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Bioactive Food as Dietary Interventions for Cardiovascular Disease
 
 

Bioactive Food as Dietary Interventions for Cardiovascular Disease, 1st Edition

Bioactive Foods in Chronic Disease States

 
Bioactive Food as Dietary Interventions for Cardiovascular Disease, 1st Edition,Ronald Ross Watson,Victor Preedy,ISBN9780123964854
 
 
 

Watson   &   Preedy   

Academic Press

9780123964854

9780123965400

746

240 X 197

Investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease.

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Key Features

  • Addresses the most positive results from dietary interventions using bioactive foods to impact cardiovascular disease
  • Documents foods that can affect metabolic syndrome and other related conditions
  • Convenient, efficient and effective source that allows readers to identify potential uses of compounds – or indicate those compounds whose use may be of little or no health benefit
  • Associated information can be used to understand other diseases that share common etiological pathways

Description

One major example of the synergy of bioactive foods and extracts is their role as an antioxidant and the related remediation of cardiovascular disease. There is compelling evidence to suggest that oxidative stress is implicated in the physiology of several major cardiovascular diseases including heart failure and increased free radical formation and reduced antioxidant defences. Studies indicate bioactive foods reduce the incidence of these conditions, suggestive of a potential cardioprotective role of antioxidant nutrients.

Bioactive Food as Dietary Interventions for Cardiovascular Disease investigates the role of foods, herbs and novel extracts in moderating the pathology leading to cardiovascular disease. It reviews existing literature, and presents new hypotheses and conclusions on the effects of different bioactive components of the diet.

Readership

Nutritionists, dieticians, and biomedical researchers whose focus is on identifying cardiovascular and related diseases; food scientists targeting health-related product development.

Ronald Ross Watson

Ronald R. Watson, Ph.D., attended the University of Idaho but graduated from Brigham Young University in Provo, Utah, with a degree in chemistry in 1966. He earned his Ph.D. in biochemistry from Michigan State University in 1971. His postdoctoral schooling in nutrition and microbiology was completed at the Harvard School of Public Health, where he gained 2 years of postdoctoral research experience in immunology and nutrition. From 1973 to 1974 Dr. Watson was assistant professor of immunology and performed research at the University of Mississippi Medical Center in Jackson. He was assistant professor of microbiology and immunology at the Indiana University Medical School from 1974 to 1978 and associate professor at Purdue University in the Department of Food and Nutrition from 1978 to 1982. In 1982 Dr. Watson joined the faculty at the University of Arizona Health Sciences Center in the Department of Family and Community Medicine of the School of Medicine. He is currently professor of health promotion sciences in the Mel and Enid Zuckerman Arizona College of Public Health. Dr. Watson is a member of several national and international nutrition, immunology, cancer, and alcoholism research societies. Among his patents he has one on a dietary supplement; passion fruit peel extract with more pending. He continues to do research in animals and in clinical trials on dietary supplements and health including studies using omega-3 fatty acids in heart disease prevention and therapy. For 30 years he was funded by Wallace Research Foundation to study dietary supplements in health promotion. Dr. Watson has edited more than 110 books on nutrition, dietary supplements and over-the-counter agents, and drugs of abuse as scientific reference books. He has published more than 500 research and review articles.

Affiliations and Expertise

Health Promotion Sciences Department, Mel and Enid Zuckerman College of Public Health, and School of Medicine, University of Arizona, Tucson, AZ, USA

View additional works by Ronald Ross Watson

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FSB, FRSH, FRIPH, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the multi-volume seminal work The Handbook Of Alcohol Related Pathology (published by Academic Press-Elsevier). Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Department of Dietetics, King's College London, UK

View additional works by Victor R. Preedy

Bioactive Food as Dietary Interventions for Cardiovascular Disease, 1st Edition

Acknowledgments for Bioactive Foods in Chronic Disease States

Preface: Bioactive Food for Cardiovascular Disease

Contributors

Chapter 1. Omega-3 Fatty Acids in Prevention of Cardiovascular Disease in Humans: Intervention Trials, Healthy Heart Concept, Future Developments

