Long-Range Control of Gene Expression

Long-Range Control of Gene Expression, 1st Edition

Long-Range Control of Gene Expression, 1st Edition,Veronica van Heyningen,Robert Hill,ISBN9780123738813

Advances in Genetics

van Heyningen   &   Hill   

Academic Press




229 X 152

The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

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Key Features

* Discusses the evolution of cis-regulatory sequences in drosophila
* Includes information on genomic imprinting and imprinting defects in humans
*Includes a chapter on epigenetic gene regulation in cancer


This volume covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced.


Molecular geneticists, clinical geneticists, neurologists, neuroscientists, molecular biologists and biochemists, cell and developmental biologists

Veronica van Heyningen

Affiliations and Expertise

Veronica van Heyningen [v.vanheyningen@hgu.mrc.ac.uk]

Information about this author is currently not available.

Long-Range Control of Gene Expression, 1st Edition

Chromatin Structure and the Regulation of Gene Expression: The Lessons of Pev in Drosophila

Polycomb Group Proteins and Long-Range Gene Regulation

Evolution of cis-Regulatory Sequences in Drosophila

Beta Globin Regulation and Long-Range Interactions

Long-Range Regulation of Ą-globin Gene Expression

Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution

Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators

Genomic Imprinting and Imprinting Defects in Humans

Epigenetic Gene Regulation in Cancer

Genomic Identification of Regulatory Elements by Evolutionary Sequence Comparison and Functional Analysis

Regulatory Variation and Evolution and Implications for Disease

Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes

Long-Range Gene Control and Genetic Disease
Dirk A. Kleinjan and Laura A. Lettice

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