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The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents
 
 

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents, 1st Edition

 
The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents, 1st Edition,Mark Suckow,Karla Stevens ,Ronald Wilson,ISBN9780123809209
 
 
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Suckow   &   Stevens   &   Wilson   

Academic Press

9780123809209

9780123809216

1288

276 X 216

This single volume reference, arranged in section by species often used in research, includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model.

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Key Features

  • 2012 PROSE Award winner for Best Single Volume Reference in Science from the Association of American Publishers
  • One-stop resource for advancements in the humane and responsible care of: rabbit, guinea pig, hamster, gerbil, chinchilla, deer mouse, kangaroo rat, cotton rat, sand rat, and degu
  • Includes up-to-date, common experimental methods
  • Organized by species for easy access during bench research

Description

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents is a single volume, comprehensive book sanctioned by the American College of Laboratory Animal Medicine (ACLAM), covering the rabbit, guinea pig, hamster, gerbil and other rodents often used in research. This well-illustrated reference won a 2012 PROSE Award for Best Single Volume Reference in Science from the Association of American Publishers. The book includes basic biology, anatomy, physiology, behavior, infectious and noninfectious diseases, husbandry and breeding, common experimental methods, and use of the species as a research model. With many expert contributors, this will be an extremely valuable publication for biomedical researchers, laboratory animal veterinarians and other professionals engaged in laboratory animal science.

Readership

The primary audience for this work is biomedical researchers, laboratory animal veternarians, and other professionals engaged in laboratory animal science.

Mark Suckow

Director, Research Animal Resource, University of Minnesota, St. Paul, MN, USA

Affiliations and Expertise

Executive Director, Research Animal Resource, University of Minnesota, St. Paul, MN, USA

View additional works by Mark A. Suckow

Karla Stevens

Affiliations and Expertise

Ethicon Endo-Surgery, Inc., Sommerville, NJ, U.S.A.

Ronald Wilson

Affiliations and Expertise

Pennsylvania State University College of Medicine, Hershey, PA, U.S.A.

