Fundamentals of Osteoporosis, 1st Edition,Robert Marcus,David Feldman,Dorothy Nelson,Clifford Rosen,ISBN9780123750983
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Fundamentals of Osteoporosis, 1st Edition

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Editor(s) : Marcus  &   Feldman  &   Nelson  &   Rosen  

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Imprint: Academic Press

ISBN: 9780123750983

Pages: 552

Dimensions: 276 X 216

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Key Features

  • Presents a concise yet comprehensive source of all the latest basic research related to osteoporosis in one reference work
  • Experts from all areas of osteoporosis research expose readers to genomic and proteomic analysis, histopathology and imaging, as well cellular and molecular mechanisms relevant to assay development and drug discovery

  • Clear, concise presentations by bone biologists of the cellular and molecular mechanisms underlying osteoporosis

Readership

Academic, medical, and pharmaceutical researchers in bone biology, endocrinology, and rheumatology; Medical researchers in pediatrics, internal medicine, orthopedics, primary care, geriatrics, obstetrics and gynecology, oncology, and nephrology.

Robert Marcus

MD

Affiliations and Expertise

Emeritus, Department of Medicine, Stanford University School of Medicine, Stanford, California, U.S.A.

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David Feldman

David Feldman, MD, is Emeritus Professor of Medicine (Active) at Stanford University School of Medicine where he has been on the faculty since 1974. He has been a full professor since 1984 and was chief of the Endocrinology Division for 10 years. His laboratory studies the role of steroid hormone receptors, particularly the vitamin D receptor, and its mechanism of action. His current major research focus is hormone-dependent cancer including breast cancer and prostate cancer and the pathways by which vitamin D inhibits cancer growth. Professor Feldman is actively involved in both basic science approaches to the anti-cancer actions of vitamin D as well as to clinical trials studying the use of vitamin D in breast and prostate cancer. Professor Feldman was recently honored with an award for a Career of Outstanding Contributions to Vitamin D Research. He has authored over 290 medical research articles, reviews, editorials, and book chapters. In addition to being a co-editor of all four editions of OSTEOPOROSIS, he is the editor-in-chief of Vitamin D, just published in its third edition.

Affiliations and Expertise

Emeritus Professor of Medicine, Stanford University School of Medicine, Stanford, California, USA

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Dorothy Nelson

Affiliations and Expertise

Wayne State University, Detroit, MI, U.S.A.

Clifford Rosen

Dr. Rosen is Professor and Senior Scientists at The Jackson Laboratory, Bar Harbor, Maine, where his group studies the role of insulin-like growth factors on bone and the genetics of osteoporosis in inbred strains of mice. In 2007 he joined the Maine Medical Center Research Institute in Scarborough, Maine. He is also the former Director of the Maine Center for Osteoporosis Research and Education, St. Joseph Hospital, Bangor. Dr. Rosen is a Past President of the American Society of Bone and Mineral Research (ASBMR). He served five years as the First Editor in Chief of the Journal of Clinical Densitometry, the official journal for the International Society of Clinical Densitometry, and currently serves as Associate Editor of the Journal of Bone and Mineral Research. His publications exceed 270 manuscripts published in a wide spectrum of clinical and basic science journals.

Affiliations and Expertise

The Jackson Laboratory, Bar Harbor, Maine, U.S.A.

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Fundamentals of Osteoporosis, 1st Edition

1) The Bone Organ System: Form and Function
Elise F. Morgan, George L. Barnes, and Thomas A. Einhorn

2) The Nature of Osteoporosis
Robert Marcus and Mary L. Bouxsein

3) Skeletal Heterogeneity and the Purposes of Bone Remodeling
A.M. Parfitt

4) Osteoblast Biology
Jane B. Lian and Gary S. Stein

5) Osteoclast Biology
Harry C. Blair, Scott Simonet, David L. Lacey, and Mone Zaidi

6) Osteocytes
Lynda F. Bonewald

7) The Regulatory Role of Matrix Proteins in Mineralization of Bone
Wei Zhu, Pamela G. Robey, and Adele L. Boskey

8) Development of the Skeleton
Sylvain Provot, Ernestina Schipani, Joy Wu, and Henry Kronenberg

9) Mouse Genetics as a Tool to Study Bone Development and Physiology
Clifford J. Rosen and Wesley G. Beamer

10) Parathyroid Hormone and Parathyroid Hormone-Related Protein
Robert A. Nissenson

11) Vitamin D: Biology, Action, and Clinical Implications
David Feldman, Peter J. Malloy, Aruna V. Krishnan, and Eva Balint

12) Regulation of Bone Cell Function by Estrogens
Barry S. Komm, Boris Cheskis, and Peter V.N. Bodine

13) Androgens and Skeletal Biology: Basic Mechanisms
Kristine M. Wiren

14) Phosphatonins
Peter J. Tebben, Theresa J. Berndt, and Rajiv Kumar

15) Wnt Signaling in Bone
Mark L. Johnson and Robert R. Recker

16) Cytokines and Bone Remodeling
Gregory R. Mundy, Babatunde Oyajobi, Gloria Gutierez, Julie Sterling, Susan Padalecki, Florent Elefterious, and Ming Zhao

17) Skeletal Growth Factors
Ernesto Canalis

18) Intercellular Communication during Bone Remodeling
T. John Martin, Gideon A. Roda

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Fundamentals of Osteoporosis