Volume 64: Current State of Alzheimer's Disease Research and Therapeutics, 1st Edition

Key Features

• Explores the current state of Alzheimer's disease research and therapeutics
• Chapters cover a variety of topics such as the role heat shock proteins play in the Alzheimer's theater, gamma-secretase as a target for Alzheimer's disease, and identification of protein kinase C for the treatment of dementias
• With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike

Description

This new volume of Advances in Pharmacology explores the Current State of Alzheimer's Disease Research and Therapeutics. Chapters cover such topics as the The role heat shock proteins play in the Alzheimer's Theater, Gamma-Secretase as a Target for Alzheimer's Disease, and Identification of protein kinase C for the treatment of dementias. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

Readership

Pharmacologists, immunologists, and biochemists

Current State of Alzheimer's Disease Research and Therapeutics, 1st Edition

1. Hsp90 Modulation for the Treatment of Alzheimer’s Disease

Huiping Zhao, Mary L. Michaelis and Brian S. J. Blagg

2. Using Pittsburgh Compound B for In-vivo PET Imaging of Fibrillar Amyloid-beta

Ann D. Cohen, Gil D. Rabinovici, Chester A. Mathis, William J. Jagust, William E. Klunk and Milos D. Ikonomovic

3. Mitochondrial Abnormalities in Alzheimer's Disease: Possible Targets for Therapeutic Intervention

Diana F. Silva, J. Eva Selfridge, Jianghua Lu, Lezi E, Sandra M. Cardoso, and Russell H. Swerdlow

4. g-Secretase as a Target for Alzheimer’s Disease

Michael S. Wolfe

5. Altering Mitochondrial Dysfunction as an Approach to Treating Alzheimer’s Disease

Jerry R. Colca and Douglas L. Feinstein

6. scyllo-Inositol, Preclinical and Clinical Data for Alzheimers disease

Keran Ma, Lynsie A.M. Thomason and JoAnne McLaurin

7. Beyond Amyloid: The Future of Therapeutics for Alzheimer’s Disease

Rachel F Lane, Diana W Shineman, John W Steele, Linda (Bobbi) H Lee and Howard M Fillit

8. Activation of Protein Kinase C Isozymes for the Treatment of Dementias

Miao-Kun Sun and Daniel L. Alkon

9. STriatal Enriched Protein Tyrosine Phosphatase in Alzheimer’s Disease

Jian Xu, Pradeep Kurup, Angus C. Nairn and Paul J. Lombroso

10. Estrogen Regulation of Mitochondrial Bioenergetics: Implications for Prevention of Alzheimer’s Disease