Molecular Biology, 1st Edition

Molecular Biology, 1st Edition,David Clark,ISBN9780123785909
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Clark's "Molecular Biology" Academic Cell Update examines aspects that shapes Molecular Biology.  This Academic Cell Update Edition provides students with an integrated electronic study guide which includes current, relevant research from Cell Press along with tools to ease the integration of primary literature in undergraduate classrooms for both students and instructors.

Academic Cell is a collaboration between Cell Press and Academic Press, two market leading publishers dedicated to life science.  Cell Press is home to some of the most highly cited journals in the field of cell biology and Academic Press is known worldwide for publishing quality textbooks.  Academic Cell textbooks contain premium journal content from Cell Press and are part of this new cutting-edge textbook/journal collaboration designed to help today’s instructors teach students to "think like a scientist."

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Key Features

*Now with an online study guide with the most current, relevant research from Cell Press 

*Full supplements including test bank, powerpoint and online self quizzing

*Up to date description of genetic engineering, genomics, and related areas
* Basic concepts followed by more detailed, specific applications
* Hundreds of color illustrations enhance key topics and concepts
* Covers medical, agricultural, and social aspects of molecular biology
* Organized pedagogy includes running glossaries and keynotes (mini-summaries) to hasten comprehension


Molecular Biology: Academic Cell Update provides an introduction to the fundamental concepts of molecular biology and its applications. It deliberately covers a broad range of topics to show that molecular biology is applicable to human medicine and health, as well as veterinary medicine, evolution, agriculture, and other areas. The present Update includes the study guide with online content, journal specific images, and test bank. It also offers vocabulary flashcards and online self-quizzing called Test Prep. The book begins by defining some basic concepts in genetics such as biochemical pathways, phenotypes and genotypes, chromosomes, and alleles. It explains the characteristics of cells and organisms, DNA, RNA, and proteins. It also describes genetic processes such as transcription, recombination and repair, regulation, and mutations. The chapters on viruses and bacteria discuss their life cycle, diversity, reproduction, and gene transfer. Later chapters cover topics such as molecular evolution; the isolation, purification, detection, and hybridization of DNA; basic molecular cloning techniques; proteomics; and processes such as the polymerase chain reaction, DNA sequencing, and gene expression screening.


Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture

David Clark

BA (honors)Christ's College Cambridge, 1973 PhD University of Brsitol (England), 1977

Dr. Clark has taught courses in Molecular Biology and Bacterial Physiology and Biochemistry at Southern Illinois University since 1981. Research into the Regulation of Alcohol Fermentation in E. coli has been funded by the U.S. Department of Energy, Office of Basic Energy Sciences from 1982 till present. Supervised 11 master’s and 7 PhD students Published approximately 70 articles in scientific journals Previously published work includes "Molecular Biology Made Simple and Fun" coauthored with Lonnie Russell. (Cache River Press, Vienna, IL, First edition, 1997 and Second edition, 2000)

Affiliations and Expertise

Southern Illinois University, Carbondale, IL, USA

View additional works by David P. Clark

Molecular Biology, 1st Edition

Chapter 1 Basic Genetics

Chapter 2 Cells and Organisms

Chapter 3 DNA, RNA and Protein

Chapter 4 Genes, Genomes and DNA

Chapter 5 Cell Division and DNA Replication

Chapter 6 Transcription of Genes

Chapter 7 Protein Structure and Function

Chapter 8 Protein Synthesis

Chapter 9 Regulation of Transcription in Prokaryotes

Chapter 10 Regulation of Transcription in Eukaryotes

Chapter 11 Regulation at the RNA Level

Chapter 12 Processing of RNA

Chapter 13 Mutations

Chapter 14 Recombination and Repair

Chapter 15 Mobile DNA

Chapter 16 Plasmids

Chapter 17 Viruses

Chapter 18 Bacterial Genetics

Chapter 19 Diversity of Lower Eukaryotes

Chapter 20 Molecular Evolution

Chapter 21 Nucleic Acids: Isolation, Purification, Detection, and Hybridization

Chapter 22 Recombinant DNA Technology

Chapter 23 The Polymerase Chain Reaction

Chapter 24 Genomics and DNA Sequencing

Chapter 25 Analysis of Gene Expression

Chapter 26 Proteomics: The Global Analysis of Proteins



Quotes and reviews

"This is an excellent book. It is very lucidly written. Clark covers a suitable set of topics, and treats each topic very thoroughly...He is very up-to-date in his coverage of the material."
- John G. Burr, University of Texas at Dallas

"This textbook is very comprehensive, covering nearly all aspects of molecular biology and genetics. The textbook excels in defining key terms in a clear and understable way...The sprinkling of little side stories...keeps the reader interested, and kept me glued throughout the text."
- B. Franklin Pugh, Penn State University

"The author did a very good job covering this vast subject and offered many insightful perspectives."
- John F. Cannon, University of Missouri
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