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Key Chiral Auxiliary Applications
 
 

Key Chiral Auxiliary Applications, 2nd Edition

 
Key Chiral Auxiliary Applications, 2nd Edition,Gregory Roos,ISBN9780124170346
 
 
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Academic Press

9780124170346

1270

276 X 216

This compilation allows the reader to make carefully informed selections of an auxiliary for a specific asymmetric synthetic transformation without spending hours searching many resources.

Print Book

Hardcover

In Stock

Estimated Delivery Time
USD 206.25
USD 275.00
 
 

Key Features

  • Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds
  • Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource

Description

Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data.  Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation.

Readership

Industrial, organic, and pharmaceutical chemists in industry and academia.

Gregory Roos

Greg Roos obtained his formal education, comprising of a BSc (1971), BSc Honours (1972), and PhD in Organic Synthesis (1976), at the University of Cape Town. A postdoctoral fellowship (1978) with Richard Cookson at the University of Southampton was followed by a few years of pharmaceutical industrial experience. His full-time academic career began at the University of Natal, Pietermaritzburg (1981-1994), and continued at Murdoch University, Perth, Australia (1994-1997). This was followed by an extended period in the Middle East, including Sultan Qaboos University, Oman (1998-2004) and The Petroleum Institute, Abu Dhabi (2004-2008). He has successfully taught across various cultures and has received awards for his teaching contributions and innovations. Currently, as an adjunct Professor at Murdoch University (since 2009), he now shares his time between Perth and Dubai. His research interests have focused on the development of synthetic methodology, with particular interest in asymmetric processes. This led to numerous publications and conference contributions in the areas of the Baylis-Hillman reaction, imidazolidinone chiral auxiliaries, and dirhodium catalyst development and applications. This period also included a number of collaborative research visits with Tony McKervey (University College Cork & Queen’s University, Belfast), C. K. Sha (Shin Hua University, Taiwan), Mike Doyle (Trinity University, San Antonio), and Ron Warrener (CQU Rockhampton, Queensland). In 2001, he received the Merck Gold Medal for research from the South African Chemical Institute.

Affiliations and Expertise

Murdoch University, Perth, Western Australia

Key Chiral Auxiliary Applications, 2nd Edition

Chapter 1 - Introduction
Section A - SUBSTITUTION RELATED PROCESSES
Chapter 2 - Alkylation and Related Reactions I
Chapter 3 - Alkylation and Related Reactions II
Chapter 4 - Alkylation and Related Reactions III
Chapter 5 - Alkylation and Related Reactions IV
Section B - ADDITION TO UNSATURATED SYSTEMS
Chapter 6 - Electrophilic Related Addition To C=C
Chapter 7 - Conjugate Addition I
Chapter 8 - Conjugate Addition II
Chapter 9 - Conjugate Addition III
Chapter 10 - Addition To C=N Bonds
Chapter 11 - Addition To C=O Bonds I
Chapter 12 - Addition To C=O Bonds II
Chapter 13 - Addition To C=O Bonds III
Section C - PERICYCLIC AND RELATED REACTIONS
Chapter 14 - Cycloadditions I
Chapter 15 - Cycloadditions II
Chapter 16 - Rearrangements
Section D - MISCELLANEOUS PROCESSES
Chapter 17a - Kinetic Resolution-Related React
Chapter 17b - Miscellaneous Reactions

 
 
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