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Advances in Clinical Chemistry
1st Edition, Volume 65 - May 20, 2014
Editor: Gregory S. Makowski
Language: English
Hardback ISBN:9780128001417
9 7 8 - 0 - 1 2 - 8 0 0 1 4 1 - 7
eBook ISBN:9780128003039
9 7 8 - 0 - 1 2 - 8 0 0 3 0 3 - 9
Volume 65 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scien…Read more
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Volume 65 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.
Expertise of international contributors
Latest cutting-edge technologies
Comprehensive in scope
Clinical Laboratory Professionals, Physicians and Research Scientists
Preface
Chapter One: HDL Metabolism and Atheroprotection: Predictive Value of Lipid Transfers
Abstract
1 Introduction
2 HDL Composition
3 HDL Subclasses
4 HDL Metabolism and Reverse Cholesterol Transport
5 Other HDL Functions
6 Proatherogenic HDL
7 Cholesterol Ester Transfer Protein
8 Phospholipid Transfer Protein
9 CETP and PLTP in CVD
10 Simultaneous Transfer of Lipids to HDL
11 Conclusion
Acknowledgments
Chapter Two: Diagnosis of Infection in Critical Care
Abstract
1 Background
2 Immunologic Basis of Sepsis
3 New Tools for Bacterial Identification
4 Useful Markers of Infectious Complications According to the Affected Organ and Patient Status
5 Conclusions
Chapter Three: Metabolomics in Nephrotoxicity
Abstract
1 Introduction
2 Nephrotoxicity or Renal Toxicity
3 Metabolomics in Biomarker Discovery
4 Metabolomics Application in Animal Model-Based Nephrotoxicity
5 Metabolomics in Clinical Nephrotoxicity
6 Conclusion and Future Perspectives
Acknowledgments
Chapter Four: Metabolic Syndrome in Pediatrics
Abstract
1 Introduction
2 Clinical Features of Children with Metabolic Syndrome
3 Metabolic Characteristics of Children and Adolescents with Metabolic Syndrome
4 Prediabetes and Type 2 Diabetes in Youth
5 Nonalcoholic Fatty Liver Disease in Youth
6 Association Between “Lipid partitioning” and Metabolic Syndrome
7 Is There a Healthy Metabolic Phenotype in Obesity?
8 Role of Subcutaneous Fat in the Pathogenesis of Metabolic Syndrome
9 Novel Biomarkers of Metabolic Syndrome
10 Adipocyte Lipid-Droplet Molecules
11 Inflammation Markers
Acknowledgments
Chapter Five: CSF in Alzheimer's Disease
Abstract
1 Introduction
2 AD—Genetics and Pathophysiology
3 CSF in AD
4 Candidate AD Biomarkers and Markers of Other Pathologies
5 Standardization Efforts
6 Concluding Remarks
Acknowledgments
Chapter Six: Food Allergy Testing
Abstract
1 Food Allergy—A Growing Problem
2 Testing for Food Allergy
3 Conclusions
Chapter Seven: Matrix Metalloproteinases in Biologic Samples
Abstract
1 Regulation of MMPs
2 Detection of MMPs in Biological Samples, Total Zymogen Versus Enzymatic Activity
3 Confounders of MMP Measurements
Index
No. of pages: 240
Language: English
Edition: 1
Volume: 65
Published: May 20, 2014
Imprint: Academic Press
Hardback ISBN: 9780128001417
eBook ISBN: 9780128003039
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in his joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President and Chief Scientific Officer for Clinical Laboratory Partners in Newington CT, USA.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USA
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