Volume 116: Histone Deacetylase Inhibitors as Cancer Therapeutics, 1st Edition

Key Features

• Provides invaluable information on the exciting and fast-moving field of cancer research
• This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics"
• Outstanding and original reviews

Description

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics."

Histone Deacetylase Inhibitors as Cancer Therapeutics, 1st Edition

1. Histone Deacetylase Inhibitors Disrupt the Mitotic Spindle Assembly Checkpoint by Targeting Histone and Non-Histone Proteins

Brian Gabrielli and Mellissa Brown

2. Mechanisms of Resistance to Histone Deacetylase Inhibitors

Ju-Hee Lee, Megan L. Choy and Paul A. Marks

3. HDAC Inhibitors: Roles of DNA Damage and Repair

Carine Robert and Feyruz V. Rassool

4. HDAC Inhibitor Modulation of Proteotoxicity as a Therapeutic Approach in Cancer

David J. McConkey, Matthew White, and Wudan Yan

5. Intrinsic and Extrinsic Apoptotic Pathway Signaling as Determinants of Histone Deacetylase Inhibitor Anti-Tumor Activity

Geoffrey M Matthews, Andrea Newbold and Ricky W. Johnstone

6. Histone Deacetylase Inhibitors and Rational Combination Therapies

Steven Grant

7. HDAC Inhibitors and Chaperone Function

Rekha Rao, Siddhartha Ganguly, Suman Kambhampati and Kapil N. Bhalla