Viruses and Human Disease

Viruses and Human Disease, 2nd Edition

Viruses and Human Disease, 2nd Edition,Ellen Strauss,James Strauss,ISBN9780123737410


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Key Features

* Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information
* Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia.
* Further reading sections at the end of each chapter make it easy find key references
* World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
* A companion website features illustrations for use in class notes and presentations.


Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease.


Students and professionals in virology, molecular biology, and microbiology

Ellen Strauss

Affiliations and Expertise

California Institute of Technology, U.S.A.

James Strauss

Affiliations and Expertise

California Institute of Technology, U.S.A.

Viruses and Human Disease, 2nd Edition

Preface to the Second Edition Chapter 1. Overview of Viruses and Virus Infection Introduction Classification of Viruses An Overview of the Replication Cycle of Viruses Effects of Virus Infection on the Host Cell Epidemiology: The Spread of Viruses from Person to Person Further Reading Chapter 2. The Structure of Viruses Introduction Helical Symmetry Icosahedral Symmetry Nonenveloped Viruses with More Complicated Structural Features Enveloped Viruses Assembly of Virions Stability of Virions Further Reading Chapter 3. Plus-Strand RNA Viruses Introduction Family Picornaviridae Family Caliciviridae Family Hepeviridae Family Astroviridae Family Togaviridae Family Flaviviridae Family Coronaviridae Family Arteriviridae Family Roniviridae The Plus-Strand RNA Viruses of Plants Origin and Evolution of Plus-Strand RNA Viruses Further Reading Chapter 4. Minus-Strand RNA Viruses Introduction Overview of the Minus-Strand RNA Viruses Family Rhabdoviridae Family Paramyxoviridae Family Filoviridae Family Bornaviridae Family Orthomyxoviridae Family Bunyaviridae Family Arenaviridae Evolution of Minus-Strand RNA Viruses Further Reading Chapter 5. Viruses That Contain Double-Stranded RNA: Family Reoviridae Introduction Overview of the Family Reoviridae Further Reading Chapter 6. Viruses Whose Life Cycle Uses Reverse Transcriptase Introduction Family Retroviridae Family Hepadnaviridae Further Reading Chapter 7. DNA-Containing Viruses Introduction Family Poxviridae Family Herpesviridae Replication of Herpesviruses Family Adenoviridae Family Polyomaviridae Family Papillomaviridae Family Parvoviridae Torque Teno Virus: A Newly Described Human Virus Further Reading Chapter 8. Emerging and Reemerging Viral Diseases Bat-Associated Viruses Viruses Associated with Birds Viruses Associated with Primates Viruses Associated with Rodents Further Reading Chapter 9. Subviral Agents Introduction Defective Interfering Viruses Satellites and Satellite Viruses Viroids and Virusoids Hepatitis d Prions and Prion Diseases Prions of Yeast Further Reading Chapter 10. Host Defenses against Viral Infection and Viral Counterdefenses Introduction Adaptive Immune System Innate Immune System Viral Counterdefenses Interactions of Viruses with Their Hosts Further Reading Chapter 11. Gene Therapy Introduction Virus Vector Systems Use of Viruses as Expression Vectors Gene Therapy Further Reading Appendix: References Used for Figures and Tables Index

Quotes and reviews

"...exceptionally easy to read and full of 'need-to know' material appropriate for students. ...well organized and thoughtfully prepared."
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