Hyperkinetic Movement Disorders

Hyperkinetic Movement Disorders, 1st Edition

Handbook of Clinical Neurology Vol. 100 (Series Editors: Aminoff, Boller and Swaab)

Hyperkinetic Movement Disorders, 1st Edition,William Weiner,Eduardo Tolosa,ISBN9780444520142

Weiner   &   Tolosa   





262 X 192

This volume is part of the Handbook of Clinical Neurology series, the world’s most comprehensive source of information in neurology. Now in its third generation, the series has an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology.

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Key Features

* An authoritative, comprehensive guide to movement disorders
* An invaluable reference for the diagnosis and treatment of hyperkinetic diseases and syndromes
* High-level discussions that are ideal for specialists in movement disorders, practitioners and residents alike



The Handbook of Clinical Neurology Vol 100: Hyperkinetic Movement Disorders discusses hyperkinetic disorders related mainly to basal ganglia dysfunction and pathology. It contains 13 sections and 51 chapters written by authoritative and experienced investigators and clinicians in this extremely broad and diverse group of diseases and syndromes. The first section on choreoathetoid diseases and syndromes includes chapters on Huntington’s disease and Huntington’s disease look-alikes; spinocerebellar degenerations; neuroacanthocytosis; entatorubral-pallidoluysian atrophy; neuroferritinopathy; neurodegeneration with brain iron accumulation; mitochondrial disorders; acquired hepatocerebral degeneration; benign hereditary chorea; and “senile chorea.” The remaining chapters focus on the abnormal involuntary movements associated with each disease or syndrome. These include immune-related chorea, vascular chorea, metabolic disturbances that can induce chorea, chorea in other medical settings (e.g., postpump chorea in children, cancer-related paraneoplastic syndromes), myoclonus, essential tremor, and dystonia, including dystonia plus syndromes. There are also chapters on tardive dyskinesia, unusual clinical syndromes, and tics and stereotyped movements in children. The text is a valuable resource for neurology and psychiatry residents, practicing neurologists and psychiatrists, and specialists in movement disorders.


Neuroscience research workers

William Weiner


Affiliations and Expertise

Professor and Chairman, Department of Neurology, University of Maryland School of Medicine; Director, Maryland Parkinson's Diseases and Movement Disorders Centre, Baltimore, MD, USA

Eduardo Tolosa


Affiliations and Expertise

Chief of Neurology Service, Hospital Clinic, University of Barcelona, Spain

Hyperkinetic Movement Disorders, 1st Edition

Foreword Preface Dedication Contributors Section 1 Choreoathetoid diseases and syndromes 1. Huntington’s disease - clinical signs, symptoms, presymptomatic diagnosis, and diagnosis 2. Huntington’s disease 3. Molecular biology of Huntington’s disease 4. Huntington’s disease - neuropathology 5. Huntington’s disease look-alikes 6. Spinocerebellar degenerations 7. Neuroacanthocytosis 8. Dentatorubral pallidoluysian atrophy 9. Neurodegeneration with brain iron accumulation 10. Movement disorders and mitochondrial disease 11. Acquired hepatocerebral degeneration 12. Benign hereditary chorea 13. Senile chorea Section 2 Immune-related chorea 14. Sydenham’s chorea 15. Chorea gravidarum 16. Antiphospholipid syndrome and other lupus-related movement disorders Section 3 Vascular-related chorea 17. Hemiballismus 18. Vascular chorea in adults and children 19. Polycythemia and chorea Section 4 Metabolic disturbances 20. Hyperthyroid chorea 21. Hyperglycemic nonketotic states and other metabolic imbalances Section 5 Chorea in other medical settings 22. Postoperative encephalopathy with choreoathetosis 23. Movement disorders in patients with multiple sclerosis 24. Paraneoplastic syndromes causing movement disorders 25. Hyperkinetic movement disorders associated with HIV and other viral infections 26. Chorea caused by toxins 27. Drug-induced hyperkinetic movement disorders by nonneuroleptic agents Section 6 Other syndromes 28. Paroxysmal choreodystonic disorders 29. Painful legs and moving toes Section 7 Athetosis 30. Birth-related syndromes of athetosis and kernicterus Section 8 Myoclonus 31. Myoclonus 32. Startle syndromes Section 9 Essential tremor 33. Essential tremor 34. Management of essential tremor, including medical and surgical approaches 35. Orthostatic tremor - a review Section 10 Dystonia 36. Early-onset primary dystonia 37. Adult-onset dystonia 38. Nonprimary dystonias 39. Dopa-responsive dystonia 40. Rapid-onset dystonia-parkinsonism 41. Myoclonus-dystonia syndrome Section 11 Tardive dyskinesia 42. Typical and atypical neuroleptics 43. Epidemiology of tardive dyskinesia before and during the era of modern antipsychotic drugs 44. Unusual focal dyskinesias Section 12 Tics 45. Stereotypic movement disorders 46. Tourette syndrome and other tic disorders Section 13 Other syndromes 47. Restless legs syndrome 48. Hemifacial spasm 49. Wilson’s disease 50. Task-specific tremor 51. Hyperkinetic psychogenic movement disorders Index

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