Diabetes, 1st Edition

Oxidative Stress and Dietary Antioxidants

Diabetes, 1st Edition,Victor Preedy,ISBN9780124058859

V Preedy   

Academic Press




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Translational coverage of how dietary antioxidants and oxidative stress contribute to and protect from diabetes and diabetic complications

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Key Features

  • Nutritionists will use the information related to mitochondrial oxidative stress in one disease and propose new diet-related strategies to prevent such conditions arising in another unrelated disease.
  • Dietitians will prescribe new foods or diets containing antioxidants for conditions that are refractory by conventional pharmacological treatments.
  • Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams.
  • Nutritionists and dietitians will learn about cell signaling and will be able to suggest preventive or therapeutic strategies with antioxidant-rich foods to reduce damage done by diseases involving abnormal cell signaling.


Diabetes: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide among diabetologists, endocrinologists, and nutritionists in understanding and treating diabetes. The book covers, in a single volume, the science of oxidative stress in diabetes and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, receptor-mediated responses and more. This approach recognizes that diseases are usually multifactorial and that oxidative stress is a single component of this.

Pharmacological treatments for diabetes are commonly marked by unwanted side effects, leading to treatment efforts using naturally occurring substances. But a plant-based approach alone is not sufficient; understanding the processes inherent in the oxidative stress of diabetes is vital for clinical workers, dietitians, and nutritionists.

This translational work provides that understanding. The book begins by covering the basic biology of oxidative stress from molecular biology to imaging in relation to diabetes. There are chapters on neuropathy, nephropathy, atherosclerosis, cardiomyopathy, and retinopathy. The book then moves on to antioxidants in foods, including plants, components of the diet, and their relevance to diabetes.


Nutritionists, dieticians, diabetologists, endocrinologists, and researchers across these areas

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FSB, FRSH, FRIPH, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the multi-volume seminal work The Handbook Of Alcohol Related Pathology (published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Department of Dietetics, King's College London, UK

View additional works by Victor R. Preedy

Diabetes, 1st Edition

Oxidative Stress and Diabetes

  1. Oxidative stress and diabetic neuropathy
    Y. Park, Department of Internal Medicine and Bioengineering, Hanyang University, Seoul, South Korea
  2. Oxidative stress in diabetic nephropathy
    Prof. A.A. Elmarakby, Medical College of Georgia, Augusta, GA, United States
  3. Oxidative stress in diabetic atherosclerosis
    Prof. M. Nowicki, Institute of Anatomy, University of Leipzig, Leipzig, Germany
  4. Diabetic stroke and oxidative stress
    Prof. K. R. Dave, Cerebral Vascular Disease Research Center, University of Miami, Department of Neurology, Miami, FL, United States
  5. Diabetic cardiomyopathy and oxidative stress
    Prof. K. Watanabe, Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Niigata City, Japan
  6. Oxidative stress in diabetic retinopathy
    Prof. G. B. Arden, Henry Wellcome Research Laboratories, Centre for Applied Vision Sciences, Department of Optometry and Visual Science, City University, London, UK
  7. Antioxidants and Diabetes

