to the core science of spinal cord injury, as well as to exciting research investigating new treatment options. Coverage includes brain-machine interfaces, transcranial stimulation, new pharmacological strategies, use of olfactory ensheathing cells, stem cells and precursor cells, gene therapy and molecular target discovery. This volume is a great resource for neuroscience and clinical neurology research specialists and practicing neurologists seeking a clear reference to the science and treatment of spinal cord injury.


Neuroscience and Clinical Neurology research specialists and practicing neurologists.

Joost Verhaagen

Affiliations and Expertise

Laboratory for Neuroregeneration, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

John McDonald

Affiliations and Expertise

Executive Vice President and Director, The International Center for Spinal Cord Injury, Baltimore, MD, USA

Spinal Cord Injury, 1st Edition

SECTION 1: Developmental and Anatomical Perspectives
1. Development and maturation of the spinal cord: implications of molecular and genetic defects
      G.W.J. Hawryluk, C.A. Ruff and M.G. Fehlings
2. Anatomy and biomechanics of the spinal column and cord
     V.J. Miele, M.M. Panjabi and E.C. Benzel
SECTION 2  Diagnosis and Prognosis
3. Clinical diagnosis and prognosis following spinal cord injury
     A.S. Burns, R.J. Marino, A.E. Flanders and H. Flett
4. Clinical neurophysiology in the prognosis and monitoring of traumatic spinal cord injury
    A.Curt and P.H. Ellaway
5. Concepts of aging with paralysis: implications for recovery and treatment
     M. Wirz and V. Dietz
6. Advanced MRI strategies for assessing spinal cord injury
     S.A. Smith, J.J. Pekar and P.C.M. van Zijl
SECTION 3  Acute spinal cord injury: medical, surgical and rehabilitative management
7. Advances in the management of spinal cord and spinal column injuries
     A. Taghva, D.J. Hoh and C.L. Lauryssen
8. Spinal cord injuries in children and adolescents
    L.C. Vogel, R.R. Betz and M.J. Mulcahey
9. The changing landscape of spinal cord injury
     N. Juknis, J.M. Cooper and O. Volshteyn
10. Surgical treatments to restore function control in spinal cord injury
       M.W. Keith and A. Peljovich
11. Advances in the rehabilitation management of acute spinal cord injury
      J.F. Ditunno, D.D. Cardenas, C. Formal and K. Dalal
12. Spasticity
       V. Dietz and T. Sinkjaer
13. Disordered cardiovascular control after spinal cord injury
       L.C. Weaver, J.C. Fleming, C.J. Mathias and A.V. Krassioukov
14. New concepts in the prevention of pressure sores
      K. Bogie, H.L. Powell and C.H. Ho
15. Functional electrical stimulation for bladder, bowel and sexual function
       G.H. Creasey and M.D. Craggs
16. Evidence based therapy for recovery of function after spinal cord injury
      S. Harkema, A. Behrman and H. Barbeau
17. Functional electrical stimulation: restoration of respiratory function
       R.P. Onders
18. Spinal cord stimulation: therapeutic benefits and movement generation after spinal cord
       C.H. Tator, K. Minassian and V.K. Mushahwar
19. Promoting optimal functioning in spinal cord injury: the role of rehabilitation
      S.T. Wegener, L.L. Adams and D. Rohe
SECTION 4  Chronic spinal cord injury - the changing perspective of neurorestorative rehabilitation, activity-based and surgical restoration therapies
20. The changing field of rehabilitation: optimizing spontaneous regeneration and functional
       J.W. McDonald III, C.L. Sadowsky and A. Stampas
21. The longitudinal spinal cord injury: lessons from intra spinal plexus, cauda equina and
       medullary conus lesions
       T. Carlstedt and L. Havtorn
22. Post-traumatic syringomyelia
      C.B. Shields, Y.P. Zhang and L.B.E. Shields
23. Post-traumatic deformity: prevention and management
      J. Wilson and J.M. Buchowski
SECTION 5  Preclinical research - bridging the gap between bench and bedside
24. Spinal cord injury clinical trials: translational process, review of past and proposed acute
      trials with reference to recommended trial guidelines
       J. Steeves and A. Blight
25. Translating preclinical approaches into human application
       V. Dietz and A. Curt
26. Translational spinal cord injury research: preclinical guidelines and challenges
       P.J. Reier, M.A. Lane, E.D. Hall, Y.D. Teng and D.R. Howland
27. Brain-machine interfaces and transcranial stimulation: future implications for directing
      functional movement and improving function after spinal injury in humans
      J.M. Carmena and L.G. Cohen
28. Approaches to repairing the damaged spinal cord: overview
       D. Becker and J.W. McDonald III
29. Limiting spinal cord injury by pharmacological intervention
      J.V. Priestley, A.T. Michael-Titus and W. Tetzlaff
30. Harmful and beneficial effects of inflammation after spinal cord injury: potential
      therapeutic implications
       S. David, R. López-Vales and V.W. Yong
31. Defeating inhibition of regeneration by scar and myelin components
       J.W. Fawcett, M.E. Schwab, L. Montani, N., Brazda and H.W. Müller
32. Realising the maximum potential of Schwann cells to promote recovery from spinal cord
       M.B. Bunge and P. McGhee Wood
33. Repair of CNS lesions by transplantation of olfactory ensheathing cells
      G. Raisman, S.C. Barnett and A. R amón-Cueto
34. Cell transplantation: stem cells and precursor cells
       Q. Cao and S.R. Whittemore
35. Gene therapy, neurotrophic factors and spinal cord regeneration
       A. Blesch, I. Fischer and M.H. Tuszynski
36. Scaffolds to promote spinal cord regeneration
       S. Sakiyama-Elbert, P.J. Johnson, S.I. Hodgetts, G.W. Plant and A.R. Harvey
37. Molecular target discovery for neural repair in the functional genomics era
       J. Verhaagen, R.E. van Kesteren, K.A.M. Bossers, H.D. MacGillavry, M.R. Mason and
      A.B. Smit
38. Combination therapies
       M. Oudega, E.J. Bradbury and M.S. Ramer

Quotes and reviews

"Providing the latest information on all aspects of spinal cord injury, this volume supplants a 1992 work published in the Handbook of Clinical Neurology series titled Spinal Cord Trauma. Bridging the gap between bench and bedside, coverage encompasses diagnosis and prognosis; medical, surgical, and rehabilitative management of acute spinal cord injury; therapies for chronic spinal cord injury; and preclinical research."--Reference & Research Book News, October 2013

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