1 Introduction

2 Role of Omega-3 Fatty Acids in CVD

3 Modern View of Omega Fatty Acid Therapy in CVD

4 Healthy Heart Concept: Less-Known Facts on Omega Fatty Acids

5 Guidelines on Omega Fatty Acid in CVD to Physicians, Nurses: Healthy Heart Concept

6 Implications and Futuristic Prospective

7 Conclusions

Acknowledgments

References

Chapter 2. Herbal Supplements or Herbs in Heart Disease: History, Herbal Foods, Coronary Heart Disease

1 Introduction

2 Relation to TG Metabolism

3 Herbal Foods: Approved Herbs in Cardiovascular Disease

4 Repertory of Herbs and Their Properties

5 Herbs in Human Use

6 Cardioprotective Herb Active Components in Human Use Approved by CDC and Regulated by FDA

7 Conclusion

Acknowledgments

References

Chapter 3. Plant Statins and Heart Failure

1 Heart Failure

2 Statins in the Treatment of HF

3 Complementary Medicine in Heart Failure

4 Plant Sterols/Stanols (Phytosterols)

5 Conclusion

References

Chapter 4. Bioactive Nutrients and Cardiovascular Disease

1 Bioactive Nutrients

References

Chapter 5. Vitamins and Myocardial Infarction in Diabetics

Abbreviations

1 Introduction

2 Patients with Myocardial Infarction and DM Are at Particular Risk

3 Importance of OS in Myocardial Infarction

4 Importance of OS in DM

5 Antioxidant Effect of Vitamins

6 Summary

References

Chapter 6. Cardioprotective Nutrients

1 Introduction

2 Cardioprotective Nutrients

3 Conclusion

References

Relevant Websites

Chapter 7. Fruit and Vegetable Consumption and Risk of Noncommunicable Diseases

Abbreviations

1 Introduction

2 FV and CVD

3 FV and Diabetes Mellitus

4 FV and MetS

5 FV and Hypertension

6 FV and Obesity

7 FV and Bone Mineral Status

8 FV and Cancer

9 Prevention of Noncommunicable Disease by FV Intake

10 Conclusion

References

Relevant Websites

Chapter 8. Diet and Homocysteinemia: A Role in Cardiovascular Disease?

