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Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects provides a comprehensive view of the biochemistry, biological activity, and practical applicati… Read more
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Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects provides a comprehensive view of the biochemistry, biological activity, and practical application of extracellular glycolipids of yeast. This book brings much-needed clarity to the complex topic of glycolipids and streamlines the rather confusing terminology used for glycolipids. It also provides a wealth of modern data on their composition, structure and properties, biosynthetic pathways, methods of isolation and identification, antifungal activity, and mechanisms of action.
Studies of extracellular glycolipids of yeast now draw the attention of researchers in life science and biotechnology due to numerous recently revealed biological properties of these compounds. These compounds are scientifically and practically promising in medicine and agriculture due to their biosurfactant and fungicidal properties, as well as a number of other biological activities. Extracellular Glycolipids of Yeasts gives researchers studying biochemistry of microorganisms and related biologically active compounds a much-needed guide to the basic data that will aid in these increasingly generative pursuits.
Chapter 1. Structure and Occurrence of Yeast Extracellular Glycolipids1.1 The Structures of Extracellular Glycolipids of Yeast1.2 Glycolipid Occurrence in Eumycetes
Chapter 2. Methods for Studying Yeast Extracellular Glycolipids2.1 Culture Media and Methods for Increasing the Yield of Yeast Extracellular Glycolipids2.2 Purification Methods2.3 Thin-Layer Chromatography Systems for Glycolipid Detection2.4 Chemical Methods2.5 NMR Spectroscopy and Mass Spectrometry2.6 Methods for Studying Physicochemical Properties and Antifungal and Membrane-Damaging Activities2.7 Molecular Biology Methods
Chapter 3. Physicochemical Properties of Yeast Extracellular Glycolipids3.1 Solubility3.2 Stability During Storage and thermal Stability3.3 Molecular Masses3.4 Surface-Active Properties3.5 Lactonization and Self-Assembly3.6 Interaction Between Cellobiose Lipids and Artificial Membranes
Chapter 4. Biological Activities of Extracellular Yeast Glycolipids4.1 Antifungal Activity of Cellobiose Lipids4.2 Membrane-Damaging Activity of Cellobiose Lipids4.3 Biological Activities of MELs and Sophorolipids4.4 The Biological Activities of Rare Fungal Glycolipids4.5 The Role of Extracellular Glycolipid for Yeast Producers
Chapter 5. Metabolism of Yeast Extracellular Glycolipids5.1 Biosynthesis of Extracellular Glycolipids5.2 Catabolism of Extracellular Glycolipids
Chapter 6. Prospects of Practical Application of Sophorolipids, Cellobiose Lipids, and MELs6.1 Application as Membranotropic Agents6.2 Prospects of Application of Yeast Extracellular Glycolipids in Industry, Agriculture, and Medicine6.3 Commercial Products Based on Yeast Extracellular Glycolipids
Appendix. Selected Techniques of Purification and Assay of Extracellular Yeast GlycolipidsA.1 Methods for Cultivating Producers and Obtaining GlycolipidsA.2 Methods of Antifungal Activity AssayA.3 Methods of Membrane-Damaging Activity Assay
EK
Mr.Sci: July 2005 in Biology (Pushchino State University)
Ph.D.: November 2006 in Biochemistry (Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences): Antifungal yeast glycolipids. (Supervisors Prof. Kulaev, I.S., and Dr. W.I.Golubev Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences)
Positions held:
2005-2008: Junior Researcher, Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences
2008-Present: Researcher Skryabin Institute of Biochemistry and Physiology of Microorganisms
TK
Mr.Sci: July 1979 in Biochemistry (Moscow State University, 1979)
Ph.D.: Marh 1985 in Biochemistry (Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences): ATPase and ion transport in yeast vacuoles. (Supervisor Prof. Kulaev, I.S., Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences)
Dr. Sci. in Biochemistry (December, 2001) (Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences): Exopolyphosphatases of Saccharomyces cerevisiae
Positions held:
1984-1989 Junior Researcher, Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences
1989-1992 Researcher Skryabin Institute of Biochemistry and Physiology of Microorganisms
1993-2004 Senior Researcher, Skryabin Institute of Biochemistry and Physiology of Microorganisms
2004-2005 Leading Researcher, Skryabin Institute of Biochemistry and Physiology of Microorganisms
2005-Present: Head of Laboratory of Regulation of Biochemical Processes Skryabin Institute of Biochemistry and Physiology of Microorganisms