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Advances in Immunology
1st Edition, Volume 127 - June 9, 2015
Editor: Frederick W. Alt
Language: English
Hardback ISBN:9780128022450
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eBook ISBN:9780128024331
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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wi…Read more
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Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.
Contributions from leading authorities
Informs and updates on all the latest developments in the field
Immunologists and infectious disease specialists, cell biologists and hematologists.
Cross-Presentation in Mouse and Human Dendritic CellsElodie Segura and Sebastian Amigorena
HLA-G: An Immune Checkpoint MoleculeEdgardo D. Carosella, Nathalie Rouas-Freiss, Diana Tronik-Le Roux, Philippe Moreau and Joel LeMaout
Activation and Function of iNKT and MAIT CellsShilpi Chandra and Mitchell Kronenberg
IgE and Mast Cells: the Endogenous AdjuvantHans C. Oettgen and Oliver T. Burton
RNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeEvangelos Pefanis and Uttiya Basu
No. of pages: 332
Language: English
Edition: 1
Volume: 127
Published: June 9, 2015
Imprint: Academic Press
Hardback ISBN: 9780128022450
eBook ISBN: 9780128024331
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Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA