Volume 69: Metal Transporters, 1st Edition

Key Features

• Field is cutting-edge and a lot of the information is new to research community
• Wide breadth of topic coverage
• Contributors of high renown and expertise

Description

This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others.

Readership

Researchers in biochemistry, molecular and cellular biology.

Metal Transporters, 1st Edition

1. Regulation of Copper Transporters in Human Cells

Nesrin M. Hasan and Svetlana Lutsenko

2. Transferrin Mediated Cellular Iron Delivery

Ashley N. Steere and Anne B. Mason

3. Structure, Function and Binding Selectivity and Stereoselectivity of Siderophore-Iron Outer Membrane Transporters

Isabelle J. Schalk, Gaëtan L. A. Mislin and Karl Brillet

4. Iron Transport Machinery of Human Cells: Players and their Interactions

Ningning Zhao and Caroline A. Enns

5. Structure and Function of Copper Uptake Transporters

Christopher R Pope, Adrian G Flores, Jack H Kaplan and Vinzenz M Unger

6. Toward a Molecular Understanding of Metal Transport by P_1B-Type ATPases

Amy C. Rosenzweig and José M. Argüello

7. Metal Export by CusCFBA, the Periplasmic Cu(I)/Ag(I) Transport System of E. coli

Tiffany D. Mealman, Ninian J. Blackburn and Megan M. McEvoy

8. Molecular Architecture and Function of ZnT Transporters

Taiho Kambe

9. The Cation Selectivity of the ZIP Transporters

Robert E. Dempski

10. Nramp: from Sequence to Structure and Mechanism of Divalent Metal Import

Mathieu FM. Cellier

11. Genetic and Biochemical Approaches for Studying the Yellow Stripe-Like (YSL) Transporter Family in Plants

Sarah S. Conte and Elsbeth L. Walker

12. Pathways of Arsenic Uptake and Efflux

Hung-Chi Yang, Hsueh-Liang Fu , Yung-Feng Lin and Barry P. Rosen

13. Extra Heme Uptake and the Challenges of Bacterial Cell Membranes

Aaron D. Smith and Angela Wilks

14. The Mechanisms of Mg²⁺ and Co²⁺ Transport by the CorA Family of Divalent Cation Transporters