Hyperkinetic Movement Disorders

Hyperkinetic Movement Disorders, 1st Edition

Hyperkinetic Movement Disorders, 1st Edition,William Weiner,Eduardo Tolosa,ISBN9780444520142

Weiner   &   Tolosa   





262 X 192

This volume is part of the Handbook of Clinical Neurology series, the world’s most comprehensive source of information in neurology. Now in its third generation, the series has an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology.

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Key Features

* An authoritative, comprehensive guide to movement disorders
* An invaluable reference for the diagnosis and treatment of hyperkinetic diseases and syndromes
* High-level discussions that are ideal for specialists in movement disorders, practitioners and residents alike



The Handbook of Clinical Neurology Vol 100: Hyperkinetic Movement Disorders discusses hyperkinetic disorders related mainly to basal ganglia dysfunction and pathology. It contains 13 sections and 51 chapters written by authoritative and experienced investigators and clinicians in this extremely broad and diverse group of diseases and syndromes. The first section on choreoathetoid diseases and syndromes includes chapters on Huntington’s disease and Huntington’s disease look-alikes; spinocerebellar degenerations; neuroacanthocytosis; entatorubral-pallidoluysian atrophy; neuroferritinopathy; neurodegeneration with brain iron accumulation; mitochondrial disorders; acquired hepatocerebral degeneration; benign hereditary chorea; and “senile chorea.” The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. These include immune-related chorea, vascular chorea, metabolic disturbances that can induce chorea, chorea in other medical settings (e.g., postpump chorea in children, cancer-related paraneoplastic syndromes), myoclonus, essential tremor, and dystonia, including dystonia plus syndromes. There are also chapters on tardive dyskinesia, unusual clinical syndromes, and tics and stereotyped movements in children. The text is a valuable resource for neurology and psychiatry residents, practicing neurologists and psychiatrists, and specialists in movement disorders.


Neuroscience research workers

William Weiner


Affiliations and Expertise

Professor and Chairman, Department of Neurology, University of Maryland School of Medicine; Director, Maryland Parkinson's Diseases and Movement Disorders Centre, Baltimore, MD, USA

Eduardo Tolosa


Affiliations and Expertise

Chief of Neurology Service, Hospital Clinic, University of Barcelona, Spain

Hyperkinetic Movement Disorders, 1st Edition





Section 1 Choreoathetoid diseases and syndromes

1. Huntington’s disease - clinical signs, symptoms, presymptomatic diagnosis, and diagnosis

2. Huntington’s disease

3. Molecular biology of Huntington’s disease

4. Huntington’s disease - neuropathology

5. Huntington’s disease look-alikes

6. Spinocerebellar degenerations

7. Neuroacanthocytosis

8. Dentatorubral pallidoluysian atrophy

9. Neurodegeneration with brain iron accumulation

10. Movement disorders and mitochondrial disease

11. Acquired hepatocerebral degeneration

12. Benign hereditary chorea

13. Senile chorea

Section 2 Immune-related chorea

14. Sydenham’s chorea

15. Chorea gravidarum

16. Antiphospholipid syndrome and other lupus-related movement disorders

Section 3 Vascular-related chorea

17. Hemiballismus

18. Vascular chorea in adults and children

19. Polycythemia and chorea

Section 4 Metabolic disturbances

20. Hyperthyroid chorea

21. Hyperglycemic nonketotic states and other metabolic imbalances

Section 5 Chorea in other medical settings

22. Postoperative encephalopathy with choreoathetosis

23. Movement disorders in patients with multiple sclerosis

24. Paraneoplastic syndromes causing movement disorders

25. Hyperkinetic movement disorders associated with HIV and other viral infections

26. Chorea caused by toxins

27. Drug-induced hyperkinetic movement disorders by nonneuroleptic agents

Section 6 Other syndromes

28. Paroxysmal choreodystonic disorders

29. Painful legs and moving toes

Section 7 Athetosis

30. Birth-related syndromes of athetosis and kernicterus

Section 8 Myoclonus

31. Myoclonus

32. Startle syndromes

Section 9 Essential tremor

33. Essential tremor

34. Management of essential tremor, including medical and surgical approaches

35. Orthostatic tremor - a review

Section 10 Dystonia

36. Early-onset primary dystonia

37. Adult-onset dystonia

38. Nonprimary dystonias

39. Dopa-responsive dystonia

40. Rapid-onset dystonia-parkinsonism

41. Myoclonus-dystonia syndrome

Section 11 Tardive dyskinesia

42. Typical and atypical neuroleptics

43. Epidemiology of tardive dyskinesia before and during the era of modern antipsychotic drugs

44. Unusual focal dyskinesias

Section 12 Tics

45. Stereotypic movement disorders

46. Tourette syndrome and other tic disorders

Section 13 Other syndromes

47. Restless legs syndrome

48. Hemifacial spasm

49. Wilson’s disease

50. Task-specific tremor

51. Hyperkinetic psychogenic movement disorders


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