Molecular Pathology of Pituitary Adenomas

Molecular Pathology of Pituitary Adenomas, 1st Edition

Molecular Pathology of Pituitary Adenomas, 1st Edition,Cristiana Tanase,Irina Ogrezeanu,Corin Badiu,ISBN9780124158306

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Provides a synthesis of the latest developments in the field

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Key Features

  • Facilitates the understanding of the processes involved and how they are translated into therapy
  • Illustrations are used to explain the complex mechanisms involved


The pituitary gland is an important one since it controls several of the other hormone glands, such as the thyroid and adrenals. A pituitary adenoma is an abnormal growth or tumor in this gland, and they are the subject of very active clinical and pathological research.

This book examines the latest developments in this field and discusses the most important molecules implicated in apoptosis, angiogenesis and signal transduction. A good understanding of these processes is needed to identify the best therapies.


Pathologists, clinical endocrinologists, neurosurgeons, basic scientists

Cristiana Tanase

Affiliations and Expertise

Victor Babes National Institute of Pathology, Bucharest, Romania

Irina Ogrezeanu

Affiliations and Expertise

"D. Bagdasar" Hospital, Bucharest, Romania

Corin Badiu

Affiliations and Expertise

"C.Davila" University of Medicine and Pharmacy and Institute of Endocrinology, Bucharest, Romania

Molecular Pathology of Pituitary Adenomas, 1st Edition

1. Pituitary tumor classification: functionality, invasiveness, aggressiveness

Irina Ogrezeanu, Corin Badiu, Cristiana Tanase, Alina Neagoe

2. Immunohistochemistry and electron microscopy as evaluation criteria in tumour classification in the deciphering of pituitary adenomas

Corin Badiu, Irina Ogrezeanu, Cristiana Tanase

3. Proliferation

Cristiana Tanase and Radu Albulescu

4. Angiogenesis

Cristiana Tanase, Elena Codrici, Irina Radu, Simona Mihai

5. Apoptosis

Cristiana Tanase, Radu Albulescu

6. Signal transduction

Cristiana Tanase, Monica Neagu, Radu Albulescu, Linda Maria Cruceru, Adrian Popa

7. Stem cells markers in pituitary adenomas

Corin Badiu, Cristiana Tanase, Linda Maria Cruceru

8. microRNAs

Cristiana Tanase, Radu Albulescu, Lucian Albulescu

9. New generic tools for diagnosis: genomics, proteomics

Cristiana Tanase, Radu Albulescu, Ionela Daniela Popescu

10. Therapeutic approach: drug, surgical and radiotherapy

Cristiana Tanase, Irina Ogrezeanu

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