The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents, 1st Edition

Preface

List of Contributors

List of Reviewers

PART I. General

Chapter 1. Ethical Considerations and Regulatory Issues

Introduction

Ethical Concepts

Ethical Challenges

Institutional Animal Welfare Oversight

Regulations and Non-regulatory Considerations

Conclusion

REFERENCES

Chapter 2. Anesthesia and Analgesia

Pre-anesthetic Preparation

Controlled Substances

Pharmacology

Anesthesia Circuits

Anesthesia Monitoring and Support

Surgical Anesthesia

Post-operative Monitoring and Pain Assessment

REFERENCES

Chapter 3. Clinical Biochemistry and Hematology

Introduction

Clinical Biochemistry

Rabbit

Guinea Pig

Hamster

Other Rodents

Hematology

Rabbit

Guinea Pig

Hamster

Other Rodents

REFERENCES

Chapter 4. Euthanasia and Necropsy

Introduction

Euthanasia

Necropsy

Pathology Considerations

Acknowledgments

REFERENCES

Chapter 5. Zoonoses and Occupational Health

Introduction

Viral Diseases

Rickettsial Diseases

Chlamydial Diseases

Bacterial Diseases

Fungal Diseases

Cestode Infections

Arthropod Infections

Allergies

Prevention of Allergy and Zoonotic Disease

REFERENCES

PART II. Rabbits

Chapter 6. The Domestic Rabbit,

Introduction and Background

Phylogeny and Taxonomy

Geographic Origins and Diversity

Domestication and Breed Development

Ecology and Conservation

REFERENCES

Chapter 7. Rabbit Genetics and Transgenic Models

Rabbit Genetics

Transgenic Rabbits

Conclusions

REFERENCES

Chapter 8. Anatomy, Physiology, and Behavior

Introduction

External Features

Osteology

Oral Cavity

Abdominal Viscera

Urogenital System

Thoracic Viscera

Brain and Spinal Cord

Metabolism

Behavior

Acknowledgments

REFERENCES

Chapter 9. Rabbit Colony Management and Related Health Concerns

Introduction

Laboratory Management

Breeding

Nutrition

Nutritionally Related Diseases

REFERENCES

Chapter 10. Basic Experimental Methods in the Rabbit

Introduction

Handling and Restraint

Sampling Techniques

Compound Administration

Specialized Research Techniques

REFERENCES

Chapter 11. Polyclonal Antibody Production

Introduction

The Immunogen

Immunogen Dose

Route of Immunization

Immunization Schedule

Adjuvants

Summary

REFERENCES

Chapter 12. Toxicity and Safety Testing

Introduction

Toxicity Testing

Safety Testing

Metabolism and Toxicokinetics

Acknowledgments

REFERENCES

Chapter 13. Bacterial Diseases

Introduction

Pasteurellosis

Enterotoxemia

Tyzzer’s Disease

Colibacillosis

Salmonellosis

Staphylococcosis

Treponematosis

Necrobacillosis

Listeriosis

Tuberculosis

Tularemia

Proliferative Enteropathy

Miscellaneous Bacterial Diseases

REFERENCES

Chapter 14. Viral Diseases

Introduction

DNA Virus Infections

RNA Virus infections

REFERENCES

Chapter 15. Parasitic Diseases

Introduction

Protozoa

Arthropods

Helminths

REFERENCES

Chapter 16. Rabbit Neoplasia

Introduction

Neoplasms of Oryctolagus cuniculus

Neoplasms of Sylvilagus

Neoplasms of Lepus

REFERENCES

Chapter 17. Mycoses and Non-Infectious Diseases

Introduction

Mycotic Diseases

Non-Infectious Diseases

REFERENCES

Chapter 18. The Rabbit as an Experimental Model

Introduction

Cardiovascular Diseases

Ophthalmic Diseases

Central Nervous System Diseases

Respiratory Diseases

Urogenital Diseases

Gastrointestinal Diseases

Musculoskeletal Diseases

Multisystemic Diseases

Acknowledgments

REFERENCES

PART III. Guinea Pigs

Chapter 19. Taxonomy and History

Introduction

Taxonomy and Geographical Distribution

Origin and Domestication

Genetics

REFERENCES

Chapter 20. Anatomy, Physiology, and Behavior

Introduction

External Anatomy

Musculoskeletal System

Digestive System

Cardiovascular System

Pulmonary System

Genitourinary System

Nervous System

Special Senses

Behavior

REFERENCES

Chapter 21. Management, Husbandry, and Colony Health

Introduction

Handling

Housing

Reproduction and Breeding

Nutrition

Colony Health

Record Keeping

REFERENCES

Chapter 22. Basic Experimental Methods

Introduction

Handling and Restraint

Sampling Techniques

Compound Administration

Specialized Research Techniques

REFERENCES

Chapter 23. Infectious Diseases

Introduction

Viral infections

Bacterial infections

Fungal infections

Protozoa infections

Parasitic infections

REFERENCES

Chapter 24. Non-Infectious Diseases

Introduction

Cardiovascular System

Respiratory System

Gastrointestinal System

Urinary System

Endocrine System

Reproductive System

Musculoskeletal System

Integumentary System

Special Senses

Hematolymphatic System

Multisystemic Conditions

REFERENCES

Chapter 25. Guinea Pigs as Experimental Models

Introduction

Models of Disease

REFERENCES

PART IV. Hamsters

Chapter 26. Taxonomy and History

Taxonomy

Geographical Distribution

Origin and Domestication

Genetics

Acknowledgments

REFERENCES

Chapter 27. Anatomy, Physiology, and Behavior

Introduction

External Features

Musculoskeletal System

Digestive System

Circulatory System

Pulmonary System

Genitourinary System

Nervous System

Special Senses

Behavior

REFERENCES

Chapter 28. Management, Husbandry, and Colony Health

Introduction

Housing

Environmental Conditions

Nutrition

Breeding

Colony Health

Record Keeping

REFERENCES

Chapter 29. Biomedical Research Techniques

Introduction

General Non-Surgical Procedures

Injections and Intubations

Biological Specimen Collections

Other Surgical Procedures

REFERENCES

Chapter 30. Bacterial and Fungal Diseases

Introduction

Bacterial Diseases

Fungal Diseases

REFERENCES

Chapter 31. Viral Diseases

Introduction

DNA Viruses

RNA Viruses

Miscellaneous Viruses

REFERENCES

Chapter 32. Parasitic Diseases

Introduction

Protozoa

Nematodes

Arthropods

REFERENCES

Chapter 33. Non-Infectious Diseases

Introduction

Diseases Associated with Aging

Nutritional Disorders

Genetic, Traumatic, Environmental and Other Non-Infectious Diseases

Neoplasms

REFERENCES

Chapter 34. The Experimental Use of Syrian Hamsters

Introduction

Cancer Research

Metabolic Diseases

Non-Cancerous Respiratory Diseases

Cardiovascular

Infectious Disease Research

Other Models

REFERENCES

Chapter 35. The Chinese or Striped-Back Hamster

Introduction

Biology

Care and Husbandry

Cytogenetics and Fetal Development

Diseases

Research Uses

Summary

REFERENCES

Chapter 36. The European Hamster

Taxonomy

History

Biology

Behavior

Diseases

Management, Husbandry, and Colony Health

Experimental Methodology

Use in Biomedical Research

REFERENCES

Chapter 37. Other Hamsters

Introduction

Phodopus sungorus (Djungarian Hamster)

Mesocricetus brandti (Turkish Hamster)

Cricetulus migratorius (Armenian Hamster)

Mesocricetus newtoni (Romanian Hamster)

