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RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways
 
 

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways, 1st Edition

 
RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways, 1st Edition,Lynne E. Maquat,Megerditch Kiledjian,ISBN9780123745842
 
 
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Methods in Enzymology

Maquat   &   Kiledjian   

Academic Press

9780123745842

9780080923321

464

229 X 152

Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway

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Key Features

* Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway
* Expert researchers introduce the most advanced technologies and techniques
* Offers step-by-step lab instructions, including necessary equipment and reagents

Description

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.

Readership

Biochemists and researchers in related life science disciplines.

Lynne E. Maquat

Affiliations and Expertise

University of Rochester, NY, USA

View additional works by Lynne E. Maquat

Megerditch Kiledjian

Affiliations and Expertise

Rutgers University, New Brunswick, NJ, USA

RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways, 1st Edition

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