Abbreviations

1 Introduction

2 Homocysteine

3 Homocysteinemia

4 Future Perspectives

References

Chapter 9. Phytosterols and Cardiovascular Disease

Abbreviations

1 Introduction

2 Phytosterols in the Diet

3 Plasma Phytosterols and CVD

4 Phytosterol Mechanism of Action

5 Physical Factors Affecting Phytosterol LDL Lowering

6 Biological Factors Affecting Response to Phytosterols

7 Phytosterols and Pharmaceutical Cholesterol Lowering Therapies

8 Phytosterols, MetS, and Diabetes

9 Phytosterols and Triglyceride Lowering

10 Phytosterols and CVD Risk Reduction

11 Conclusion

12 Summary Points

Glossary

References

Chapter 10. Taurine Effects on Arterial Pressure Control

Abbreviations

1 An Overview of Arterial Pressure Control

2 Physiology of Taurine

3 Taurine and Perinatal Development

4 Taurine and the Heart

5 Taurine and the Autonomic Nervous System

6 Perinatal Taurine and Arterial Pressure Control

7 Adult Taurine Exposure and Hypertension

8 Taurine and the Kidney

9 Summary

References

Chapter 11. Fish Consumption and Risk of Cardiovascular Disease – Part 1

Abbreviations

1 Introduction

2 All-Cause Mortality

3 Coronary Heart Disease Mortality

4 Coronary Heart Disease Prevention

References

Relevant Websites

Chapter 12. Fish Consumption and Risk of Cardiovascular Disease – Part 2

Abbreviations

1 Heart Failure – Left Ventricular Systolic Dysfunction

2 Stroke Prevention

3 Pathophysiological Mechanisms

4 Methodological Problems

5 Fish Contaminants

6 Dietary Guidelines

7 Conclusion

References

Relevant Websites

Chapter 13. Quercetin and Its Metabolites in Heart Health

1 Quercetin: Chemistry and Bioavailability

2 Cardiovascular Disease and Quercetin

3 Safety of Quercetin

Glossary

References

Further Reading

Chapter 14. Vitamin K, Coronary Calcification and Risk of Cardiovascular Disease

1 Vitamin K

2 Vitamin K and Arterial Calcification

3 Vitamin K Intake and Risk of Coronary Heart Disease

4 Vitamin K Intake and Risk of Stroke

5 Conclusion

References

Chapter 15. A Review of the Antioxidant Actions of Three Herbal Medicines (Crataegus monogyna, Ginkgo biloba, and Aesculus hippocastanum) on the Treatment of Cardiovascular Diseases

1 Introduction

2 Hawthorn

3 Ginkgo

4 Horse Chestnut Seed

5 Concluding Statements

6 Summary

Glossary

References

Further Reading

Relevant Websites

Chapter 16. Grape Polyphenols in Heart Health Promotion

1 Introduction

2 Grape Chemistry and Bioavailability

3 Human Studies – Cardiovascular Effects

4 Potential Mechanisms of Effect

5 Translational Frontiers

References

Chapter 17. Cacao for the Prevention of Cardiovascular Diseases

Abbreviations

1 Introduction

2 Dietary Antioxidants

3 The Role of Tryptophan Metabolism and Neopterin Formation in Cardiovascular Disease

4 Cacao to Enhance Mood

5 Conclusion

References

Chapter 18. Phytoestrogens and the Role in Cardiovascular Health: To Consume or Not to Consume?

Abbreviations

1 Background and Significance

2 Phytoestrogens and Biology, Chemistry, and Pharmacokinetics

3 Biological Modes of Action: Estrogenic, Antiestrogenic, and ER Independent Modes of Action

4 Phytoestrogens and Cardiovascular Health

5 Confounding Factors to Consider

6 Summary and Concluding Remarks

Acknowledgments

References

Chapter 19. Probiotic Species on Cardiovascular Disease: The Use of Probiotics to Reduce Cardiovascular Disease Risk Factors

Abbreviations

1 Introduction

2 Hypocholesterolemic Effect of Probiotics

3 Mechanism of Hypocholesterolemic Effect of Probiotics

4 Hypotensive Effect of Fermented Milk Product

5 Mechanisms of Blood Pressure Lowering

6 Alternative Targets of Bioactive Peptides

7 Effects of Peptides Other Than Blood Pressure-lowering Effect

8 Lipopolysaccharide (LPS), Inflammation, CVD, and Probiotics

9 Improving Insulin Resistance Associated with Inflammation

10 Conclusions and Future Directions

Acknowledgments

References

Chapter 20. Dairy Foods and Cardiovascular Diseases

Abbreviations

1 Prevalence of Cardiovascular Diseases in the United States

2 Mechanism of Inflammation

3 Role of Selected Foods in the Prevention of Inflammation in CVD

4 Summary

References

Chapter 21. Red Palm Oil Carotenoids: Potential Role in Disease Prevention

Abbreviations

1 Background

2 Carotenoid Content of RPO

3 Biological Significance of Dietary Carotenoids

4 Carotenoids in Health and Disease

5 Safety of Carotenoids from Natural Food Sources

6 Nutritional Value of RPO

References

Further Reading

Chapter 22. Bioactive Compounds in Red Palm Oil Can Modulate Mechanisms of Actions in In Vitro Anoxic Perfused Rat Hearts

