Origin and Evolution of Viruses

Origin and Evolution of Viruses, 2nd Edition

Origin and Evolution of Viruses, 2nd Edition,Esteban Domingo,Colin Parrish,John Holland,ISBN9780123741530

Domingo   &   Parrish   &   Holland   

Academic Press




189 X 246

Unique transdisciplinary coverage of basic concepts in virus evolution and their application to the understanding of evolution and pathogenesis of viruses such as hepatitis, influenza and herpes viruses.

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Key Features

* NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution
* UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups
* SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts


New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.


Animal and plant virologists working in research and teaching. Evolutionary biologists and ecologists. Experts in public health, disease surveillance and zoonotic viral disease.

Esteban Domingo

Esteban Domingo studied chemistry and biochemistry at the University of Barcelona, Spain and spent postdoctoral stays at the University of California, Irvine and the University of Zürich. His main interests are the quasispecies structure of RNA viruses and the development of new antiviral strategies. He is presently Professor of Research of the Spanish Research Council (CSIC) at Centro de Biología Molecular "Servero Ochoa" in Madrid.

Affiliations and Expertise

Centro de Biologia Molecular Severo Ochoa, Madrid, Spain

View additional works by Esteban Domingo

Colin Parrish

Affiliations and Expertise

Cornell University, Ithaca, NY, USA

John Holland

Affiliations and Expertise

University of California, San Diego, La Jolla, USA

Origin and Evolution of Viruses, 2nd Edition

1. Early Replication: Origin and Evolution
Peter Schuster and Peter F. Stadler

2. Structure and Evolution of Viroids
Núria Duran-Vila, Santiago F. Elena, José-Antonio Daròs and Richard Flores

3. Mutation, Competition and Selection as Measured with Small RNA Molecules
Christof K. Biebricher

4. Viral Quasispecies: Dynamics, Interactions and Pathogenesis
Esteban Domingo, Cristina Escarmís, Luis Menéndez-Arias, Celia Perales, Mónica Herrera, Isabel S. Novella and John J. Holland

5. Comparative Studies of RNA Virus Evolution
Edward C. Holmes

6. Nucleic Acid Polymerase Fidelity and Viral Population Fitness
Eric Smidansky, Jamie J. Arnold and Craig E. Cameron

7. The complex Interactions of Viruses and the RNAi Machinery: A Driving Force in Viral Evolution
Ronald P. van Rij and Raul Andino

8. The Role of the APOBEC3 Family of Cytidine Deaminases in Innate Immunity, G-to-A Hypermutation, and Evolution of Retroviruses
Marie L. Santiago and Warner C. Greene

9. Lethal Mutagenesis
J.J. Bull and C.O. Wilke

10. Evolution of dsDNA Tailed Phages
Roger W. Hendrix

11. More about Plant Virus Evolution – Past, Present and Future
Adrian Gibbs, Mark Gibbs, Kazusato Ohshima and Fernando García-Arenal

12. Mutant clouds and bottleneck events in plant virus evolution
Marilyn J. Roossinck

13. Retrovirus Evolution
Simon Wain-Hobson

14. Intra-host dynamics and evolution of HIV Infection
Viktor Müller and Sebastian Bonhoeffer

15. The Impact of Rapid Evolution of Hepatitis Viruses
J. Quer, M. Martell, F. Rodriguez, A. Bosch, R. Jardi, M. Buti and J.I. Esteban

16. Arbovirus Evolution
Kathryn A. Hanley and Scott C. Weaver

17. Evolution and Variation of the Parvoviruses
Karin Hoelzer and Colin R. Parrish

18. Genome Diversity and Evolution of Papillomaviruses
Hans-Ulrich Bernard

19. Origin and Evolution of Poxviruses
John W. Barrett and Grant McFadden

20. Molecular Evolution of the Herpesvirales
Duncan J.McGeoch, Andrew J. Davison, Aidan Dolan, Derek Gatherer and Edgar E. Sevilla-Reyes

21. The widespread evolutional significance of viruses
Luis P. Vollareal

Quotes and reviews

Review of the previous edition:
"...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects"--TODAY'S LIFE SCIENCE (February 2001)
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