Diffusion MRI

Diffusion MRI, 2nd Edition

From Quantitative Measurement to In vivo Neuroanatomy

Diffusion MRI, 2nd Edition,Heidi Johansen-Berg,Timothy E.J. Behrens,ISBN9780123964601

Johansen-Berg   &   Behrens   

Academic Press




276 X 216

The first comprehensive reference to cover all aspects of diffusion MRI technology and how to use the technology in neuroscience studies from acquisition through analysis to interpretation

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Key Features

  • Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging
  • Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments
  • New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain
  • Provides practical advice on running an experiment
  • Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience
  • Full color throughout


Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments.

Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo.

This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.


Neuroscientists interested in the study of connections in the brain, brain imaging, within Cognitive Neuroscience, Neuroscience, Radiology, Medical Physics and adjacent areas.

Heidi Johansen-Berg

Affiliations and Expertise

Oxford Centre for Functional MRI of the Brain (FMRIB), Department of Clinical Neurology, University of Oxford, UK

Timothy E.J. Behrens

Affiliations and Expertise

Department of Experimental Psychology, University of Oxford; Centre for Functional MRI of the Brain (FMRIB), UK

Diffusion MRI, 2nd Edition

Section I: Introduction to Diffusion MRI
1. Introduction to diffusion MR
2. Pulse Sequences for Diffusion-Weighted MRI
3. Diffusion Acquisition: Pushing the Boundaries
4. Geometric Distortions in Diffusion MRI
5. Gaussian Modeling of the Diffusion Signal
6. Multiple Fibers: Beyond the Diffusion Tensor

Section II: Diffusion MRI for Quantitative Measurement
7. White Matter Structure: A Microscopist's View
8. The Biological Basis of Diffusion Anisotropy
9. Inferring Microstructural Information of White Matter from Diffusion MRI
10. Cross-Subject Comparison of Local Diffusion MRI Parameters
11. Diffusion MRI in Neurological Disorders
12. Diffusion Tensor Imaging in the Study of Aging and Age-Associated Neural Disease
13. Diffusion Imaging in teh Developing Brain
14. Individual Differences in White Matter Microstructure in the Healthy Brain
15. Diffusion Tensor Imaging and its Applications to Schizophrenia and Related Disorders

Section III: Diffusion MRI for In Vivo Neuroanatomy
16. Mapping Connections in Humans and Non-Human Primates: Aspirations and Challenges for Diffusion Imaging
17. Classic and Contemporary Neural Tract-Tracing Techniques
18. The Human Connectome: Linking Structure and Function in the Human Brain
19. MR Diffusion Tractography
20. Validation of Tractography
21. Connectivity Fingerprinting of Gray Matter
22. Contribution of Diffusion Tractography to the Anatomy of Language
23. Presurgical Tractography Applications
24. Comparing Connections in the Brains of Humans and Other Primates Using Diffusion-Weighted Imaging
25. Imaging Structure and Function

Quotes and reviews

"This text outlines the theory and applications of diffusion magnetic resonance imaging (MRI). In 25 chapters, radiologists, neuroscientists, psychologists, psychiatrists, and others from North America, Europe, and Israel outline the methods underlying diffusion imaging; the use of diffusion MRI for quantitative measurement and in understanding neurological disorders…"--ProtoView.com, April 2014

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