REFERENCES

PART V. Chinchillas

Chapter 38. Taxonomy and History

Introduction

Taxonomy

History

REFERENCES

Chapter 39. Anatomy, Physiology, and Behavior

Introduction

External Features

Unique Biological Characteristics

Behavior

REFERENCES

Chapter 40. Management, Husbandry, and Colony Health

Introduction

Housing Systems

Environmental Conditions

Nutrition

Breeding

Colony Health

Record Keeping

REFERENCES

Chapter 41. Basic Experimental Methods

Introduction

Handling and Restraint

Mechanical Methods

Sampling Techniques

Compound Administration

Specialized Research Techniques

REFERENCES

Chapter 42. Diseases and Veterinary Care

Introduction

Gastrointestinal and Metabolic Diseases

Traumatic Lesions

Management-Related Disorders

Neoplastic Diseases

Miscellaneous Conditions

REFERENCES

Chapter 43. Chinchillas as Experimental Models

Introduction

Models Related to Aural Disease

Models Related to Hearing Loss

Future of Chinchilla Models

REFERENCES

PART VI. Other Rodents

Chapter 44. Degu

Introduction

History and Taxonomy

Anatomy, Physiology, and Behavior

Management, Husbandry, and Colony Health

Handling and Restraint

Sampling Techniques

Compound Administration

Anesthesia and Analgesia

Euthanasia and Necropsy

Diseases

The Degu as an Experimental Model

REFERENCES

Chapter 45. Naked Mole Rat

History

Taxonomy

General Description

Natural Habitat

Behavior

Reproductive Behavior

General Physiology

Anatomy and Physiology of Organ Systems

Aging

Husbandry

Colony Health

Use in Research

REFERENCES

Chapter 46. Deer Mice, White-Footed Mice, and their Relatives

Introduction

Biology

Husbandry

Captive Breeding

Diseases

Anesthesia/Analgesia

REFERENCES

Chapter 47. Dormouse

Introduction

Taxonomy and History (Table 47.1)

Anatomic Characteristics

Husbandry

Nutrition

Housing

Environmental Conditions

Handling

Breeding

Diseases and Zoonoses

Colony Health Monitoring

Experimental Applications

Biomethodology

REFERENCES

Chapter 48. Kangaroo Rat

Introduction

Biology

Diseases

Use in Research

Laboratory Care

REFERENCES

Chapter 49. Cotton Rat

Introduction

Biology

Husbandry

Diseases

Experimental Methods

Use in Research

Acknowledgments

REFERENCES

Chapter 50. Pocket Gopher

Introduction

Biology

Diseases

REFERENCES

Chapter 51. White-Tailed Rat

Introduction

Taxonomy, History, and Genetics

Anatomy, Physiology, and Behavior

Management, Husbandry, and Colony Health

Basic Experimental Methods

Diseases and Veterinary Care

Experimental Models

REFERENCES

Chapter 52. Gerbils

Introduction

Taxonomy and History

Anatomy, Physiology, and Behavior

Management, Husbandry, and Colony Health

Basic Experimental Methods

Veterinary Care and Diseases

Gerbils as Experimental Models

REFERENCES

Chapter 53. Egyptian Fat-Tailed Jird

Introduction

Anatomy, Physiology, and Behavior

Management, Husbandry, and Colony Health

Diseases

Anesthesia/Analgesia, Euthanasia, and Necropsy

Use in Research

Basic Experimental Methods

REFERENCES

Chapter 54. Sand Rat

Introduction

Selection of Reliable Diets and Psammomys Lines for Diabetes Research

Metabolic Efficiency

Morphology, Physiology, Breeding Performance, and Husbandry

The Basis of Diabetes in Psammomys

The Relevance of Psammomys to Diabetes Research

The Genetic Basis of Psammomys Diabetes

Worldwide Research Using Psammomys

Complications of Diabetes in Psammomys

Concluding Remarks

REFERENCES

PART VII. Formulary and Normative Values

Chapter 55. Formulary

Introduction

Rabbit (Oryctolagus cuniculus)

Guinea Pig (Cavia porcellus)

Hamster (Mesocricetus auratus)

Degu (Octodon degus)

Other Species

REFERENCES

Chapter 56. Normative Values

Rabbits (Oryctolagus cuniculus)

Guinea pigs (Cavia porcellus)

Hamsters

Gerbils (Meriones unguiculatus)

Chinchillas (Chinchilla laniger)

Other rodents

REFERENCES

Index

Quotes and reviews

"...a thorough review of the responsible use of these species in research...a well organized, easily read volume that serves as both a handy reference and as an authoritative compilation."--Anticancer Research, February 2015

"The book is easy to use, despite its size, as the information is well indexed by diseases and species…I highly recommend this text as the editors with their 112 coauthors have met the goal to provide a comprehensive resource for laboratory rabbits, guinea pigs, hamsters, and other rodents."--Veterinary Pathology, September 2013


"…The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents serves as a thorough review of the responsible use of these species in research… a well organized, easily read volume that serves as both a handy reference and as an authoritative compilation."--Anticancer Research, Volume 33, issue no. 5, May 2013

 
 
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