@bul:* Provides state-of-the-art information on a field with broad implications to many areas of biology
* Includes detailed coverage of the structure and regulation of all major matrix metalloproteinases
* Chapters focus on a timely and expanding field
* Topics have direct relevance to understanding human disease pathology of cancer, arthritis, and vascular disease
* Discusses latest strategies used in the development of new therapeutics to inhibit metalloproteinase activity
The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity. This work will be an indispensable reference tool for investigators with an interest in extracellular matrix biology, matrix turnover, enzymology and biochemistry of proteinases, developmental biology, pathology, and therapeutic interventions.
Graduate students and researchers in cell biology, cancer biology, molecular biology, biochemistry departments. Scientists and physicians with an interest in the pathogenesis of cancer, arthritis, wound healing, and vascular disease. Researchers and product design scientists in the pharmaceutical and biotechnology industries.
Matrix Metalloproteinases, 1st Edition
The Matrix Metalloproteinase Family, J.F. Woessner, Jr.
Interstitial Collagenases, J.J. Jeffrey
Stromelysins 1 and 2, H. Nagase
72-kDa Gelatinase (Gelatinase A): Structure, Activation, Regulation, and Substrate Specificity, A.E. Yu, A.N. Murphy and W.G. Stetler-Stevenson
Gelatinase B: Structure, Regulation, and Function, T.H. Vu and Z. Werb
Matrilysin, C.L. Wilson and L.M. Matrisian
Macrophage Elastase (MMP-12), S.D. Shapiro and R.M. Senior
Membrane-Type Matrix Metalloproteinases and Cell Surface-Associated Activation Cascades for Matrix Metalloproteinases, V. Knauper and G. Murphy
Substrate Specificity and Mechanism of Substrate Recognition of the Matrix Metalloproteinases, V. Imper and H.E. Van Wart
Synthetic Inhibitors of Matrix Metalloproteinases, P.D. Brown
Matrix Metalloproteinases in Tissue Repair, W.C. Parks, B.D. Sudbeck, G.R. Doyle and U.K. Saariahlo-Kere
Regulation of Matrix Metalloproteinase Gene Expression, M.E. Fini, J.R. Cook, R. Mohan and C.E. Brinckerhoff
Quotes and reviews
@qu:"It is an encyclopedia and up-to-date compendium of the minute details of the literature on all characterized MMPs for specialists in this field... would I buy it? Yes."
@qu:"In all, this book is a very comprehensive coverage of the specialized area of MMPs. The editors and contributors describe not only the current status of research being conducted in this field, but also speculate on the future direction of that research."
@source:--DOODY'S PUBLISHING REVIEWS