  8. Beta glucan and neuroprotection in diabetes
    Prof. H. Alp, Department of Pharmacology and Toxicology, Veterinary Faculty, Dicle University, Diyarbakir, Turkey
  9. Selenium and diabetic peripheral neuropathy
    Prof. M. Ayaz, Department of Biophysics, Selcuklu Medical Faculty, Selcuk University, Konya, Turkey
  10. Neuropathy and micronutrients supplementation
    Prof. M.S. Farvid, Department of Community Nutrition, National Nutrition and Food Technology Research Institute, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
  11. Nigella sativa oil, diabetic neuropathy and oxidative stress
    Prof. M. Akhtar, Department of Pharmacology, Hamdard University, New Delhi, India
  12. Diabetic nephropathy, propolis and oxidative stress
    Prof. O. M. Abo-Salem, Phamacology and Toxicology Departments, Al-Azahar University, Cairo, Egypt
  13. Green tea, oxidative stress and diabetic nephropathy
    Prof. H. H. Kim, Department of Urology, Seoul National University College of Medicine, Seoul, South Korea
  14. Diabetic nephropathy and tocotrienol
    Prof. K. Chopra, Pharmacology Research Laboratory, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Chandigarh, India
  15. Resveratrol, diabetic nephropathy and oxidative stress
    Prof. L.-M. Hung, Department and Graduate Institute of Biomedical Sciences, Chang Gung University, Tao-Yuan, Taiwan (Republic of China)
  16. Anti-RAGE compounds, atherosclerosis and diabetes
    Prof. K.A.M. Jandeleit-Dahm, Diabetes Division, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
  17. Vitamin E and vascular protection in diabetes
    Prof. A.P. Levy, Department of Anatomy and Cell Biology, Technion Israel Institute of Technology, Haifa, Israel
  18. Ginkgo biloba, atherosclerosis protection in diabetes
    Prof. K. S. Park, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea
  19. Zinc supplementation and oxidative stress of vascular tissues Prof. R.C.S. Seet, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
  20. Taurine and cardiac oxidative stress
    Prof. P.C. Sil, Division of Molecular Medicine, Bose Institute, West Bengal, India
  21. Statins, diabetic oxidative stress and vascular tissue
    Prof. J.R. Murrow, Emory University School of Medicine, Atlanta, GA, United States
  22. Herbal Chrysanthemi Flos, oxidative damage and diabetic vascular protection
    Prof. S.-J. Kim, Department of Pharmacology and Toxicology and Metabolic Diseases Research Laboratory, Kyung Hee University, Seoul, South Korea
  23. Antioxidant supplements and diabetic retinopathy
    Prof. J. J. Garcia-Medina, Ophthalmology Research Unit Santiago Grisolia, University Hospital Doctor Peset, Valencia, Spain
  24. Neuroprotective lutein in the retina
    Prof. Y. Ozawa, Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan
  25. Anti-oxidant related micronutrients and diabetic retinopathy
    Prof. A.I. Adler, MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
  26. Resveratrol, oxidative stress and diabetic liver
    Prof. R. Schmatz, Departamento de Quimica, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil
  27. Pomegranate juice, oxidative stress and the lung in diabetes
    Prof. G. Eren, Bakirkoy, Dr. Sadi Konuk Training and Research Hospital, Department of Anesthesiology and Intensive Care, Istanbul, Turkey
  28. Rosemary extract in diabetes
    Prof. C. Barbas, CEMBIO, Universidad San Pablo-CEU, Madrid, Spain
  29. Antioxidative effects of allium cepa in diabetes
    Prof. N. A. El-soud, National Research Center, Complementary Medicine, Cairo, Egypt
  30. Citrus flavonoids and oxidative stress in diabetes
    Prof. L. Pari, Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Tamilnadu, India
  31. Oxidative stress, diabetes and iron
    Prof. S.R. Marcus, MSU-GEF International Medical School, Bangalore, India
  32. Gingseng, diabetes and and oxidative stress
    Prof. K. A. Amin, Department of Biochemistry, Faculty of Veterinary Medicine, Beni-Suef University, Beni Suef, Egypt

Quotes and reviews

"Each volume in the Oxidative Stress and Dietary Antioxidants series focuses on the phenomena in a single organ, disease, or pathology. Diabetes takes the spotlight here, with discussions of such matters as mitochondrial oxidative stress in diabetes, antioxidant spices and herbs used in diabetes…The material is for dietitians and nutritionists, food scientists, health care workers, and researchers."--ProtoView.com, February 2014
"The book is written for both practitioners and scientists studying this topic… It is a useful reference for practitioners wanting to expand their available treatment options…This is a comprehensive review of the mechanisms leading to diabetic complications with a specific focus on oxidative stress as well as an important review of antioxidant therapies that have been studied in the diabetic population." Rating: 3 Stars--Doody.com, February 21, 2014

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