Advances in Planar Lipid Bilayers and Liposomes

Advances in Planar Lipid Bilayers and Liposomes, 1st Edition

Advances in Planar Lipid Bilayers and Liposomes, 1st Edition,Ales Iglic,ISBN9780123877208

Advances in Planar Lipid Bilayers and Liposomes

A Iglic   

Academic Press




229 X 152

Invited authors present the latest results in this exciting multidisciplinary field

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Key Features

  • Incorporates contributions from newcomers and established and experienced researchers
  • Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives
  • Serves as an indispensable source of information for new scientists


Advances in Planar Lipid Bilayers and Liposomes volumes cover a broad range of topics, including main arrangements of the reconstituted system, namely planar lipid bilayers as well as spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field.


Chemical Engineers, physical chemists, biologists and biochemists, biochemical engineers

Ales Iglic

Aleš Iglic received his B.Sc. and Ph.D. degrees in physics and M.Sc. degree in biophysics from the Department of Physics, and the Ph.D. degree in electrical engineering from the Faculty of Electrical Engineering, all from the University of Ljubljana. He is a Full Professor and the Head of Laboratory of Biophysics of the Faculty of Electrical Engineering at University of Ljubljana. His main research interests are in electrostatics, mechanics and statistical physics of lipid nanostructures and biological membranes. He is devoted to higher education, basic research in biophysics and close contacts to clinical practice. Prof. Iglic was visiting scientist and professor at Åbo Academy University in Turku (Finland), Friedrich Schiller University in Jena (Germany) and Czech Technical University in Prague (Czech Republic). He established collaborations with researchers from different universities across the Europe, USA and India and was supervisor of many M.Sc., Ph.D. and postdoctoral students from Slovenia, Czech Republic, Poland, Iran, Bulgaria, Germany, India and Israel. Since 2009 is the editor of Elsevier book series »Advances in Planar Lipid Bilayers and Liposomes« (APLBL).

Affiliations and Expertise

Faculty of Electrical Engineering, University of Ljubljana, Slovenia

View additional works by Ales Iglic

Advances in Planar Lipid Bilayers and Liposomes, 1st Edition

Series Page



Chapter one: Faceting of Soft Crystals

1 Introduction

2 Experimental Methods

3 Faceting of Cubic/Vapor Interfaces

4 Faceting of Cubic/L1 Interfaces

5 Faceting in the Ternary and Quaternary Mixtures

6 Faceting and Topology

7 Phenomena Out of Equilibrium

8 Exploring Facets of Soft Crystals with AFM

9 Conclusions

Chapter two: How to Make a Stable Exocytotic Fusion Pore, Incompetent of Neurotransmitter and Hormone Release from the Vesicle Lumen?

1 Introduction

2 Narrow Fusion Pores Are Stable Due to the Accumulation of Anisotropically Shaped Molecules in the Highly Curved Membrane Regions

3 Isotropic Membrane Constituents Are Unable to Generate Narrow Stable Fusion Pores?

4 Protein and Lipids Affect Exocytosis and Fusion Pore Properties

5 SNARE Zippering and SM-Proteins

6 Cytosolic Plasma Membrane PIP2 Organizes Exocytotic Machinery

7 Polyunsaturated Fatty Acids Modulate Exocytosis via SNARE Proteins

8 Lipid Rafts, Ceramide, Sphingosine, and Cholesterol

9 Conclusions

Chapter three: A Planar Lipid Bilayer in an Electric Field

1 Introduction

2 A Quasi-Planar Membrane in a DC Electric Field

3 Impedance of a Planar Membrane in an AC Electric Field

4 Conclusion

Appendix Robin-type BC

Chapter four: Raft Formation in Cell Membranes

1 Introduction

2 Lipid Membranes with Cholesterol Recycling

3 Protein-Induced Nanodomain Stabilization in Lipid Membranes

4 Tuning Membrane Lipid Heterogeneity Near the Phase Boundary

5 Conclusions

Chapter five: Statistical Thermodynamics of Adhesion Points in Supported Membranes

1 Introduction

2 Lattice-Gas Model for Adhesion Bonds in Supported Membranes

3 Statistical Mechanics of a Membrane with One Adhesion Point

4 Fluctuation-Induced Attraction Between Two Adhesion Points

5 The Strength of the Fluctuation-Induced Attraction

6 The Many-Body Problem

7 Conclusions

Chapter six: Monte Carlo Simulations of Lipid Bilayers and Liposomes Using Coarse-Grained Models

1 Introduction

2 Self-assembled Vesicles

3 Particular Physical Effects Resulting from Fluidity, Elasticity, and Concentration Fluctuations of Mixed Membranes

4 Models for Simulating More Complex Problems

5 Summary and Outlook

Chapter seven: Coarse-Grained Computer Simulations of Multicomponent Lipid Membranes

1 Introduction

2 Time-Dependent Ginzburg–Landau Simulations

3 Dynamic Triangulation Monte Carlo

4 Coarse-Grained Molecular Dynamics

5 Dissipative Particle Dynamics

6 Conclusion

Chapter eight: Fluorescence Spectroscopy Study of Hyaluronan–Phospholipid Interactions

1 Introduction

2 Fluorescence Probe Techniques

3 Materials and Methods

4 Phospholipid Aggregation

5 Presence of Hyaluronan

6 Mixed System

7 Conclusion

Chapter nine: Dynamics of Lipid Vesicles

1 Introduction

2 Dynamics of Thermally Induced Membrane Fluctuations of Quasispherical Lipid Vesicles

3 Dynamics of Vesicles in Unconfined Shear Flows: Overview of Theory and Experiments

4 Microscopic Signature on the Rheology of Vesicle and Red Blood Cell Suspensions

5 Concluding Remarks

Chapter ten: ß-Carotene–Lipid Interactions in Liposomes with Different Lipid Composition

1 Introduction

2 Materials and Methods

3 Results

4 Discussion

Subject Index

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