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Advances in Clinical Chemistry
 
 

Advances in Clinical Chemistry, 1st Edition

 
Advances in Clinical Chemistry, 1st Edition,Gregory Makowski,ISBN9780124076815
 
 
 

Advances in Clinical Chemistry

G Makowski   

Academic Press

9780124076815

9780124078062

224

229 X 152

Volume 60 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology

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Key Features

  • Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology

Description

Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology.

Readership

Biochemists and clinical biochemists

Gregory Makowski

Dr Gregory S Makowski is a board certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in his joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President and Chief Scientific Officer for Clinical Laboratory Partners in Newington CT, USA.

Affiliations and Expertise

Clinical Laboratory Partners, Newington; Hartford Hospital, Hartford; Department of Laboratory Medicine, University of Connecticut Health Center, Farmington, CT, USA

View additional works by Gregory S. Makowski

Advances in Clinical Chemistry, 1st Edition

Contributors

Preface

Chapter One. Folate and B12 in Prostate Cancer

Abstract

Abbreviations

1 Introduction

2 Prostate Cancer

3 Folate, B12, and One-Carbon Metabolism

4 Pathways and Mechanisms

5 Folate and Prostate Cancer

6 Vitamin B12 and Prostate Cancer

7 Homocysteine, Methionine, and Betaine

8 Folic Acid and B12 Supplements

9 Genetic Epidemiology

10 Conclusions

Acknowledgment

References

Chapter Two. Mismatch Repair Proteins in Recurrent Prostate Cancer

Abstract

Abbreviations

1 Mismatch Repair Proteins in Repair

2 MMR Proteins in DNA Damage Response

3 MMR Proteins in Cancer

4 MMR Proteins in Prostate Carcinogenesis

5 MMR Proteins: Role in Treatment Response?

6 Conclusions

Acknowledgments

References

Chapter Three. Protein Antioxidants in Thalassemia

Abstract

1 Introduction

2 Normal Iron Metabolism

3 Iron Metabolism in Thalassemia

4 Oxidative Stress in Thalassemia

5 Antioxidative Status in Thalassemia

6 Antioxidative Therapeutic Trials

7 Future Directions and Concluding Remarks

Acknowledgments and Conflict of Interest

References

Chapter Four. Immune Complexome Analysis

Abstract

Abbreviations

1 Immune Complex

2 Identification of Disease-Associated Antigens

3 Immune Complexome Analysis of RA Patients

4 Conclusion

References

Chapter Five. Genetics of Gallstone Disease

Abstract

Abbreviations

1 Genetic Background of Human Cholesterol Gallstones

2 Pathophysiology of Gallstone Formation

3 Candidate Genes Involved in Regulation of Biliary Cholesterol Secretion

4 Mucin Gene

5 Gallbladder Motility

6 Conclusion

References

Chapter Six. Glycoprotein 2 Antibodies in Crohn’s Disease

Abstract

Abbreviations

1 Crohn’s Disease and Pancreatic Autoreactivity

2 Identification of GP2 as the Main Autoantigenic Target of PAB

3 Biochemistry of Glycoprotein 2

4 Physiology of Glycoprotein 2

5 Possible Role of Glycoprotein 2 in Pathophysiology

6 Anti-GP2 Autoantibodies in the Serology of IBD

References

Index

 
 
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