Nutritional And Therapeutic Interventions For Diabetes and Metabolic Syndrome

Nutritional And Therapeutic Interventions For Diabetes and Metabolic Syndrome, 1st Edition

Nutritional And Therapeutic Interventions For Diabetes and Metabolic Syndrome, 1st Edition,Debasis Bagchi,Sreejayan Nair,ISBN9780123850836

Bagchi   &   Nair   

Academic Press




235 X 191

Understand the intricate issues and mechanisms of the relationship between diabetes and metabolic syndrome, their prevention and treatment using proper nutrition and drug interventions.

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Key Features

  • Scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome
  • Includes coverage of Pre-diabetes conditions plus both Type I and Type II Diabetes
  • Presents both prevention and treatment options


Diabetes mellitus affects approximately 20 million people in the US, or nearly 7% of the population. It is expected to increase by 70% within the next 25 years, and numerous epidemiologic studies have demonstrated that type 2 diabetes increases the risk of cardiovascular morbidity and mortality. It is estimated to cost over $92 billion in health care costs and lost productivity. The increased risk is due to the detrimental vascular effects of prolonged exposure to a hyperglycemic, oxidant-rich environment yielding associated cardiovascular risk factors: atherosclerosis, hypertension and clotting abnormalities. Hypertension and dyslipidemia in diabetic patients produces substantial decreases in cardiovascular and microvascular diseases.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome provides an overview of the current epidemic, outlines the consequences of this crisis and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. The contributing experts from around the world give this book relevant and up-to-date global approaches to the critical consequences of metabolic syndrome and make it an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes.


Nutritionist researchers and practitioners, food microbiologists and toxicologists, and pharmacologists, public health officials, health professionals, endocrinologists, nurses and general practitioners

Debasis Bagchi

Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. He is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, TX, and Chief Scientific Officer at Cepham Research Center, Piscataway, NJ, Adjunct Faculty in Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Inc, Benicia, CA, from 1998 till Feb 2011, and then as Director of Innovation and Clinical Affairs, of Iovate Health Sciences, Oakville, ON, till June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the Past Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards (JIHFS), Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. Dr. Bagchi has 315 papers in peer reviewed journals, 27 books and 18 patents. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. Dr. Bagchi is the Associate Editors of the Journal of Functional Foods, Journal of the American College of Nutrition, and Archives of Medical and Biomedical Research, and also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, The Original Internist, and other peer reviewed journals.

Affiliations and Expertise

Department of Pharmacological and Pharmaceutical Sciences, University of Houston College of Pharmacy, TX, USA

View additional works by Debasis Bagchi

Sreejayan Nair

Dr. Sreejayan Nair is a Professor of Pharmacology and the Associate Dean for Research in the School of Pharmacy, College of Health Sciences, University of Wyoming. He also serves as the Director of the interdisciplinary Biomedical Sciences Graduate Program in the University of Wyoming. Dr. Nair earned his bachelors, masters and PhD degree in Pharmaceutical Sciences from the College of Pharmaceutical Sciences, Manipal, India. He received his post-doctoral trainings at the Department of Medicine-II, Ludwig Maximillians University, Klinikum Grosshadern, Munich, Germany, and at the Department of Physiology, University of Tennessee Health Sciences Center, Memphis, TN. His research interests are diabetes and cardiovascular disease. He has published over 75 research papers in peer-reviewed journals and presented at various national and international conferences. His research has been funded by the American Heart Association, American Diabetes Association, and the National Institutes of Health. He has co-edited three books related to diabetes and cardiovascular disease. He is a Fellow of the American College of Nutrition.

Affiliations and Expertise

School of Pharmacy, University of Wyoming, Laramie, WY, USA

Nutritional And Therapeutic Interventions For Diabetes and Metabolic Syndrome, 1st Edition

Chapter 1: Type1 Diabetes Mellitus: An Overview / Saleh Adi, Andrea Gerard Gonzalez
Chapter 2: An Overview on Type 2 Diabetes / Jonathan Pinkney, Julie Tomlinson, Elizabeth Stenhouse
Chapter 3: Pathogenesis of Type 2 Diabetes- A Comprehensive Analysis / Jeff Unger
Chapter 4: Managing the Broad Spectrum of Type 2 Diabetes / Evelyne Fleury-Milfort
Chapter 5: Prediabetes: Prevalence, Pathophysiology and Recognition of Enhanced Risk / Alok K. Gupta, Ajay Menon, William D. Johnson
Chapter 6: Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome / Santoro Nicola, Cosimo Giannini, Sonia Caprio
Chapter 7: Diabetes Pathophysiology- A Nutritional Perspective / Kevin J. Acheson
Chapter 8: Diabetes pathophysiology- A Nurse’s Perspective / Anne Jessup
Chapter 9: Roles of Environmental Pollution and Pesticides in the Metabolic Syndrome and Diabetes:  The Epidemiological Evidence / Ivar L. Frithsen, Charles J. Everett
Chapter 10: Preventing Diabetes with Diet and Exercise / Karen Z. Walker, Kerin O'Dea