1 Introduction

2 Involvement of the Prosurvival and Apoptotic Pathways in Red Palm Oil Protection

3 Involvement of the NO-CGMP Pathway and MMP in Red Palm Oil Protection

4 Optimal Feeding Period and Dosage of Red Palm Oil to Offer Protection Against Anoxia

5 Red Palm Oil Protection in Other Disease Models

6 Summary

References

Chapter 23. The Effect of L-Carnitine Supplement and Its Derivatives on Cardiovascular Disease

Abbreviations

1 Introduction

2 The Effect of LC and its Derivates on the Cardiovascular Risk Factors

3 The Effect of LC and its Derivatives on Patients with Atherosclerosis

4 The Effect of LC and its Derivatives on Patients with Congestive Heart Failure/Cardiomyopathy

References

Chapter 24. Dietary Blueberry Supplementation as a Means of Lowering High Blood Pressure

Abbreviations

1 Hypertension

2 Conventional Treatment of Hypertension

3 Treatment of Hypertension Through Functional Foods and Phytochemicals

4 Conclusion

Glossary

References

Further Reading

Relevant Websites

Chapter 25. Vitamin D and Cardiometabolic Risks

Abbreviations

1 Introduction

2 The Metabolic Syndrome

3 IR, Diabetes, and Vitamin D

4 Overweight, Obesity, and Vitamin D

5 Lipoproteins and Vitamin D

6 Hypertension

7 CVD and Vitamin D

8 Final Remarks

Glossary

References

Further Reading

Chapter 26. Phytosterols and Micronutrients for Heart Health

Abbreviations

1 Introduction

2 Micronutrients

3 Phytosterols

4 Conclusion

References

Chapter 27. Protection by Plant Flavonoids Against Myocardial Ischemia–Reperfusion Injury

Abbreviations

1 Introduction

2 Flavonols

3 Flavanols

4 Proanthocyanidins

5 Flavanones

6 Flavones

7 Isoflavones

8 Anthocyanins

9 Conclusions

References

Chapter 28. Bioactive Compounds in Heart Disease

1 Introduction

2 Flavonoids

3 Phytoestrogens

4 Resveratrol

5 Carotenoids

6 Organosulfur Compounds

7 Polyunsaturated Fatty Acids

8 Conclusion

Relevant Website

References

Chapter 29. A Critical Appraisal of the Individual Constituents of Indian Diet in Modulating Cardiovascular Risk

1 Introduction

2 The Indian Diet and Cuisine

3 Cereals

4 Pulses

5 Nuts

6 Dry Fruits

7 Spices

8 Fruits and Vegetables

9 Oils and Fats

10 Fish and Fish Oils

11 Milk and Dairy Products

12 Sweets and Desserts

13 Meat and Meat Products

14 Egg and Egg Products

15 Consideration of High Salt Intake in India

16 Micronutrients and Cardiac Health

17 Conclusions

Acknowledgments

References

Chapter 30. Omega-3 Fatty Acids in Prevention of Cardiovascular Disease in Humans: Chemistry, Dyslipidemia

1 Introduction

2 Omega Fatty Acids and Dyslipidemia

3 Mechanism of Lipid Lowering and Cardioprotection by Omega-3 Fatty Acid Intake

4 Conclusion

Acknowledgments

References

Chapter 31. Herbal Supplements or Herbs in Heart Disease: Herbiceutical Formulation, Clinical Trials, Futuristic Developments

1 Introduction

2 Herbiceutical Formula in Heart Disease Treatment

3 Herbiceutical Testing

4 Cardioprotective Herbal Active Components in Human Use Approved by CDC and Regulated by FDA

5 Pharmaceutical Approach of Herbiceutical Formula with Antiarrhythmic Properties

6 Treatment Recommendations for Herbiceuticals in Cardiovascular Prevention

7 Conclusion

Acknowledgments

References

Chapter 32. Fish Proteins in Coronary Artery Disease Prevention: Amino Acid–Fatty Acid Concept

