Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract

Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract, 1st Edition

Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract, 1st Edition,Klaus Kaestner,ISBN9780123812803

Progress in Molecular Biology and Translational Science

K Kaestner   

Academic Press




229 X 152

Reviews the latest developments in this field

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Key Features

* Discusses new discoveries, approaches, and ideas
* Contributions from leading scholars and industry experts
* Reference guide for researchers involved in molecular biology and related fields


Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine.

Klaus Kaestner

Affiliations and Expertise

Institute of Diabetes, Obesity & Metabolism, University of Pennsylvania School of Medicine, PA, USA

Development, Differentiation, and Disease of the Luminal Gastrointestinal Tract, 1st Edition

    1. Molecular regulation of vertebrate early endoderm development.
      Kim Tremblay
    2. Making boundaries: Separating intestine from stomach
      Deborah Gumucio
    3. Molecular Determinants of the Esophageal Epithelium
    4. Cdx genes, inflammation and the pathogenesis of Barrett's metaplasia.
      John Lynch
    5. Differentiation of the gastric mucosa
      Jason Mills
    6. Gastric Cancer Stem Cell
      Ramesh Shivdasani
    7. Oxyntic Atrophy and Gastric Cancer
      Jim Goldenring
    8. Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe?
      Juanita Merchant
    9. The Intestinal Stem Cell
      Calvin Kuo
    10. The role of the basement membrane as a modulator of intestinal epithelial-mesenchymal interactions
      Michele Kedinger
    11. Differentiation of Enteroendocrine Cells
      Andrew Leiter
    12. Controlling gene expression in the intestinal epithelium
      David Breault
    13. Inflammatory Bowel Disease, dysplacia and CRC
      Deborah Rubin
    14. Transcriptional Control of Exocrine Pancreas Development
      Ray MacDonald
    15. Molecular Basis of Pancreatic Cancer
      Ben Stanger
    16. Determinants of early liver development
      Klaus Kaestner
    17. Development of the Biliary Tree
      Frederic LeMaigre
    18. Transcriptional Control of Hepatic Differentiation
      Steve Duncan
    19. Fibrosis in the Liver: Acute protection and chronic disease
      Scott Friedman
    20. Adult Hepatic Progenitor Cells
      Bryon Petersen
    21. Molecular Determinants of Liver Zonation
      Sabine Colnot
    22. Signaling Pathways in Liver Development and Maintenance
      Satdarshan (Paul) Monga
    23. Cascades of transcription regulation during liver regeneration
      Michelle BARTON
    24. The Molecular Basis of Hepatocellular Carcinoma
      Peter Schirmacher


    Quotes and reviews

    "Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal

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