Paul Ehrlich's Receptor Immunology

Paul Ehrlich's Receptor Immunology, 1st Edition

The Magnificent Obsession

Paul Ehrlich's Receptor Immunology, 1st Edition,Arthur Silverstein,ISBN9780126437652


Academic Press




229 X 152

A comprehensive and fascinating history of one of the founding fathers of immunology

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Key Features

the selectionist theory of antibody formation
kinetics of primary and secondary antibody response
quantitative methods of measurement of antigens and antibody
demonstration of passive transfer of immunity from mother to foetus


This book describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field.


Immunologists, virologists, geneticists, molecular biologists, hematologists, and science historians.

Arthur Silverstein

Affiliations and Expertise

The Johns Hopkins University School of Medicine, Baltimore, MD, USA

View additional works by Arthur M. Silverstein

Paul Ehrlich's Receptor Immunology, 1st Edition

List of Plates.
Introduction by Sir Gustav Nossal.
The Background to Ehrlich's Immunology: Origins of the Receptor Theory.
On Ricin and Abrin: Quantitation Enters Immunity Research.
The Value of Mother's Milk: The Founding of Pediatric Immunology.
The Standardization of Toxins and Antitoxins.
The Toxin-Antitoxin Reaction: Theory Outpaces Data.
The Side-Chain Theory of Antibody Formation.
Immune Hemolysis: Bordet Challenges Ehrlich.
New Scientific Challenges.
Ehrlich's Scientific Style.
Appendix A. Paul Ehrlich's Honors.
Appendix B. Paul Ehrlich's Scientific Bibliography.
Name Index.
Subject Index.

Quotes and reviews

"...it gives a rich and detailed overview of the intellectual development of Ehrlich's immunology"-MEDICAL HISTORY (April 2003)
@qu:"It is a sophisticated, closely argued, and clearly written analysis of Ehrlich's contributions to immunology. The adroit use of a wealth of original sources enriches and strengthens the text."
@source:--Robert S. Schwartz M.D. in NEW ENGLAND JOURNAL OF MEDICINE (March 2002)
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