1 Introduction

2 Fish Proteins and Amino Acids

3 Fish Proteins in Cardiac Prevention

4 Effect of Fish Dietary Proteins on Coronary Artery Disease

5 Effect of Fish Proteins on Atherosclerosis

6 Prevention of CAD: Fish Diet

7 Conclusion

Appendix 1 New method developed: SDS-PAGE electrophoresis

References

Chapter 33. Herbs Used in Traditional Chinese Medicine in Treatment of Heart Diseases

Abbreviations

1 Introduction

2 TCM Herbs

3 Discussion

References

Chapter 34. Protective Effect of Garlic (Allium sativum L.) Against Atherosclerosis

Abbreviations

1 Introduction

2 Etiopathogenesis of Atherosclerosis

3 Prevention of Atherosclerosis

4 Plants in the Prevention of Atherosclerosis

5 Allium sativum

6 Bioactive Compounds in Garlic

7 Protective Effect of Garlic Against Atherosclerosis

8 Conclusions

Acknowledgment

References

Chapter 35. Potential of Soy Phytochemicals in Cardiomyocyte Regeneration and Risk Reduction of Coronary Heart Disease

Abbreviations

1 Introduction and Overview

2 Pathogenesis of CHD

3 Cardiomyocyte Regeneration

4 Soy Phytochemicals and Cardioprotection

5 Role of soy Isoflavones in Control of Cardiomyocyte Proliferation, Cell Cycle Reentry, and Regeneration

6 Conclusion and Future Studies

Acknowledgments

References

Chapter 36. Fish Oil Fatty Acids and Vascular Reactivity

Abbreviations

1 Introduction

2 Observational Studies Examining the Relationship Between Habitual LC n-3 PUFA Intake with Carotid IMT and Vascular Reactivity

3 Chronic Studies Examining the Impact of LC n-3 PUFA Supplementation on Vascular Function

4 Acute Studies Examining the Effects of LC n-3 PUFA on Postprandial Vascular Reactivity

5 Potential Mechanisms

6 Conclusions

References

Relevant Website

Chapter 37. Counteracting the Inflammatory Response in the Atherosclerosis Bioactive Products

1 Introduction

2 Inflammatory Mechanisms in Atherosclerosis

3 Low-Density Lipoprotein

4 Oxidative Stress and Vascular Function

5 Antioxidants – Protective Role in CVD

6 Concluding Remarks

References

Chapter 38. Cardioprotective Efficacy of Alternative and Complementary Therapeutics

1 Introduction

2 Acorus calamus

3 Aegle marmelos

4 Allium cepa

5 Allium sativum

6 Centella asiatica

7 Commiphora wightii

8 Emblica officinalis

9 Ocimum sanctum

10 Picrorhiza kurroa

11 Terminalia arjun

12 Terminalia chebula

13 Tinospora cordifolia

14 Withania somnifera

15 Zingiber officinale

16 Conclusions

Acknowledgments

References

Chapter 39. Effect of Terminalia arjuna on Cardiac Hypertrophy

Abbreviations

1 Terminalia arjuna: A Cardioprotective Plant

2 Terminalia arjuna and Cardiac Hypertrophy

3 Conclusion and Future Perspective

References

Chapter 40. Plant Sterols and Artery Disease

Abbreviations

1 What Are Plant Sterols?

2 Metabolism of Phytosterols in Humans

3 Plant Sterols and Artery Disease in Humans

4 Conclusions

References

Chapter 41. Antiatherogenic Effects of Ginger (Zingiber officinale Roscoe): Scientific Observations and Ethnomedicinal Validation

Abbreviations

1 Introduction

2 Etiopathogenesis of Atherosclerosis

3 Plants in the Prevention of Atherosclerosis

4 Protective Effects of Ginger Against Atherosclerosis

5 Conclusion

Acknowledgment

References

Index

 
 
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