Lead Molecules from Natural Products

Lead Molecules from Natural Products, 1st Edition

Discovery and New Trends

Lead Molecules from Natural Products, 1st Edition,Mahmud Tareq Hassan Khan,Arjumand Ather,ISBN9780444516190

Khan   &   Ather   

Elsevier Science




240 X 165

Reveals the latest research on the use of medicinal plants

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Key Features

* Explains the effects of plant extracts on gene expression profiling.

* Details medicinal plant research from around the world

* Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.


Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research.

This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered.

The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations.


Phytochemists; Combinatorial Chemists; Pharmacologists; Scientists engaged in Drug discovery and development; Industrial research groups developing drugs from plants; Departments of pharmaceutics; Institutes for Drug Research; Pharmaceutical companies; Manufacturers of herbal and ayurvedic medicines and cosmetic products
Manufacturers of natural products

Mahmud Tareq Hassan Khan

Affiliations and Expertise

International Center for Chemical Sciences, University of Karachi, Pakistan

Arjumand Ather

Affiliations and Expertise

The Norwegian Structural Biology Centre, University of Tromso, Norway

Lead Molecules from Natural Products, 1st Edition

Reverse Pharmacognosy: a new concept for accelerating natural drug discovery
Quoc-Tuan DO and Philippe BERNARD

Effects of Plant Extracts on Gene Expression Profiling: from Macrorrays to Microarray Technology
Carlo Mischiati, Alessia Sereni, Mahmud Tareq Hassan Khan, Ilaria Lampronti and Roberto Gambari

Effects of Medicinal Plant Extracts on Molecular Interactions between DNA and Transcription Factors
Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Giordana Feriotto1, Carlo Mischiati, Monica Borgatti and Roberto Gambari

Plants with Antitumor Properties: from Biologically Active Molecules to Drugs
Ilaria Lampronti, Mahmud Tareq Hassan Khan, Nicoletta Bianchi, Elisabetta Lambertini, Roberta Piva, Monica Borgatti and Roberto Gambari

Herbal Extracts and Compounds Active against Herpes Simplex Virus
Kenneth D. Thompson

Cough and its Pharmacological Modulation
Nosalova, G., Mokry, J., Franova, S

Phytotherapy of the Cough
Franova, S., Nosalova G., Mokry, J.

The Medicinal Potential of Black seed (Nigella sativa) and its Components
Hala Gali-Muhtasib, Regine Schneider-Stock

Cyclin Dependent Kinase Inhibitors from Natural Sources: Recent Advances and Future Prospects for Cancer Treatment
Hala Gali-Muhtasib

Anticancer and Medicinal Properties of Essential Oil and Extracts of East Mediterranean Sage (Salvia triloba)
Hala Gali-Muhtasib

Marine Organisms from Brazil as Source of Potential Anticancer Agents
Letícia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete A. Moraes, Adaíla Marta Paixão Almeida, Manoel Odorico de Moraes, Tito Monteiro da Cruz Lotufo

Anticancer Potential of Northeast Brazilian Plants
Cláudia Pessoa, Letícia Veras Costa-Lotufo, Albert Leyva, Maria Elisabete Amaral de Moraes, Manoel Odorico Moraes

Safety and Efficacy of Phytomedicines
Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Letícia Veras Costa-Lotufo, Cláudia Pessoa, Maria Elisabete Amaral de Moraes

Pharmacological and Biochemical Profiling of Lead Compounds from Traditional Remedies: the case of Croton cajucara
Maria Aparecida M. Maciel, Tereza Neuma C. Dantas, Angelo C. Pinto, Valdir F. Veiga Jr., Carlos R. Kaiser, Nuno A. Pereira, Cristina M. T. S. Carneiro, Frederico A. Vanderlinde, Antônio J. Lapa, Aniele R. Agner, Ilce M. S. Cólus, Juliana Echevarria-Lima, Noema F. Grynberg, Andressa Esteves-Souza, Kenia Pissinate, Aurea Echevarria

Antihypertensive Peptides from Natural Resources
Toshiro Matsui, Kiyoshi Matsumoto

Xanthones As Therapeutic Agents: Chemistry And Pharmacology
Noungoue Tchamo Diderot, Ngouela Silvere, and Tsamo Etienne

Inhibition of immunodeficiency type-1 virus (HIV-1) life cycle by medicinal plants extracts and plant-derived compounds
Roberto Gambari

Anticancer Properties of Saffron, Crocus sativus Linn.
José-Antonio Fernández

Lead Compounds and Drug Candýdates from Some Turkýsh Plants for Human Health
Ýlkay Orhan, Bilge Þener

Molecular Design of Multifunctional Anti-Salmonella Agents
Based on Natural Products
Isao Kubo, Ken-ichi Fujita, Ken-ichi Nihei and Aya Kubo

Plant Growth Inhibitory Activities by Secondary Metabolites Isolated from Latin American Flora
Carlos L. Céspedes, Juan C. Marín, Mariana Domínguez, J. Guillermo Avila, Blanca Serrato.

Metabolomics – Systematic Studies of the Metabolic Profiling
Mahmud Tareq Hassan Khan, Arjumand Ather
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