Textbook of Nephro-Endocrinology

Textbook of Nephro-Endocrinology, 1st Edition

Textbook of Nephro-Endocrinology, 1st Edition,Ajay Singh,Gordon Williams,ISBN9780123738707

Singh   &   Williams   

Academic Press

9780123738707 New edition



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Key Features

  • Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems
  • Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work
  • Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field


The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.


Researchers and clinicians in nephrology and endocrinology

Ajay Singh


Affiliations and Expertise

Clinical Chief, Renal Division, Brigham and Women's Hospital; Associate Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

Gordon Williams

Affiliations and Expertise

Director, Center for Clinical Investigation, Brigham and Women's Hospital, Professor of Medicine, Harvard Medical School, Cambridge, MA, USA

View additional works by Gordon H. Williams

Textbook of Nephro-Endocrinology, 1st Edition

Part 1: The Kidney as an Endocrine Organ

Section 1: Erythropoietin
1.Erythropoientin: An Historical Overview of Physiology, Molecular Biology
And Gene Regulation
David R. Mole, Peter J. Ratcliffe

2.Erythropoiesis: The Role of Erythropoietin and Iron
Herbert Lin

3.Extra-Hematopoietic Action of Erythropoietin
Zheqing Cai, Gregg Semenza

4.Development of Recombinant Erythropoietin and Erythropoietin Analogues
Iain Macdougall

5.Erythropoietin Disease States & Resistance
Ajay K. Singh, Tejas Patel, Shona Pendse, Sairam Keithi-Reddy
Section 2: Vitamin D, PTH and Novel Regulators of Phosphate

6.Vitamin D and the Kidney: Introduction and Historical Perspective
Ajay K. Singh, Tejas Patel

7. Vitamin D: Molecular Biology and Gene Regulation
Adriana Dusso, Alex J. Brown

8. Molecular Biology of Parathyroid Hormone
Peter A. Friedman

9.Endocrine Regulation of Phosphate Homeostasis
Harald Jüppner
Section 3: Renin-angiotensin
10.Introduction and Historical Overview
Joel Menard

11.Molecular Biology of Renin and Regulation of Its Gene
Timothy L. Reudelhuber, Daniel F. Catanzaro

12. Physiology and Regulation of the RAAS System
Robert Carey, Shetal H. Padia

13. The Renin Angiotensin Aldosterone System and the Kidney
George Bakris, Benjamin Ko

14. The Renin Angiotensin and the Heart
Carlos Ferrario, Aaron Trask

15. The Renin-Angrotensin blockade: Therapeutic Agents
Domenic Sica
Part 2: The Kidney as a Hormonal target
Section 4: Anti-diuretic Hormone
16. Vasopressin in the Kidney: Historical Aspects
Jeffrey Sands, Lynn E. Schlanger

17. Molecular Biology and Gene Regulation
Carolyn Ecelbarger, Swasti Tiwari

18. Vasopressin Antagonists in Physiology and Disease
Tomas Berl, Robert W. Schrier

19. Diabetes Insipidus and SIADH
J Carlos Ayus, Michael Moritz

Section 5: The Atrial Natriuretic Peptides

20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis
John C Burnett, Jr., Candace Lee

Section 6: Aldosterone
21.Introduction and Historical Overview
John Coghlan, James Tait

22.Aldosterone Receptors and Their Renal Effects: Molecular Biology
And Gene Regulation
Celso Gomez-Sanchez, Elise P. Gomez-Sanchez, Mario Galigniana
23. Aldosterone and Its Cardiovascular Effects
Gail K Adler, Rajesh Garg

24. Aldosterone Regulation
William Rainey, Wendy B. Bollag, Carlos M. Isales
Section 7: Endocrine Disorders in Renal Failure

25. Insulin resistance
Donald Simonson

26. Growth hormone
John Mahan

27.Sexual Dysfunction in Men and Women with Chronic Kidney Disease
Biff F. Palmer

28.Thyroid Status in Chronic Renal Failure Patients
Victoria Lim, Manish Suneja

29.Metabolic Acidosis of Chronic Kidney Disease
Jeffrey A. Kraut, Glenn T. Nagami

30.Pregnancy and the Kidney
Ananth Karumanchi, Chun Lam

Quotes and reviews

"This well-written, relatively concise, and current book will find a home on the shelves of many nephrologists and endocrinologists. Because it is so readable, it should be useful for students, experts, and those in between. I know I will consult my copy on a frequent basis - an unusual event in this era of online material." --N Engl J Med, 2009

"All in all, this is a solid book that provides substantial up-todate information on endocrine aspects of the kidney. I will be glad to pull it down from my shelf rather than one of the true heavyweights to which I would previously have gone for this kind of reading." --Kidney International, 2009

"Written by multidisciplinary experts from several countries, this book is divided into 2 parts and 7 sections. A very useful volume. Each chapter is richly referenced." --Pediatric Endocrinology Reviews

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