- Identification and characterization of Steroidogenic Factor-1 inverse agonists.
Mabrouka Doghman, Franck Madoux, Peter Hodder, and Enzo Lalli
- Assessment of inverse agonism for the angiotensin II type 1 receptor
Hiroshi Akazawa, Noritaka Yasuda, Shin-ichiro Miura, Issei Komuro
- Measurement of inverse agonism in BARs
Carlos Alberto Taira
- Inverse agonism of antidepressants: in vitro and in vivo studies
- Differential inverse agonism at the human muscarinic M3 receptor
- Ghrelin Receptor: High Constitutive Activity and Methods for Developing Inverse Agonists.
- Constitutive activity and inverse agonism at the a1a and a1b adrenergic receptor subtypes.
- Measurement of inverse agonism of the cannabinoid receptor
- Constitutively Active Thyrotropin (TSH) and Thyrotropin-Releasing Hormone (TRH) Receptors and Their Inverse Agonists
Marvin C. Gershengorn
- Inverse retinoid agonists and neutral antagonists
- y-Aminobutyric Acid Type A (GABAA) Receptor Subtype Inverse Agonists as Therapeutic Agents in Cognition
Gabriella Guerrini and Ciciani Giovanna
- Assays for inverse agonists in the visual system.
- Receptor-driven identification of novel human A3 adenosine receptor antagonists as potential therapeutic agents
Silvia Paoletta, Stephanie Federico, Giampiero Spalluto and Stefano Moro
- Inverse agonists of steroidogenic factor SF-1
Fabrice Piu and Andria L. Del Tredici
- Methods to Measure G Protein Coupled Receptor Activity for the Identification of Inverse Agonists
Gabriel Barreda-Gómez, M.Teresa Giralt and Rafael Rodríguez-Puertas
Section II-- Novel Strategies and Techniques for Constitutive Activity and Inverse Agonism
- Use of Pharmacoperones to Reveal GPCR Structural Components Associated with Receptor Activation and Trafficking
Jo Ann Janovick and P. Michael Conn
- Application of large-scale transiently transfected cells to functional assays of ion channels and other proteins.
Jun Chen, Sujatha Gopalakrishnan, Marc R Lake, and Bruce R Bianchi
- Quantification of RNA Editing of the Serotonin 2C Receptor (5-HT2CR) Ex Vivo
Maria Fe Lanfranco, Noelle C. Anastasio, Patricia K. Seitz, and Kathryn A. Cunningham
- Strategies for isolating constitutively-active and dominant-negative pheromone receptor mutants in yeast.
Mercedes Dosil and James B. Konopka
- Development of a GPR23 Cell-based ß-Lactamase Reporter Assay
Paul H. Lee and Bonnie J. Hanson
- Computational Modeling of Constitutively Active Mutants of GPCRs: C5a Receptor.
Gregory V. Nikiforovich and Thomas J. Baranski
- TSH receptor monoclonal antibodies with agonist, antagonist and inverse agonist activities
Jane Sanders, Ricardo Núñez Miguel, Jadwiga Furmaniak, Bernard Rees Smith
- Current standards, variations and pitfalls for the determination of constitutive TSHR activity in vitro
Sandra Mueller, Holger Jaeschke, Ralf Paschke
- Towards the Rational Design of Constitutively Active KCa3.1 Mutant Channels
Line Garneau, Hélène Klein, Lucie Parent, Rémy Sauvé
- Fusion proteins as model systems for the analysis of constitutive GPCR activity
Erich H. Schneider, Roland Seifert
- Screening for Novel Constitutively Active CXCR2 Mutants and Their Cellular Effects
Giljun Park, Tom Masi, Chang K. Choi, Heejung Kim, Jeffrey M. Becker, and Tim E. Sparer
- A method for parallel solid-phase synthesis of iodinated analogues of the cannabinoid receptor type I (CB1) inverse agonist rimonabant
Alan C. Spivey and Chih-Chung Tseng
- Coexpression systems as models for the analysis of constitutive GPCR activity
Roland Seifert and Erich H. Schneider
- Modelling and simulation of inverse agonism dynamics
Lloyd J. Bridge
- Design and Use of Constitutively Active STAT5 Constructs
Michael A. Farrar
- In vitro and in vivo assays of protein kinase CK2 activity
Renaud Prudent, Céline F. Sautel, Virginie Moucadel, Béatrice Laudet, Odilhe Filhol, and Claude Cochet