Save up to 30% on Elsevier print and eBooks with free shipping. No promo code needed.
Save up to 30% on print and eBooks.
Principles of Animal Research for Graduate and Undergraduate Students
1st Edition - November 16, 2016
Authors: Mark A. Suckow, Kay Stewart
Language: English
Paperback ISBN:9780128021514
9 7 8 - 0 - 1 2 - 8 0 2 1 5 1 - 4
eBook ISBN:9780128023662
9 7 8 - 0 - 1 2 - 8 0 2 3 6 6 - 2
Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all a…Read more
Purchase options
LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education.
Provides background material for students to understand the broader backdrop against which animal research is undertaken
Includes ethical and regulatory information
Covers commonly used animal models and the process to choose a model for biomedical research
Early researchers, undergraduate and graduate students, researchers and professors studying laboratory animal research; technicians in laboratory animal science; pre-veterinarians and veterinarians; and students/early researchers working with laboratory animals across biological and biomedical research
Preface
Chapter 1. Brief Historical Overview on the Use of Animals in Research
1.1. Introduction
1.2. Early Attitudes Toward Animal Health and Disease
1.3. Development and Emergence of New Animal Models
1.4. Improvements in Approaches to Animal Care
1.5. Summary
Chapter 2. Philosophical and Ethical Foundations
2.1. Basic Approaches
2.2. Animal Welfare Versus Animal Rights
2.3. Opposition to and Benefits of Animal Experimentation
2.4. Professional Ethics Relating to Biomedical Research
Chapter 3. Regulations and Guidelines
3.1. Introduction
3.2. US Animal Welfare Act
3.3. Public Health Service Policy
3.4. FDA Good Laboratory Practices
3.5. Other Laws, Regulations, and Policies
3.6. Fish and Wildlife Service and NIH Positions on Chimpanzees
3.7. Professional and Scientific Associations
3.8. International Laws and Regulations
3.9. Conclusions
Chapter 4. Institutional Animal Care and Use Committee
4.1. Purpose and Function
4.2. Committee Composition
4.3. IACUC Review of Proposed Activities and Projects
4.4. Periodic Review of the Animal Care and Use Program and Facilities
4.5. Investigation of Concerns Regarding the Use and Treatment of Vertebrate Animals
4.6. Sample Size Estimation in Laboratory Animal Experiments
Chapter 5. Experimental Variables
5.1. The Research Environment
5.2. Environmental Enrichment
5.3. Animal Health Monitoring Program
5.4. Summary
Chapter 6. Model Selection
6.1. Selection Criteria
6.2. Types of Models
6.3. Spontaneous Mutation Models
6.4. Random Mutation Models
6.5. Genetically Manipulated Models
6.6. Chemically Induced Models
6.7. Physically Induced Models
6.8. Surgical Models
6.9. Behavioral Models
6.10. Production Models
Chapter 7. Commonly Used Animal Models
7.1. The Mouse
7.2. The Rat
7.3. The Rabbit
7.4. Zebrafish
7.5. Amphibians and Reptiles
7.6. Birds
7.7. Other Small Mammals
7.8. Summary
Chapter 8. Common Technical Procedures in Rodents
8.1. Handling and Restraint Methods
8.2. Identification
8.3. Common Technical Procedures
8.4. Rodent Anesthesia
8.5. Rodent Surgery
8.6. Euthanasia
8.7. Necropsy
8.8. Summary
Chapter 9. Considerations for Use of Vertebrates in Field Studies
9.1. Reasons for Conducting Field Research
9.2. Sources for Specific Technique Information
9.3. Initial Steps for Undertaking Field Research Involving Vertebrates
9.4. Observational Techniques
9.5. Capturing Animals
9.6. Handling Animals
9.7. Identification and Marking of Animals
9.8. Conclusion
Chapter 10. Personnel Safety in the Care and Use of Laboratory Animals
10.1. Introduction
10.2. Occupational Health and Safety Programs
10.3. Hazards Associated With Animal Research
10.4. Best Practices for Prevention
10.5. Conclusions: Personnel Engagement and Awareness
Chapter 11. Thesis Development
11.1. Preparation
11.2. Thesis Sections
11.3. Finalizing the Thesis
11.4. Conclusion
Glossary of Terms and Acronyms
Index
No. of pages: 286
Language: English
Edition: 1
Published: November 16, 2016
Imprint: Academic Press
Paperback ISBN: 9780128021514
eBook ISBN: 9780128023662
MS
Mark A. Suckow
Mark Suckow received his DVM from the University of Wisconsin in 1987 and subsequently completed a post-doctoral residency in laboratory animal medicine at the University of Michigan in 1990. He spent 8 years as a clinical laboratory animal veterinarian at Purdue University and then 17 years at the University of Notre Dame where he served as Director of the Freimann Life Science Center and later as Associate Vice President for Research Compliance. Prior to coming to the University of Kentucky, he was Professor of Veterinary Population Medicine and Director, Research Animal Resources at the University of Minnesota. With an interest in cancer models, biomaterials models, and vaccines, Dr. Suckow has functioned as an independent and collaborative investigator and has published in refereed journals and has seven issued patents related to vaccine adjuvants and cancer vaccines. He has written or edited over 20 books on topics related to research and laboratory animal medicine. Further, he served as the 2006 President of the American Association for Laboratory Animal Science and the 2011 President of the American Society of Laboratory Animal Practitioners; and currently he serves on the AVMA Council on Research and is a member of the Council on Accreditation of AAALAC, International.
Affiliations and expertise
Associate Vice President for Research, Attending Veterinarian, University of Kentucky, USA.
KS
Kay Stewart
Kay Stewart is the Associate Director of the Freimann Life Science Centre at the University of Notre Dame. Her research straddles both the role of animals in biomedical research and the ethics and treatment of animals in academic settings.
Affiliations and expertise
Associate Director of Freimann Life Science Center, University of Notre Dame, Notre Dame, IN, USA
Read Principles of Animal Research for Graduate and Undergraduate Students on ScienceDirect