Chapter 11: The Role of Insulin Resistance in the Cardiorenal Syndrome / Jaya P. Buddineni, Adam Whaley-Connell, James Sowers
Chapter 12: An Overview on Diabetic Nephropathy / Kei Fukami, Sho-ichi Yamagishi
Chapter 13: An Overview on Diabetes and Ocular Health / Shintaro Nakao, Yasuaki Hata
Chapter 14: An Overview on Diabetic Retinopathy / Stephen G. Schwartz, Harry W. Flynn, Jr.
Chapter 15: Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus / Francesco Tecilazich, Thanh L. Dinh, Aristidis Veves
Chapter 16: An Overview on Gestational Diabetes / Christopher Federico, Gabriella Pridjian

Chapter 17: Gene-Environment Interaction in the Pathogenesis of Type 2 Diabetes / Kian-Peng Goh
Chapter 18: Epigenetics in the Pathophysiology of Type 2 Diabetes / Charlotte Ling
Chapter 19: Targeting the metabolic syndrome and Type 2 Diabetes by preventing inflammation / Amin Ardestani, Luan Shu, Kathrin Maedler
Chapter 20: Interleukin-18 in Metabolic Syndrome and Diabetes / Marius Trøseid, Harald Arnesen, Ingebjørg Seljeflot

Chapter 21: Sleep, Hypertension and Diabetes / Michelle A. Miller, Frances P. Cappuccio
Chapter 22: Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle and Adipose Tissues in Diabetes and Metabolic Syndrome / Beverly S. Mühlhäusler
Chapter 23: Liver Disease: A Neglected Complication of Diabetes Mellitus / Marco Arrese, Juan Pablo Arab, Juan Pablo Arancibia, Roberto Candia, Arnoldo Riquelme, Francisco Barrera

Chapter 24: Antioxidants, Healthy Diet and Diabetes / Dario Pitocco, Francesca Martini, Francesco Zaccardi, Giovanni Ghirlanda
Chapter 25: Molecular Mechanisms of Diabetes Prevention by Structurally Diverse Antioxidants / Lucyna A. Wozniak, Katarzyna Cypryk, Marzena Wojcik
Chapter 26: Cardioprotective Roles of Selenium in Diabetes / Belma Turan, Guy Vassort
Chapter 27: Exercise and Physical Activity in the Prevention of Diabetes and Metabolic Syndrome / Cheri L. Gostic, Dawn Blatt
Chapter 28: An Overview on Nutraceuticals and Herbal Supplements for Diabetes and Metabolic Syndrome / Wadie I. Najm
Chapter 29: Therapeutic Effect of Fucoxanthin on Metabolic Syndrome and Type 2 Diabetes / Kazuo Miyashita, Show Nishikawa, Masashi Hosokawa
Chapter 30: Beneficial Effects of Chromium (III) and Vanadium Supplements in Diabetes / John B. Vincent
Chapter 31: Role of n-6 and n-3 Polyunsaturated Fatty Acids in Type 2 Diabetes / Jose Galgani, Pamela Rojas
Chapter 32: Effects of Supplemental Fiber in Type 2 Diabetes Mellitus / Candis M. Morello, Sarah A. Bajorek
Chapter 33: The Effects of Resveratrol on Diabetes and Obesity / Juan Sanchez, Mahesh Thirunavukkarasu, Nilanjana Maulik
Chapter 34: Meal Plans for Diabetics: Caloric Intake, Calorie Counting and Glycemic Index / Paulin Moszczynski, Jan Rutowski
Chapter 35: Ayurveda and Metabolic Diseases - Whole is greater than Sum of Parts / Amrutesh Puranik, Bhushan Patwardhan

Chapter 36: The Evolution of Glucose-Lowering Drugs for Type 2 Diabetes / Andrew J. Krentz, Alan J. Sinclair
Chapter 37: Anti-Diabetic Drugs For Elderly Population / Raffaela Marfella, Giuseppe Paolisso

Chapter 38: Diabetes Mellitus in Animals: Diagnosis and Treatment of Diabetes Mellitus in Dogs and Cats / Deborah S. Greco
Chapter 39: Overview of Diabetes Treatment in Animals / Erica L. Reineke


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