Regenerative Biology and Medicine

Regenerative Biology and Medicine, 2nd Edition

Regenerative Biology and Medicine, 2nd Edition,David Stocum,ISBN9780123848604


Academic Press




276 X 216

Fully updated source for the latest information on biology of regeneration and regenerative medicine, current applications and prospects for the future

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Key Features

  • Includes coverage od skin, hair, teeth, cornea, and central neural tissues
  • Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems
  • Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals


Since the publication of the first edition of Regenerative Biology and Medicine in 2006, steady advances have been made in understanding the origin and characteristics of stem cells in epithelia, skeletal muscle, and bone, and in the niche signals that regulate the activities of these cells. Simultaneously, breakthroughs including the creation of iPSCs and transdifferentiation have created a momentum for regenerative biology with implications in regenerative biology that are far-reaching.

This book highlights these advances in the field to embrace a vast audience of investigators in chemistry, computer science, informatics, physics and mathematics as well as graduate students, clinical physicians, and biologists who are realizing the importance of the fields of regenerative biology and medicine in practice. Organized in three parts - biology of regeneration, regenerative medicine, and perspectives - this second edition creates a framework for integrating old and new data in this progressive field.


Researchers and students in biology, chemistry, and bioengineering; medical students; academic and clinical physicians; and research investigators

David Stocum

Affiliations and Expertise

Department of Biology, Indiana University-Purdue University Indianapolis, USA

View additional works by David L. Stocum

Regenerative Biology and Medicine, 2nd Edition



1. An Overview of Regenerative Biology

2. Repair by Fibrosis

3. Regeneration of Epidermal Structures

4. Regeneration by of Neural Tissues

5. Regeneration of Digestive, Respiratory, and Urinary Tissues

6. Regeneration of Musculoskeletal Tissues


7. Regeneration of Cardiac Muscle and Hematopoietic Tissues


8. Regeneration of Appendages

9. Strategies of Regenerative Medicine

10. Development of Regenerative Therapies for Skin and Epidermal Structures

11. Regenerative Medicine of Neural Tissues

12. Development of Results of Regenerative Therapies for Digestive, Respiratory and Urinary Tissues

13. Development of Regenerative Therapies for Musculoskeletal Tissues

14. Development of Regenerative Therapies for Hematopoietic and Cardiovascular Tissues

15. Perspective

Quotes and reviews

"...a terrific reference for anyone toying with the idea of moving into this field. The text offers an enormous breath of coverage of different systems currently under investigation, and Stocum provides a central theme that pits regenerative ability against fibrosis as a way to conceptually untangle the limited regenerative capacity of humans...Stocum has erected an umbrella large enough for scientists of diverse backgrounds to initiate conceptual cross-talk between those actively involved in the biology of regeneration and those targeting its clinical application."
- Ken Muneoka, Department of Cell and Molecular Biology, Tulane University, New Orleans, Louisiana

“…of tremendous importance to researchers and clinicians working in the fields of regeneration and stem cell biology.”
- Jonathan Henry, University of Illinois at Urbana-Champaign

“This text integrates information from cell and developmental biology with regenerative biology, tissue engineering and clinical practice. The breadth and detail of this intellectual landscape are derived from the author’s long commitment to the problems of regeneration, and help to make this volume a landmark publication for regenerative medicine.”
- Jeremy Brockes, University College London

“This book is a superb in-depth analysis of the existing potential of the tissues of the body to replace cells and tissues and how to promote this ability for the sake of repair….Every institute should have it as their background reading and mission statement. I can't recommend it highly enough, it has been long awaited.”
- Malcolm Maden, King’s College London

“…wonderful and comprehensive, providing readers with the basis of regeneration biology and medicine. The author emphasizes the necessity of understanding the biology of regeneration for a true appreciation of its practice in clinical medicine.”
- Katsutoshi Yoshizato, University of Hiroshima
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