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Systems Biology
 
 

Systems Biology, 1st Edition

Philosophical Foundations

 
Systems Biology, 1st Edition,Fred Boogerd,Frank Bruggeman,Jan-Hendrik Hofmeyr,H.V. Westerhoff,ISBN9780444520852
 
 
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Boogerd   &   Bruggeman   &   Hofmeyr   &   Westerhoff   

Elsevier Science

9780444520852

9780080475271

360

240 X 165

Systems Biology, a new philosophy?

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Key Features

* Answers the question of what distinguishes the living from the non-living
* An in-depth look to a vigorous and expanding discipline, from molecule to system
* Explores the region between individual components and the system

Description

Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from philosophy to chemistry. Studying the philosophical foundations of systems biology may resolve a longer standing issue, i.e., the extent to which Biology is entitled to its own scientific foundations rather than being dominated by existing philosophies.

Readership

Computational biologists, Molecular biologists, Cellular biologists, Systems biologists, Bioinformaticians, Philosophers of Science, Philosophers of Biology

Fred Boogerd

Affiliations and Expertise

Vrije Universiteit, Faculty of Earth and Life Sciences, Dept. of Molecular Cell Physiology, Amsterdam, The Netherlands

Frank Bruggeman

Affiliations and Expertise

Vrije Universiteit, Faculty of Earth and Life Sciences, Department of Molecular Cell Physiology, Amsterdam, The Netherlands

Jan-Hendrik Hofmeyr

Affiliations and Expertise

University of Stellenbosch, Faculty of Science, Department of Biochemistry, Matieland, South Africa

H.V. Westerhoff

Affiliations and Expertise

Vrije Universiteit, Faculty of Earth and Life Sciences, Dept. of Molecular Cell Physiology, Amsterdam, The Netherlands

Systems Biology, 1st Edition

Introduction
1. Towards philosophical foundations of Systems Biology: Introduction

Research programs of Systems Biology
2. The methodologies of Systems Biology
3. Methodology is Philosophy
4. How can we understand metabolism?
5. On Building Reliable Pictures with Unreliable Data: an Evolutionary and Developmental Coda for the New Systems Biology?


Theory / models
6. Mechanism and mechanical explanation in cell biology
7. Theories, Models, and Equations in Systems Biology
8. All models are wrong.......some more than others
9. Data without models merging with models without data

Organization in biological systems
10. The biochemical factory that autonomously fabricates itself: a systems-biological view of the living cell
11. A systemic approach to the origin of biological organization
12. Organization and biological mechanisms: organized to maintain autonomy
13. The disappearance of function from 'self-organizing systems'

Conclusion
14. Afterthoughts as foundations for Systems Biology
 
 
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